Clinical trials: Aortic Aneurysm, Abdominal, open to volunteers
Aging, Aortic Aneurysm, Abdominal
The Intersectional Viborg Screening Program: Cost-(Effectiveness) of Screening for Diabetes and Cardiovascular Diseases
This is an intersectional and interdisciplinary screening program in Viborg Municipality, including 67 years old citizens. This observational study will estimate the cost-effectiveness of a combined screening program for the…
- Conditions
- Aging, Aortic Aneurysm, Abdominal, Hypertension, Mass Screening
- Trial name
- VISP (NCT03395509)
- Where
- Denmark
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Central Jutland Regional Hospital
Abdominal Aortic Aneurysm, Arterial Stiffness
EndoVascular Aneurysm Repair: Heart Remodeling and Aortic Stiffness Study
Abdominal aortic aneurysm (AAA) is associated with a high burden of cardiovascular morbidity and mortality. Although endovascular aneurysm repair (EVAR) has become the preferred treatment for many patients with infrarenal AAA…
- Conditions
- Abdominal Aortic Aneurysm, Arterial Stiffness, Left Ventricle Remodeling
- Trial name
- EVAR-HRAS (NCT07722793)
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Aortic Aneurysm, Thoracoabdominal
Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA
The primary clinical objective of this study is to evaluate the safety and effectiveness of a physician-modified, fenestrated and branched aortic endoprosthesis for the treatment of thoracoabdominal aortic aneurysms (TAAAs).
- Trial name
- NCT02989948
- Testing
- Physician-modified aortic endograft
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm
Zenith® Fenestrated+ Clinical Study
The Zenith® Fenestrated+ Endovascular Graft Clinical Study will assess the safety and effectiveness of the Zenith® Fenestrated+ Endovascular Graft (ZFEN+) in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent…
- Conditions
- Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm, Extent IV Thoracoabdominal, Pararenal Aneurysm
- Trial name
- NCT04875429
- Testing
- Zenith Fenestrated+ Endovascular Graft in combination with the BeGraft Balloon-Expandable FEVAR Bridging Stent Graft System and Unibody2
- Where
- 33 sites in United States, United Kingdom
- Volunteers
- 105 people
- Sponsor
- Cook Research Incorporated
Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting
Frailty and Physician Modified Fenestrated Endograft for Thoracoabdominal Aortic Pathologies
The primary objective of this single arm, prospective feasibility study, Impact of Frailty on Clinical Outcomes of Patients Treated for Thoracoabdominal and Complex Abdominal Aortic Aneurysms with Physician-Modified Fenestrated…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting, Pararenal Aneurysm, Frailty Syndrome
- Trial name
- NCT04524247
- Testing
- Physician Modified Endografts
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Abdominal Aortic Aneurysm Without Rupture
Efficacy of Biomarkers and CEUS Versus CTA in AAA Follow-up Post-EVAR
This prospective observational study evaluates the efficacy of contrast-enhanced ultrasound and biomarker determination in the follow-up of patients with abdominal aortic aneurysm (AAA) treated with Endovascular Aneurysm Repair…
- Trial name
- EVAR-markers (NCT06866769)
- Testing
- CTA
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Complex Abdominal Aortic Aneurysms
Clinical Performance and Safety Assessment of the Use of iCover Balloon Expandable Covered Stent (iVascular) Implanted as Bridging Stent in FEVAR (Fenestrated Endovascular Aortic Repair) for the Treatment of Complex Abdominal Aortic Aneurysms
fenCo is a European multicentre, prospective study to evaluate the use of the iCover covered stents as bridging stents for reno-visceral target vessel during fEVAR for the treatment of complex abdominal aortic aneurysms.
- Trial name
- fenCo (NCT07529275)
- Testing
- iCover balloon-expandable covered peripheral stent system as bridging stent
- Where
- 24 sites in Belgium, France and 3 more
- Volunteers
- 165 people
- Sponsor
- iVascular S.L.U.
Thoracoabdominal Aortic Aneurysms
Safety and Efficacy of a Multi-branched Thoracoabdominal Stent Graft System for Thoracoabdominal Aortic Aneurysm.
Evaluation of the safety and efficacy of a multi-branched thoracoabdominal stent graft system for thoracoabdominal aortic aneurysm.
- Trial name
- NCT05054985
- Testing
- Multi-Branched Thoracoabdominal Stent Graft System
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
TAAA, AAA - Abdominal Aortic Aneurysm
Data Collection of the TUVA BX and iCover Stent Grafts Implanted During Branched Endovascular Aortic Repair (BEVAR)
The study aims to check whether the TUVA BX and iCover stent grafts are safe and work well when used during a specific type of minimally invasive surgery (BEVAR) to treat complex aortic aneurysms.
- Trial name
- NCT07540507
- Testing
- Endovascular Aortic Repair
- Where
- Netherlands
- Volunteers
- 105 people
- Sponsor
- JOTEC GmbH
Abdominal Aortic Aneurysm
Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms
The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA).
- Trial name
- AAA-MRE (NCT02387255)
- Testing
- Resoundant Driver System
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Aortic Aneurysm, Thoracoabdominal, Aortic Diseases
Standardized Physician-modified Fenestrated Endograft Registry
Multicenter retrospective study including all consecutive patients treated by PMEG using a standard modification technique of Valiant Captivia (Medtronic, Minneapolis, MN-USA).
- Trial name
- SPHERE (NCT06358248)
- Testing
- Physician-modification of Valiant Captivia Endograft (Medtronic, Minneapolis, MN-USA).
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University Hospital Padova
Abdominal Aortic Aneurysm
Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)
This research study is being conducted to test how an imaging drug called 64Cu-DOTA-ECL1i can be used to image an abdominal aortic aneurysm.
- Trial name
- NCT07548099
- Testing
- 64Cu-DOTA-ECL1i
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aortic Aneurysm, Abdominal, Thoracic Aneurysm
Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex AAAs Using Fenestrated- Branched Devices
The purpose of this study is to assess the clinical outcomes and radiation of the use of off-the-shelf and custom-made devices (CMDs) for the endovascular repair of juxtarenal, suprarenal, thoracoabdominal and arch aortic…
- Trial name
- NCT02266719
- Testing
- Fenestrated CMD, Type I - III TAAA, Arch cohort
- Where
- 4 sites in United States
- Volunteers
- 750 people
- Sponsor
- Carlos Timaran
Aortic Aneurysm, Abdominal
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
The aim of this randomized study is to compare the safety and performance of EndoVascular Aneurysm Repair with ESAR using Endurant + Heli-FX™ EndoAnchor™ system and FEVAR using customizable grafts from Cook (Zenith Fenestrated…
- Trial name
- SOCRATES (NCT04503395)
- Testing
- ESAR treatment: Endograft + Heli-FX Endoanchor, FEVAR treatment : Fenestrated endograft
- Where
- 33 sites in United States, Austria and 8 more
- Volunteers
- 204 people
- Sponsor
- FCRE (Foundation for Cardiovascular Research and Education)
Thoracoabdominal Aortic Aneurysm, Cardiopulmonary Bypass
CompaRison of FEmorofemoral Bypass and Left-Heart ByPass Techniques in Open Thoracoabdominal AortIc Aneurysm Repair
The study is a multicenter, two-arm, open-label, randomized, parallel-controlled trial, which plans to enroll 236 participants diagnosed with TAAA from 4 hospitals in China.
- Conditions
- Thoracoabdominal Aortic Aneurysm, Cardiopulmonary Bypass, Open Repair
- Trial name
- REPAIR (NCT07518251)
- Testing
- Thoracoabdominal aortic aneurysm repair under fCPB, Thoracoabdominal aortic aneurysm repair under LHB
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Beijing Anzhen Hospital
Abdominal Aortic Aneurysm
Screening for Abdominal Aortic Aneurysms in the General Practice by Ultraportable Ultrasound
Abdominal aortic aneurysm (AAA) is a localized dilatation of a segment of the aorta artery in its abdominal portion. It affects 1.7% of men aged 65 years and older.
- Trial name
- DACEP (NCT05617326)
- Testing
- AAA screening by a GP, AAA screening by a radiologist
- Where
- 6 sites in France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Breast Cancer, Bowel Cancer
EQUITA - A Feasibility Trial of a Faith-placed Intervention to Increase Screening Uptake in Black Adults
The goal of this randomised feasibility trial is to examine feasibility and acceptability of a co-produced and faith-placed intervention to increase uptake of breast, cervical, bowel, and abdominal aortic aneurysm (AAA) screening…
- Conditions
- Breast Cancer, Bowel Cancer, Cervical Cancer, Abdominal Aortic Aneurysm
- Trial name
- EQUITA (NCT06981182)
- Testing
- Faith-placed intervention to promote breast, cervical, bowel, and AAA screening uptake in Black communities.
- Where
- 3 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sunderland
Abdominal Aortic Aneurysm
Poland-Italy Aortic Research Bridge Real World Registry
Objective To pragmatically collect and analyze patient-level clinical, procedural, and outcome data from participating centers in Italy and Poland on the use of the PERCUTEK Tycheseal™ stent-graft system for the endovascular…
- Trial name
- POWER (NCT07476196)
- Where
- 26 sites in Italy, Poland
- Volunteers
- 200 people
- Sponsor
- American Heart of Poland
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Enlargement
Italian Multicenter Database for Open Conversions After EVAR
Late endovascular abdominal aneurysm repair (EVAR) complications not amenable to endovascular correction can undergo either late open conversion (LOC) or semi-conversion (SC).
- Trial name
- iConveRt (NCT04299984)
- Testing
- Open Conversion after EVAR, SemiConversion after EVAR
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Aneurysm Abdominal, Arterial Aneurysm
Italian Multicentric Study on the Treatment of Visceral Aneurysms With the Flow Diversion Stent Derivo Peripher and Derivo 2
This is a multicentric voluntary observational study with a retrospective evaluation of prospectively collected data concerning the treatment of visceral aneurysms with flow diversion stent Derivo Peripher and Derivo 2 (DED…
- Trial name
- DEDICATE (NCT06325371)
- Testing
- Visceral aneurysm stenting
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Turin, Italy