Clinical trials: Anxiety Depression Disorder
Depression, Anxiety
Behavioral Telehealth in Low-resource Primary Care Settings for Anxiety and Depression in Youth
The goal of this clinical trial is to test a brief, behavioral telehealth treatment program (STEP-UP) for depression and anxiety in youths (age 8-16 years old).
- Trial name
- STEP-UP (NCT06273982)
- Testing
- STEP-UP (transdiagnostic behavioral therapy for pediatric anxiety and depression), ARC (assisted referral to community care)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- San Diego State University
Quality of Life, Insomnia
The Efficacy of Group-based Unified Protocol (UP) Programme for Improving Sleep and Mental Health
Common mental disorders can be disabling and lead to a large burden of disease. Unified Protocol for Transdiagnostic Treatment of Emotional Disorders was developed to address emotional disorders with evidence-based…
- Conditions
- Quality of Life, Insomnia, Depression, Anxiety
- Trial name
- NCT05394753
- Testing
- Unified Protocol for mood disorders
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Depression, Anxiety
ACTing Minds: An ACT-based Videogame for Mental Health
The goal of this clinical trial is to test whether a single-session Acceptance and Commitment Therapy (ACT) videogame (ACTing Minds) improves psychological flexibility and mental health in adults who report mild to moderate…
- Conditions
- Depression, Anxiety, Stress (Psychology), Psychological Flexibility
- Trial name
- ACTingMindsRCT (NCT07272096)
- Testing
- ACTing Minds (ACT videogame), Monument Valley (mobile; neutral control)
- Where
- United Kingdom
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Swansea University
Postpartum Depression, Postpartum Anxiety
Improving Maternal Sleep and Mental Health
The goal of this clinical trial is to test the effectiveness of a Smart Bassinet to prevent/mitigate postpartum mood disorders by augmenting maternal sleep and/or enhancing infant sleep.
- Conditions
- Postpartum Depression, Postpartum Anxiety, Sleep Disturbance, Infant Behavior
- Trial name
- SHINE (NCT06544941)
- Testing
- Smart Bassinet, HALO
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Anxiety Disorders, Depressive Disorder
Effectiveness and Underlying Mechanisms of Applied Relaxation as Indicated Preventive Intervention
As mental disorders constitute a core health care challenge of the 21th century, increased research efforts on preventive interventions are indispensable.
- Conditions
- Anxiety Disorders, Depressive Disorder, Stress Disorder
- Trial name
- EASY (NCT03311529)
- Testing
- Applied Relaxation
- Where
- Germany
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Older Adults, Healthy Aging
danceSing Care Evaluation: Testing the Effectiveness
This pilot randomised controlled trial aims to compare the effectiveness of a 12-week music and movement intervention in older adults in care homes compared to a waitlist control group.
- Conditions
- Older Adults, Healthy Aging, Aging, Quality of Life
- Trial name
- NCT05601102
- Testing
- danceSing Care
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Anxiety, Depression
A Feasibility Study of a Guided Self-help Programme for Male Offenders Serving a Long-term Prison Sentence
Background: Prisoners have complex mental health needs, and there is a disproportionately higher incidence of mental health problems compared with the general population.
- Trial name
- NCT04746651
- Testing
- Guided Self Help
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Chronic Low-back Pain, Anxiety
EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain
The aim of this randomized controlled trial (RCT) is to assess outcomes for virtual reality therapy (including pain intensity, pain interference, anxiety, depression, physical function, sleep, behavioral skills development…
- Conditions
- Chronic Low-back Pain, Anxiety, Depression
- Trial name
- AVR_HEOR (NCT05263037)
- Testing
- EaseVRx
- Where
- United States
- Volunteers
- 1,093 people
- Sponsor
- AppliedVR Inc.
Posttraumatic Stress Disorder, Depression
Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events
Background: International studies have shown that a substantial number of children and adolescents are exposed to potentially traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT02299583
- Testing
- Preventive intervention trauma-informed early intervention
- Where
- Denmark
- Volunteers
- 684 people
- Sponsor
- Carolina Magdalene Maier
Well-being, Depression
Differential Effect of Four Mindfulness Exercises
Mindfulness can be considered as a family of complex attentional and emotional regulation strategies that promote the cultivation of well-being and emotional balance.
- Conditions
- Well-being, Depression, Anxiety
- Trial name
- NCT02191553
- Testing
- Control group relaxation techniques, Loving-kindness meditation, Body scan
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Anxiety, Depressive Symptoms
Online or In-person Interventions on Anxiety and Depression Symptoms in Caregivers of Patients with Cancer
Oncological diseases are considered a family disease because when one member is diagnosed with cancer, the psycho-physical, social and economic consequences affect the entire family.
- Trial name
- CBT_ONLINE (NCT06592573)
- Testing
- CBT_ONLINE, CBT_IN PERSON
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Depression, Anxiety
Cardiovascular Biomarkers and Quetiapine in Depression and Anxiety Patients
No suitable treatment has been identified to reverse and ideally prevent, the cardiovascular disease risk associated with depression and anxiety.
- Trial name
- NCT00951483
- Testing
- Quetiapine-XR
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Loyola University
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Anxiety, Depression
PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness
This is a stepped wedged randomized controlled trial comparing the PARTNER intervention with usual care in 5 Intensive Care Units.
- Trial name
- NCT02445937
- Testing
- PARTNER II
- Where
- 2 sites in United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression, Anxiety
Online Psychological Group Interventions
The aim is to assess the effectiveness of online group CBT for reducing symptoms of depression and anxiety among university students.
- Trial name
- NCT05016154
- Testing
- Online Group CBT intervention, SilverCloud guided, SilverCloud Unguided
- Where
- South Africa
- Volunteers
- 400 people
- Sponsor
- University of Stellenbosch
Depression
Examination of a Soy-Based Supplement for Major Depression
The purpose of this study is to find out if the soy-based dietary supplement Novasoy (Registered Trademark) is effective for the short-term treatment of clinical depression.
- Trial name
- NCT00042380
- Testing
- Novasoy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression in Old Age, Depression, Anxiety
Internet Delivered Psychotherapy for Older Adults
The goal of this mixed-methods, single-arm intervention study is to develop and evaluate a new internet-delivered psychotherapy option called Ger-iPST in older adults with symptoms of depression.
- Trial name
- NCT05739370
- Testing
- Problem-Solving Therapy for Older Adults
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Osteoporosis, Osteopenia
Melatonin Osteoporosis Prevention Study
Osteoporosis is one of the most common skeletal disorders. Today in the United States, 10 million individuals have osteoporosis and 34 million more have low bone mass or osteopenia, which places them at an increased risk of some…
- Trial name
- MOPS (NCT01152580)
- Testing
- melatonin, sugar pill
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Insomnia Chronic, Fecal Microbiota Transplantation
The Efficacy and Safty of FMT in Patients With CID
This clinical trial aims to learn about the efficacy of fecal microbiota transplantation in patients with chronic insomnia disorder.
- Conditions
- Insomnia Chronic, Fecal Microbiota Transplantation, Sleep Disorder, Depression
- Trial name
- NCT05917379
- Testing
- fecal microbiota, synbiotics
- Where
- 7 sites in China
- Volunteers
- 80 people
- Sponsor
- Peking University Sixth Hospital
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