Clinical trials: Anxious-Depressive
PTSD - Post Traumatic Stress Disorder
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more symptoms that might be related to…
- Trial name
- NCT07280065
- Testing
- Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
- Where
- 6 sites in United States, Australia
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
Emotional Disorders, Anxiety
Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled Trial
This adaptive randomized controlled trial evaluates the efficacy of a transdiagnostic, internet-delivered psychological intervention for emotional disorders, tailored to patient´s early clinical response.
- Conditions
- Emotional Disorders, Anxiety, Depression, Unipolar
- Trial name
- NCT07051148
- Testing
- UJI Online Transdiagnostic Protocol, UJI On Line Transdiagnostic Hibrid Protocol
- Volunteers
- 366 people
- Sponsor
- Universitat Jaume I
Anxiety Disorders, Depressive Disorder
Treating Adolescents With CBT and OBH
The purpose of this study is to examine various behavioral, social, and emotional changes that result from engaging in an OBH and CBT treatment program designed for adolescents.
- Conditions
- Anxiety Disorders, Depressive Disorder, Substance Use Disorders
- Trial name
- NCT04760938
- Testing
- Outdoor Behavioral Healthcare (OBH), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Post Traumatic Stress Disorder (PTSD), Anxiety
COVID-Impact "Psychological IMPACT of Covid-19 on AP-HP Staff"
The epidemic of coronavirus induces a major influx of patients implying a rapid modification of the organizations, a work overload and a significant stress for the care teams and supports of the hospitals of the Assistance…
- Conditions
- Post Traumatic Stress Disorder (PTSD), Anxiety, Depression, Epidemic Disease
- Trial name
- Covid-Impact (NCT04558437)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Psychoeducation
Psychoeducational Program for Cancer Patients.
The main objective of the study are: 1. To explore the effectiveness of psychoeducation program for cancer patients who refuse treatment because of irrational fears and anxieties. 2.
- Trial name
- NCT06175195
- Testing
- Psychoeducational Inervention
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Depression, Anxiety Disorders
Effects of Interpersonal Psychotherapy on Depression During and After Pregnancy
This study will evaluate the impact of interpersonal psychotherapy on the course of depression during and after pregnancy, as well as its effect on infant birth outcomes.
- Trial name
- NCT00380419
- Testing
- Interpersonal Psychotherapy (IPT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Asthma, Chest Syndrome
Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant Asthma
Asthma, abbreviation for bronchial asthma, is one of the common chronic airways disease that threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually…
- Conditions
- Asthma, Chest Syndrome, Clinical Anxiety, Clinical Depression
- Trial name
- NCT03237221
- Testing
- Treat patient according to Global Initiative for Asthma (GINA) guideline
- Where
- 34 sites in China
- Volunteers
- 76 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Depressive Disorder and Anxiety Disorders
To Investigate Effects GSK561679 on Part of the Body's System That Controls the Balance of Many of the Hormones.
A study to investigate the effects GSK561679 on part of the body's system that controls the balance of many of the hormones (including cortisol).
- Trial name
- NCT00426608
- Testing
- metyrapone, alprazolam, GSK561679
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pregnancy Related, Mental Health Issue
MamaConecta: Digital Tool for Maternal Mental Health
The goal of this randomized controlled trial is to validate a digital health tool, Dana app, that enhances well-being and supports mental health monitoring for women during the perinatal period.
- Conditions
- Pregnancy Related, Mental Health Issue, Postpartum Depression, Postpartum Anxiety
- Trial name
- DDT (NCT06442774)
- Testing
- Mobile application, Monitoring via wearable
- Where
- 3 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- A Thousand Colibris, S.L
Cancer Survivors
Comparing Multicomponent and Aerobic Training: Impact on Fitness, Psychological and Quality of Life Parameters in Cancer Survivors Patients
The goal of this clinical trial is to evaluate if a multicomponent training program (MCT), including aerobic and resistance exercises, or an aerobic training program (AT) can improve physiological, physical fitness, mental…
- Trial name
- NCT06853613
- Testing
- Multicomponent Training Protocol, Aerobic Training Protocol
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Bari Aldo Moro
Mental Health Issue, Substance Use Disorders
Improving Maternal Mental Health & SUD Screening and Treatment
The purpose of the study is to compare a text message-based mental health and substance use screening and referral to a treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care…
- Conditions
- Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
- Trial name
- NCT05764213
- Testing
- Listening to Women & Pregnant and Postpartum People
- Where
- United States
- Volunteers
- 10,469 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Anxiety Disorders, Depressive Disorder
Big Feelings: A Study on Children's Emotions in Therapy
The goal of this clinical trial is to learn about how psychotherapy works for children and adolescents aged 8 - 15 with anxiety, depression, trauma, or disruptive behaviour.
- Conditions
- Anxiety Disorders, Depressive Disorder, Mood Disorders, Conduct Disorder
- Trial name
- NCT05637320
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma or Conduct Problems
- Where
- 2 sites in Canada
- Volunteers
- 202 people
- Sponsor
- University of Guelph
Anxiety Depression Disorder
Role of Anxio-depressive History on Return to Work and Sport After Rotator Cuff Surgery
Anxiety-depressive disorders are also very frequent, in the form of different pathologies that are often intertwined (prevalence of generalized anxiety disorders in 5% of the population, characterized depressive episodes in 5%…
- Trial name
- Reprise (NCT05531929)
- Where
- France
- Volunteers
- 212 people
- Sponsor
- University Hospital, Strasbourg, France
Anxiety Depression (Mild or Not Persistent), Major Depressive Disorder, Single Episode, Unspecified
Self-Management for Anxiety, Depression and Somatoform Disorders
Anxiety, Depression and Somatoform disorders are highly prevalent in primary care. Very often these conditions remain undiscovered and/or untreated.
- Conditions
- Anxiety Depression (Mild or Not Persistent), Major Depressive Disorder, Single Episode, Unspecified, Neurotic, Stress-related and Somatoform Disorders
- Trial name
- SMADS (NCT01726387)
- Testing
- Psychosocial Counseling, Usual Care
- Where
- Germany
- Volunteers
- 364 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Fibromyalgia
Supervised and Home Training in Fibromyalgia
The goal of this clinical trial is to evaluate the effectiveness of supervised multicomponent training (MCT) on physiological parameters, physical fitness, mental well-being, and quality of life in subjects with a history of…
- Trial name
- NCT06956456
- Testing
- Supervised Multicomponent Training Protocol, Non-Supervised Home-Based Multicomponent Training Protocol
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Bari Aldo Moro
Anorexia Nervosa, Major Depressive Disorder
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or…
- Conditions
- Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT02615119
- Testing
- Isoproterenol, Normal saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Obese Patients (BMI ≥ 30 kg/m²), Anxiety
Therapeutic Potential of a Synbiotic to Improve Mental Health in Subjects With Obesity.
Obese individuals are a particularly vulnerable population for mental health problems, especially depression and anxiety. The aim of this study is to evaluate whether the intake of a synbiotic, composed of prebiotics and…
- Conditions
- Obese Patients (BMI ≥ 30 kg/m²), Anxiety, Depressive Disorder
- Trial name
- NCT06901739
- Testing
- Synbiotic
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Celia Bañuls
Depression - Major Depressive Disorder, Anxiety
AcceXible Speech-Based Screening for Depression and Anxiety in University Students (BUAP, Mexico)
Major depressive disorder (MDD) and anxiety are increasingly prevalent among university student populations, yet early detection remains reliant on psychometric instruments tied to diagnostic criteria (e.g., PHQ-9, GAD).
- Trial name
- NCT07553130
- Testing
- AcceXible
- Where
- Mexico
- Volunteers
- 785 people, healthy volunteers welcome
- Sponsor
- Accexible
Hypertension, Hypertension in Pregnancy
Bridging the Gap From Postpartum to Primary Care
Chronic health conditions affect most older adults. Preventative medicine and risk management strategies, especially when applied earlier in life, are essential to altering the trajectory of a disease and ultimately improving…
- Conditions
- Hypertension, Hypertension in Pregnancy, Diabetes Mellitus, Gestational Diabetes
- Trial name
- NCT05543265
- Testing
- Default appointment scheduling, Targeted messaging, Nudge Reminders
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Massachusetts General Hospital