Clinical trials: Anxiety Disorders
Psychosis
Mindfulness, Group Therapy and Psychosis; Training Decreases Anxiety and Depression
The objective of this non-randomized, within-group comparison was to evaluate the addition of mindfulness as a new technique in an outpatient group therapy program for participants diagnosed with a psychotic spectrum disorder…
- Trial name
- NCT04711460
- Testing
- Younger participants, Older participants, TAU
- Volunteers
- 116 people
- Sponsor
- University of Minnesota
Depression, Suicidal Ideation
Screening Wizard- Phase 2
Screening Wizard (SW). Primary Care Providers (PCPs) are often uncertain about how to best refer adolescents who screen positive for depression or suicidality.
- Trial name
- NCT04646369
- Testing
- "screening as usual", Screening Wizard 2.0, Screening Wizard 2.0 + SOVA
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Phobic Disorders
D-Cycloserine to Enhance Cognitive Behavioral Therapy (CBT) for Acrophobia
The purpose of this study is to investigate the utility of post-session administration of D-cycloserine to enhance fear extinction in a sample of people with acrophobia who will be treated with CBT.
- Trial name
- NCT01102803
- Testing
- Individual Cognitive Behavioral Therapy (CBT), D-Cycloserine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Anxiety, Depression
Collaborative Care for Women Veterans
Implementation of Tailored Collaborative Care for Women Veterans (CCWV) was designed to enhance primary care-mental health integration for women Veterans by tailoring services to women Veterans' and providers' needs and providing…
- Conditions
- Anxiety, Depression, Stress Disorders, Post Traumatic
- Trial name
- CCWV (NCT02950961)
- Testing
- Collaborative Care for Women Veterans
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- VA Office of Research and Development
Anxiety Disorders, Generalized Anxiety Disorder
Drug Therapy for Generalized Anxiety Disorder Among the Elderly
This study will determine the efficacy of escitalopram (Lexapro®), an anti-anxiety drug, for generalized anxiety disorder (GAD) and the ways genetics affect response to treatment for GAD in elderly individuals.
- Trial name
- NCT00105586
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Pittsburgh
Obsessive-Compulsive Disorder
A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder
The purpose of this study was to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in participants with Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT04693351
- Testing
- Troriluzole
- Where
- 89 sites in United States, Canada and 5 more
- Volunteers
- 589 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Anxiety Disorder Social, Anxiety
A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder
The goal of this study is to see whether Botox is an effective treatment for social anxiety disorder (SAD). Participants will complete two short surveys on depression and anxiety symptoms, receive a one-time injection of Botox…
- Trial name
- NCT03078270
- Testing
- botulinum toxin A
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Daniel Lieberman
Autism Spectrum Disorder, Quality of Life
Essential Oils for Enhancing QOL in ASD
Essential oils (aromatic oils extracted from plant parts) are routinely used by the public and are available on the market. Investigators are conducting this study because it is unknown whether the essential oils formulations…
- Conditions
- Autism Spectrum Disorder, Quality of Life, Sleep, Anxiety
- Trial name
- NCT02543203
- Testing
- Reconnect, Coconut oil Comparator
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jill Hollway
Depression, Anxiety
A Transdiagnostic Course for Common Mental Health Problems in Primary Care
This study investigates the feasibility of a transdiagnostic course that is intended to work for a large variety of patient groups with clinically significant depression or anxiety in primary care.
- Trial name
- NCT04522713
- Testing
- Behavioral activation, evidence-based sleep strategies including sleep restriction, exposure-based strategies, promotion of physical activity and recuperating activities, psychoeducational material
- Where
- 2 sites in Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Arthritis, Diabetes
Can Mental Health Chatbots Help Chronic Disease Populations?
Past research has shown that patients suffering from chronic health conditions tend to experience high levels of negative mental health symptoms (e.g., depression).
- Conditions
- Arthritis, Diabetes, Depression, Anxiety
- Trial name
- NCT04620668
- Testing
- Wysa
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Luke MacNeill
Medication Adherence, Depressive Symptoms
Testing THRIVE 365 for Black Sexual Minority Men (On The Daily)
The primary goal of this study is to test a minority stress model of psychological health outcomes for Black sexual minority men (BSMM) while using and not using a novel intervention named THRIVE 365.
- Conditions
- Medication Adherence, Depressive Symptoms, Anxiety Symptoms, Emotion Regulation
- Trial name
- OTD (NCT05376397)
- Testing
- iTHRIVE 365
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Hospice, End of Life
Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers
Background: Nature-based virtual reality (VR) and other outdoor experiences in head-mounted displays (HMDs) offer powerful, non-pharmacological tools for hospice teams to help patients undergoing end-of-life (EOL) transitions.
- Conditions
- Hospice, End of Life, Palliative Care, Pain
- Trial name
- NCT06186960
- Testing
- Tandem Virtual Reality
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Obsessive-Compulsive Disorder
Effects of Marijuana on Symptoms of OCD
The purpose of this pilot research study is to test whether certain components of the marijuana plant, known as "cannabinoids", may help to reduce symptoms in patients with OCD.
- Trial name
- ECOS (NCT03274440)
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Depression, Anxiety
IntelliCare in College Students
This study is an 8-week usability and feasibility trial of the smartphone student stress-management app IntelliCare for college students.
- Trial name
- ICCS (NCT04035577)
- Testing
- Mobile self-help intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Gastrointestinal Cancer, Depression
Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers
The goal of this open-label clinical trial is to assess the feasibility of Ketamine-assisted psychotherapy (KAP) studies for adults with non-operable GI cancers suffering with existential distress.
- Conditions
- Gastrointestinal Cancer, Depression, Anxiety
- Trial name
- TREK (NCT06001372)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Utah
Burns, Wound Care
Comparison of Virtual Reality and Passive Distraction on Burn Wound Care Pain in Adolescents
Relief of severe burn wound care pain may require both medications to relieve pain and non-medication interventions,such as distraction. Little is known about distraction's effectiveness.
- Conditions
- Burns, Wound Care, Pain
- Trial name
- NCT01812655
- Testing
- Virtual Reality, Passive Distraction
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Anxiety, Depression
Factorial Optimization Trial to Test Effects of Coping Intervention Components
This study will identify components for inclusion in a coping intervention package to reduce mental health problems among children exposed to high interparental conflict after parental separation/divorce.
- Conditions
- Anxiety, Depression, Coping Skills, Emotional Problem
- Trial name
- NCT05822687
- Testing
- Education, Reappraisal Coping, Distraction Coping
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Arizona State University
Alcohol and Substance-Related Mental Disorders
Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia
This is a randomized controlled trial (RCT) evaluating the effectiveness of a screening, brief intervention, and referral to treatment (SBIRT) stepped-care system in reducing unhealthy AOD use among Congolese refugees and the…
- Trial name
- NCT05471921
- Testing
- SBIRT, Treatment as usual
- Where
- 2 sites in United States, Zambia
- Volunteers
- 400 people
- Sponsor
- Columbia University
Pain, Procedural, Pain, Postoperative
The Effect of Vibration and Cold on Pain and Anxiety Associated With Chest Tube Removal Following CABG
Removal of chest tubes after coronary artery bypass graft (CABG) surgery can cause severe pain and anxiety, which may negatively affect the recovery process.
- Conditions
- Pain, Procedural, Pain, Postoperative, Coronary Artery Bypass Surgery, Chest Tubes
- Trial name
- CABG (NCT06217263)
- Testing
- Vibration device, Vibration device&Cold application pack
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University - Cerrahpasa
Therapeutic Adherence, Nurse-Patient Relations
The Effect of Therapeutic Touch on Sleep and Anxiety
The aim of this study is to determine the effect of the therapeutic touch applied to the sleep patterns of individuals aged 65-85 years with chronic diseases who are treated in the Neurology Intensive Care Unit of Ankara City…
- Conditions
- Therapeutic Adherence, Nurse-Patient Relations, Sleep Disorder
- Trial name
- NCT05363787
- Testing
- therapeutic touch
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- KTO Karatay University