Clinical trials: Aortitis
Takayasu's Arteritis, Giant Cell Arteritis
Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis and to determine if patients…
- Conditions
- Takayasu's Arteritis, Giant Cell Arteritis, Arteritis, Vasculitis
- Trial name
- NCT01795456
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Giant Cell Arteritis
Tocilizumab Dose-tapering and Interruption in Patients With Giant Cell Arteritis Achieving the Clinical Remission.
Interleukin-6 (IL-6), a pro-inflammatory cytokine, has been found to have a crucial role in the pathogenesis of Giant cel arteritis (GCA).
- Trial name
- NCT03244709
- Testing
- Tocilizumab
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Hospital of Prato
Aortitis
VCRC Longitudinal Protocol for Aortitis
The term 'aortitis' refers to inflammation of the aorta. Aortitis is known to occur in a variety of vasculitides and connective tissue diseases, such as giant cell arteritis (GCA), Takayasu arteritis (TAK), rheumatoid arthritis…
- Trial name
- NCT03022331
- Where
- 10 sites in United States, Canada
- Volunteers
- 16 people
- Sponsor
- University of Pennsylvania
Retroperitoneal Fibrosis, Autoimmune Pancreatitis
Rituximab in IgG4-RD: A Phase 1-2 Trial
The primary objective of this study is to evaluate the safety and effectiveness of rituximab in IgG4-RD.
- Conditions
- Retroperitoneal Fibrosis, Autoimmune Pancreatitis, Sialadenitis, Pseudotumor
- Trial name
- NCT01584388
- Testing
- Rituximab
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Aortitis, Cutaneous Vasculitis
VCRC Tissue Repository
The purpose of this study is to collect existing tissue specimens from subjects enrolled in Vasculitis Clinical Research Consortium (VCRC) studies.
- Conditions
- Aortitis, Cutaneous Vasculitis, Eosinophilic Granulomatosis With Polyangiitis, Giant Cell Arteritis
- Trial name
- NCT02967068
- Where
- 8 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- University of Pennsylvania
Aortitis, Vascular Graft Infection
VIP - Vascular Infection Project
Constitution of a prospective multicentric observational database to study vascular infections, both native, especially aortitis, and vascular graft and endograft infections.
- Conditions
- Aortitis, Vascular Graft Infection, Blood Vessel Prosthesis, Infections
- Trial name
- Cohorte VIP (NCT06866535)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Bordeaux
Aortitis, Giant Cell Arteritis (GCA)
TocILizumab in aorTitis in GCA (TILT)
This is a french multicenter observational study assessing safety and efficacy of biosimilar of Tocilizumab in Giant Cell Arteritis (GCA) with active aortitis, including 14 reference centers from the Groupe d'Etude Français des…
- Trial name
- TILT (NCT06271018)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Groupe français d'étude des Maladies Inflammatoires de loeil
Vascular Graft Infection, Infectious Aortitis
China Aortic Infection and Graft Infection Study: An Ambispective Cohort
Vascular infections are uncommon but severe infections involving the arterial wall, vascular grafts, or endografts, and their diagnosis and management remain challenging.
- Conditions
- Vascular Graft Infection, Infectious Aortitis, Aortoenteric Fistula
- Trial name
- CAIGIS (NCT07847346)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Idiopathic Aortitis, Retroperitoneal Fibrosis
Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria
Inflammatory aortitis probably represents a heterogeneous group, and the clinical experience accumulated over the last ten years, shared by the experts of the subject, is that the initial clinical, biological or radiological…
- Trial name
- NCT03133949
- Testing
- Establish the clinical, biological and radiological characteristics of patients
- Where
- France
- Volunteers
- 210 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens