Clinical trials: Anxiety Generalized
Posttraumatic Stress Disorder, Major Depressive Disorder
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
The Royal Canadian Mounted Police (RCMP), like all public safety personnel (PSP), are frequently exposed to potentially psychologically traumatic events that contribute to posttraumatic stress injuries (PTSI).
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05527509
- Testing
- Emotional Resilience Skills Training (ERST), Active Monitoring
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Regina
Depression in Adults, Anxiety Disorder Generalized
ACT for Individuals With MNCD and Their Care Partners
This project aims to implement and evaluate a dyadic intervention (i.e., acceptance commitment therapy) for persons with AD/ADRD and their care partners.
- Conditions
- Depression in Adults, Anxiety Disorder Generalized, Grief
- Trial name
- ACT (NCT07239609)
- Testing
- Acceptance Commitment Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Generalized Anxiety Disorder
A Single-Component CBT for GAD
Generalized Anxiety Disorder (GAD) is a chronic condition that is characterized by excessive and uncontrollable worry and anxiety. In Canada, 3 to 4% of the population suffer from GAD at any point in time.
- Trial name
- NCT02552108
- Testing
- Behavioural experiments for intolerance of uncertainty (BE-IU)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Depression Disorder, Anxiety
Impact of Nut Consumption on Mental Health in Young Adults
Nuts have a high nutrient density, and numerous studies have reported their cardiometabolic benefits. Although observational studies in adults have indicated a potential link between nut consumption and improved mental health…
- Conditions
- Depression Disorder, Anxiety, Mental Health, Stress
- Trial name
- NUTS4BRAIN-RCT (NCT07292610)
- Testing
- mixed nuts. Group A, mixed nuts. Group B, control group
- Where
- Spain
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Anxiety Generalized, Breast Cancer Female
Anti-anxiety Biotics for Breast Cancer Survivors
Cancer survivors experience more rapid declines in health-related quality of life which include physical and psychological comorbidities, the latter of which may be subclinical and often overlooked by primary care providers.
- Trial name
- ABBCS (NCT04784182)
- Testing
- probiotic plus prebiotic supplement
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Auburn University
Generalized Anxiety Disorder, Sleep Disturbances
Mechanisms of Sleep Disturbance in Children With Generalized Anxiety Disorder (GAD)
Anxiety disorders are among the most common mental disorders in children, affecting approximately 1 out of every 10 children and adolescents.
- Trial name
- NCT01032473
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Pregnancy
on General Well-being, Anxiety, and Physical Activity in Pregnant Women
102 pregnant women will be randomly divided into 2 groups. Participants in the control group will be given pregnancy counseling that includes only nutrition, walking (3 days a week for 30 minutes), and breathing exercises, and…
- Trial name
- Qigong (NCT07023978)
- Testing
- Some movements in the qigong study called Ba Duan Jin, which will be applied to pregnant women, will be arranged for pregnant women and explained in detail. These are very slow, movements
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Depression / Major Depressive Disorder, Anxiety
Digital Single-Session Cognitive Behavioural Therapy in Healthy Adults
The goal of this study is to learn if digital single-session cognitive behavioural therapy can treat mental health in adults. The main question it aims to answer is: Does digital single-session cognitive behavioural therapy…
- Conditions
- Depression / Major Depressive Disorder, Anxiety, Anxiety Disorder Generalized
- Trial name
- CBT (NCT07873905)
- Testing
- Digital single-session cognitive behavioural therapy, Digital memory task
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brunel University
Anxiety Disorders
Neurobiology of Generalized Fear-Conditioning & Avoidance in Anxiety Disorders
Anxiety disorders are among the most prevalent, costly, and disabling mental illnesses. One central, yet largely understudied, abnormality in anxiety disorders is the heightened tendency to display fear and avoidance in reaction…
- Trial name
- NCT03033056
- Testing
- Test of fear conditioning
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Separation Anxiety, Anxiety
Reduction of Perioperative Anxiety Using a Hand-held Video Game Device
Distraction techniques, such as use of a virtual reality device, have been used to augment or replace pharmacological practices for relief of anxiety in pediatric patients prior to surgical procedures.
- Conditions
- Separation Anxiety, Anxiety, Anxiety, Separation, Anxiety Generalized
- Trial name
- NCT04950088
- Testing
- Hand-held video game device
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Anxiety Disorders, Social Phobia
Child and Adolescent Anxiety Disorders (CAMS)
This randomized, controlled trial compared the efficacy of the medication sertraline (Zoloft®), cognitive-behavioral therapy, the combination of these treatments, and placebo for youth with anxiety disorders.
- Conditions
- Anxiety Disorders, Social Phobia, Generalized Anxiety Disorder
- Trial name
- NCT00052078
- Testing
- Sertraline (SRT), Cognitive Behavioral Therapy (CBT)
- Where
- 6 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Generalized Anxiety Disorder
Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study
The purpose of this research is to look at the effects of computerized cognitive training on anxiety, sleep, mental abilities (cognition), and other aspects of daytime functioning, such as arousal.
- Trial name
- COGMA (NCT04421690)
- Testing
- Cognitive Training, Trivia Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Generalized Anxiety Disorder
Locating Regions of Interest in Generalized Anxiety Disorder Using Function Magnetic Resonance Imaging (fMRI)
The investigators are seeking to locate the brain regions of interest in generalized anxiety disorder (GAD) using both structural (sMRI) and functional magnetic resonance imaging (fMRI).
- Trial name
- fMRI (NCT01607710)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Generalized Anxiety Disorder, Panic Disorder
Neural Functioning Underlying Anxiety and Its Treatment (The INSULA Study)
This study will examine the effects of cognitive behavioral therapy on brain function in people with anxiety disorders.
- Conditions
- Generalized Anxiety Disorder, Panic Disorder, Anxiety Disorders
- Trial name
- NCT00947570
- Testing
- Cognitive behavioral therapy for anxiety
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Generalized Anxiety Disorder, Social Phobia
Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers
This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety disorders in community health centers.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder
- Trial name
- NCT01416805
- Testing
- Computerized Cognitive Behavioral Therapy, Treatment as usual
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety Disorders, Separation Anxiety Disorder
A Research Study of How Teens With and Without an Anxiety Disorder Make Decisions
The purpose of this trial is to study how teens with and without an anxiety disorder make decisions. This is a brain imaging study using functional magnetic resonance imaging (fMRI) in adolescents between the ages of 13 and 17.
- Conditions
- Anxiety Disorders, Separation Anxiety Disorder, Phobic Disorders
- Trial name
- NCT00104195
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. A parenting intervention for youth with anxiety, called Supportive Parenting of Anxious Childhood Emotions…
- Conditions
- Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Separation Anxiety
- Trial name
- NCT04922502
- Testing
- Standard SPACE, Bibliotherapy, low therapist contact SPACE
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Social Anxiety, Major Depression Mild
Transdiagnostic REBT Prevention Program for Adolescents
Anxiety and depressive disorders are common in adolescents, however they are often unrecognized. Rational emotive behavioral therapy (REBT), a form of cognitive behavioral therapy (CBT) is efficient for children and adolescents.
- Conditions
- Social Anxiety, Major Depression Mild, Panic Disorder, Specific Phobia
- Trial name
- NCT02756507
- Testing
- video-based transdiagnostic REBT, Wait list
- Where
- Romania
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Anorexia Nervosa, Major Depressive Disorder
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or…
- Conditions
- Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT02615119
- Testing
- Isoproterenol, Normal saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Generalized Anxiety Disease
A Phase 1 Study To Estimate The Effects Of PD 0332334 On Lithium Pharmacokinetics In Healthy Subjects
The purpose of this study is to investigate if PD 0332334 affects the pharmacokinetics of lithium by co-administering both drugs to healthy adults.
- Trial name
- NCT00820794
- Testing
- Lithium, PD 0332334
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer