Clinical trials: Aphasia, Rehabilitation
Stroke
Speech Therapy for Aphasia: Comparing Two Treatments
This is a behavioral speech therapy trial for individuals who have suffered a stroke on the left side of the brain and have difficulty speaking.
- Trial name
- PMvSFA (NCT02153710)
- Testing
- Semantic Feature Analysis therapy, Phonomotor Therapy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- VA Office of Research and Development
Aphasia, Spatial Neglect
Prism Adaptation in Left Brain Stroke
Of the 15,000 Veterans who are hospitalized for stroke each year more than half experience spatial and motor impairments and pain.
- Conditions
- Aphasia, Spatial Neglect, Stroke
- Trial name
- NCT04387162
- Testing
- Prism Adaptation Treatment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- VA Office of Research and Development
Aphasia, CVA
Treatment Intensity - Apraxia of Speech
A growing neurorehabilitation literature suggests that intense treatment may be desired to maximize the effects of therapy following neurologic injury.
- Conditions
- Aphasia, CVA, Apraxia of Speech
- Trial name
- NCT02332915
- Testing
- Sound Production Treatment (SPT)
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Broca's Aphasia
Virtual Reality Based Sensorimotor Speech Therapy
The purpose of this study is to determine whether VR based language rehabilitation scenario based on the core premises of ILAT has a beneficial effect on the linguistic performance (faster retrieval of the target lexicon and…
- Trial name
- NCT02928822
- Testing
- VR-based sensorimotor aphasia therapy, Control Group (conventional aphasia rehabilitation)
- Where
- 2 sites in Spain
- Volunteers
- 18 people
- Sponsor
- Universitat Pompeu Fabra
Aphasia, Apraxia of Speech
Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech
The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural…
- Conditions
- Aphasia, Apraxia of Speech, Dysarthria
- Trial name
- NCT04604444
- Testing
- Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Anomia, Aphasia
Cognitive Therapy to Improve Word Finding
Adults who sustain brain damage due to stroke, traumatic injury or surgery may develop difficulty finding words. This study compares the effectiveness of two behavior-based programs to improve picture naming ability in these…
- Conditions
- Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
- Trial name
- NCT00494520
- Testing
- Errorful training condition, Errorless training condition
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Georgetown University
Aphasia
Aphasia Therapy: Factors of Efficacy
Constraint-induced aphasia therapy (CIAT) has proven effective in stroke patients. It has remained unclear, however, whether intensity of therapy or constraint is the relevant factor.
- Trial name
- NCT02804412
- Testing
- Control group, CIAT-group, communication treatment group (CTG)
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
Aphasia
NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery
The current standard of care for rehabilitation of patients with aphasia after stroke is conventional speech and language therapy (SLT).
- Trial name
- NORTHSTAR (NCT02020421)
- Testing
- rTMS, tDCS
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 63 people
- Sponsor
- Dr. Alexander Thiel
Aphasia
Efficacy of Telerehabilitation in the Patients With Aphasia
The study will invite 30 patients to join, and they will be arranged in the face to face group and telerehabilitation group randomly.
- Trial name
- NCT02694133
- Testing
- Smart Phone Based Assistive Speech Therapeutic System, Mobile phone-based tele rehabilitation program
- Volunteers
- 4 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Aphasia, Aphasia Following Cerebral Infarction
Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)
The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired…
- Conditions
- Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired, Aphasia, Rehabilitation
- Trial name
- NCT07036406
- Testing
- Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Teachers College, Columbia University
Aphasia Primary Progressive
Characterisation of Primary Progressives Aphasias
Primary progressive aphasias (PPA) represent a challenging group of degenerative language diseases that has led to growing interest in the scientific and medical community.
- Trial name
- CAPP (NCT02297035)
- Testing
- Behavioural testing, Brain imaging, Genetic screening
- Where
- France
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aphasia, Language Disorders
Evaluation of the Effects of Response Elaboration Training for Aphasia
The purpose of this study is to evaluate the effects of Response Elaboration Training (RET), which is a speech/language therapy for aphasia.
- Conditions
- Aphasia, Language Disorders, Speech Disorders
- Trial name
- NCT00125216
- Testing
- Response Elaboration Training
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Aphasia
Web-Based Treatment for Aphasia
This prospective randomized clinical trial implements an innovative broadband web-based treatment program for individuals with chronic aphasia, and evaluates its efficacy.
- Trial name
- Web-ORLA (NCT04413136)
- Testing
- Web-ORLA, Control
- Volunteers
- 35 people
- Sponsor
- Shirley Ryan AbilityLab
Non Fluent Aphasia in Subacute Stroke
Dual Hemisphere rTMS for Rehabilitation of Post Stroke Aphasia
To investigate the therapeutic effect of dual hemisphere repetitive transcranial magnetic stimulation (rTMS) on post-stroke non fluent aphasia.
- Trial name
- NCT01850836
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stroke, Aphasia
Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy
This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language.
- Trial name
- NCT06891638
- Testing
- Schedule of tDCS administration
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Aphasia
The Effect of Transcranial Direct Current Stimulation and Speech Language Therapy to Improve Language Functioning in Arabic Speakers With Aphasia Post-Stroke
The current planned study is a prospective randomized double-blind, sham-controlled, two parallel-groups, polycentric, phase-I superiority type of trial.
- Trial name
- tES-AR-APHASIA (NCT04644718)
- Testing
- Transcranial direct current stimulation (tDCS)
- Volunteers
- 64 people
- Sponsor
- Imam Abdulrahman Al Faisal Hospital
Aphasia
Efficacy of Low-frequency rTMS in Aphasia
In a randomized controlled trial, efficacy of low-frequency, inhibitory rTMS will be examined in rehabilitation of acquired aphasia.
- Trial name
- NCT05450341
- Testing
- rTMS over right frontal target, rTMS over right temporal target
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Aphasia, Stroke
Implementing Transcranial Direct Current Stimulation in a Rehabilitation Setting
This study looks at whether transcranial Direct Current Stimulation (tDCS) can be effectively implemented in inpatient and outpatient rehabilitation settings during routine speech therapy for people who recently had a stroke and…
- Trial name
- tDCS implement (NCT07535788)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Stroke, Aphasia
Efficacy of START (Startle Rehabilitation Therapy) in the Treatment Stroke-induced Aphasia/Apraxia
A stratified, parallel-group, double-blind, randomized controlled trial of remotely delivered START treatment to individuals with severe-to-moderate stroke (with recruitment focused on individuals with low SES) will be conducted.
- Conditions
- Stroke, Aphasia, Apraxia of Speech
- Trial name
- START (NCT04816799)
- Testing
- Startle Adjuvant Rehabilitation Therapy (START)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Arizona State University
Aphasia, Cerebrovascular Accident
Role of the Right Brain in Recovery of Language Function in Chronic Stroke
This study will examine in healthy individuals and in patients with aphasia (a language disturbance that is usually caused by stroke, brain disease, or injury) which parts of the brain are involved in naming everyday objects.
- Trial name
- NCT00076479
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)