Clinical trials: Aphasia, Acquired
Aphasia, Acquired, Language Disorders
Enhancing Language Function in Aphasia
Aphasia is an acquired impairment of language, that commonly results from damage to language areas in the brain (typically the left side of the brain).
- Conditions
- Aphasia, Acquired, Language Disorders, Primary Progressive Aphasia, Stroke, Cerebrovascular
- Trial name
- NCT05443633
- Testing
- individualized speech-language training, standard language intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Aphasia, Apraxia of Speech
Treatments of Acquired Apraxia of Speech
This study was designed to examine the effects of speech therapy on ability to produce speech sounds in persons with acquired apraxia of speech.
- Conditions
- Aphasia, Apraxia of Speech, Stroke
- Trial name
- Apraxia (NCT01483807)
- Testing
- Sound Production Treatment - Blocked, Sound Production Treatment - Random
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Aphasia, Acquired, Stroke
Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia
The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of…
- Conditions
- Aphasia, Acquired, Stroke, Healthy Aging
- Trial name
- sentence (NCT06405594)
- Testing
- Language Condition
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Aphasia, Acquired
Clinic and Neurophysiology of Aphasia Treatment
In the planned study, clinical and electrophysiological features of aphasia recovery in stroke patients are investigated.
- Trial name
- AphasRehab (NCT05572385)
- Testing
- CIAT + Conventional neurorehabilitative therapy
- Volunteers
- 40 people
- Sponsor
- Klinik Bavaria
Aphasia, Acquired, Aphasia
Aphasia Physical EXercise Study: Randomized Trial
The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia.
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia, Non-fluent
- Trial name
- APEX (NCT07281313)
- Testing
- High-intensity physical exercise, Low-intensity physical exercise
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, Berkeley
Aphasia, Acquired, Stroke
Rehabilitation of Post-stroke Aphasia by Targeting Phonological, and Lexico-semantic Deficits With Speech Output Tasks
Aphasia in brain-damaged adult patients refers "to the more or less complete loss of the ability to use language" resulting from acquired brain damage, typically of the left hemisphere.
- Conditions
- Aphasia, Acquired, Stroke, Anomia
- Trial name
- PHOLEXSEM (NCT06451731)
- Testing
- PHOLEXSEM, PACE
- Volunteers
- 44 people
- Sponsor
- Istituto Auxologico Italiano
Aphasia, Acquired, Stroke
Impact of Group Participation on Adults With Aphasia
The purpose of the study is to examine the impact of group participation on adults with aphasia. Participants will complete a standard pre-and post-assessment of language abilities (speech, comprehension, reading, and/or…
- Conditions
- Aphasia, Acquired, Stroke, Rehabilitation, Language Disorder, Acquired
- Trial name
- NCT05520528
- Testing
- Language intervention with group sessions and independent tasks with emphasis on improving reading and writing skills among persons with aphasia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arkansas
Aphasia, CVA
Treatment Intensity - Apraxia of Speech
A growing neurorehabilitation literature suggests that intense treatment may be desired to maximize the effects of therapy following neurologic injury.
- Conditions
- Aphasia, CVA, Apraxia of Speech
- Trial name
- NCT02332915
- Testing
- Sound Production Treatment (SPT)
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Aphasia, Acquired
Virtual Reality in Aphasia Telerehabilitation
The main purpose of this study is to evaluate the use of the immersive 3D HMD VR technology in the language intervention with a home-based telerehabilitation approach for people with aphasia.
- Trial name
- NCT04828759
- Testing
- VR-treatment, Treatment as usual
- Volunteers
- 20 people
- Sponsor
- University of Oulu
Aphasia, Acquired, Stroke, Acute
Neolexon® Aphasia-App in Acute Aphasia After Stroke
Up to now there is proven evidence of traditional logopedic therapy in aphasia, but recent computer-based algorithms also showed their evidence so far.
- Trial name
- Lexi (NCT04080817)
- Testing
- Neolexon, Speech therapy, Self training
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Stroke, Brain Injuries
Clinical Effectiveness of iReadMore for People With Alexia
iReadMore will provide an app-based therapy for people with pure or central alexia. This study aims to test the clinical effectiveness of iReadMore for improving reading accuracy and speed in real world users of the therapy.
- Conditions
- Stroke, Brain Injuries, Aphasia, Alexia
- Trial name
- NCT04849091
- Testing
- iReadMore
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Aphasia, Stroke
Dosage and Predictors of Naming Treatment Response in Aphasia
This study examines aphasia treatment response among Veterans and non-Veterans living with aphasia. It seeks to identify cognitive and neural factors which are predictive of positive response to treatment targeting naming…
- Trial name
- NCT02005016
- Testing
- Naming therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Aphasia, Apraxia of Speech
Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech
The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural…
- Conditions
- Aphasia, Apraxia of Speech, Dysarthria
- Trial name
- NCT04604444
- Testing
- Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Stroke, Aphasia, Acquired
tACS to Enhance Language Abilities
The goal of this study is to see if transcranial alternating current stimulation (tACS) can be used to enhance language abilities in people with post-stroke aphasia.
- Conditions
- Stroke, Aphasia, Acquired, Aphasia
- Trial name
- NCT06092814
- Testing
- Active transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aphasia, Stroke
Multimodal Treatment of Phonological Alexia: Behavioral & fMRI Outcomes
This study offers 90-120 hours of 1:1 training to improve reading skills in adults who have poor reading skills following a stroke.
- Conditions
- Aphasia, Stroke, Dyslexia, Acquired
- Trial name
- NCT00827268
- Testing
- One-on-one treatment of reading difficulties
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Dyslexia, Acquired, Brain Injuries
Therapy for Reading Problems in Adults After Brain Injury
Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.
- Conditions
- Dyslexia, Acquired, Brain Injuries, Cerebrovascular Accident
- Trial name
- NCT00064805
- Testing
- Cognitive Therapy to Improve Reading
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)