Clinical trials: Apraxia of Speech
Specific Developmental Disorders of Speech and Language, Specific Learning Disorder
Ambulatory Screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
To evaluate, in primary care, the sensitivity of Heterophory-Vertical-Labile (HV-Labile) in ambulatory screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
- Conditions
- Specific Developmental Disorders of Speech and Language, Specific Learning Disorder, Dyslexia, Developmental, Developmental Coordination Disorder
- Trial name
- TDys (NCT04122820)
- Testing
- Diagnostic of specific learning disabilities or of Developmental Coordination Disorder
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- CNGE IRMG Association
Aphasia, Apraxia of Speech
MIRAA - Implementation of Intensive Rehabilitation of Aphasia and/or Apraxia of Speech in Swedish Healthcare
Positive outcomes have been shown following intensive treatment of speech and/or language impairment post stroke, but how to design intensive treatment programs to achieve optimal recovery and neuroplasticity changes needs to be…
- Conditions
- Aphasia, Apraxia of Speech, Stroke
- Trial name
- MIRAA (NCT04957225)
- Testing
- MIRAA (Multimodal Intensive Rehabilitation of Aphasia and Apraxia of speech)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Childhood Apraxia of Speech
The Effects of Caregiver Training on DTTC Treatment Outcomes in CAS
The goal of this clinical trial is to investigate the impact of direct vs. indirect caregiver training on treatment outcomes following a period of Dynamic Temporal and Tactile Cueing (DTTC) intervention combined with home…
- Trial name
- DTTC (NCT05916222)
- Testing
- Dynamic Temporal and Tactile Cueing (DTTC)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- New York University
Apraxia, Oral, Apraxia of Speech
Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech
Treatment of post-stroke apraxia of speech (AOS) requires frequent and ongoing practice with a speech-language pathologist to facilitate lasting behavioral change, which is costly and, therefore, inaccessible to many patients.
- Trial name
- MI-TEE (NCT06467136)
- Testing
- Sound production treatment, Motor Imagery Practice
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Central Florida
Stroke, Dysarthria
Deep Brain Stimulation + Therapy for Stroke
The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabilitation in individuals who have experienced a stroke and have…
- Conditions
- Stroke, Dysarthria, Apraxia, Dysphagia
- Trial name
- NCT07849114
- Testing
- Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pirondini, Elvira, PhD
Childhood Apraxia of Speech, Verbal Apraxia
Role of Omega-DEK in Childhood Apraxia of Speech
This is a 20-week study for children between 3 and 6 years old with confirmed childhood apraxia of speech (CAS). The study includes a 12-week open-label pilot feasibility study of an investigational drug (Omega-DEK) plus…
- Conditions
- Childhood Apraxia of Speech, Verbal Apraxia, Autism
- Trial name
- NCT07216001
- Testing
- Omega-DEK, L-carnitine
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Claudia R. Morris
Childhood Apraxia of Speech
Dose Frequency RCT on DTTC in Children With CAS
Childhood apraxia of speech (CAS) is a pediatric motor-based speech sound disorder that requires a specialized approach to intervention (Maas et al., 2014).
- Trial name
- NCT05675306
- Testing
- Dynamic Temporal and Tactile Cueing Treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marquette University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
PPA, Primary Progressive Aphasia
PiB PET Scanning in Speech and Language Based Dementias
The study is designed to determine whether there are clinical features that can be used as biomarkers to predict whether underlying Alzheimer's pathology is the cause of a speech and language based dementia.
- Conditions
- PPA, Primary Progressive Aphasia, Aphasia, Non-fluent Aphasia
- Trial name
- NCT01623284
- Testing
- C-11 PiB, F-18 FDG
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Mayo Clinic
Apraxia of Speech
Searching of Apraxia of Speech in Children With Specific Language Impairment
Searching of Apraxia of Speech in Children with Specific Language Impairment
- Trial name
- NCT05584033
- Testing
- Mansora Arabic test battery for childhood apraxia of speech
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Aphasia, Apraxia of Speech
taVNS for Speech and Language Recovery in Aphasia
The goal of this research study is to evaluate a novel approach to improving speech recovery in those with acquired apraxia of speech.
- Trial name
- NCT07563387
- Testing
- taVNS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Childhood Apraxia of Speech
Treating Childhood Apraxia of Speech
The study will test two modifications to speech therapy for 40 school-age children with childhood apraxia of speech to determine how to improve treatment outcomes.
- Trial name
- NCT03238677
- Testing
- Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Syracuse University
Speech Sound Disorder, Apraxia of Speech
Efficacy of an Intervention for the Children With Severe Speech Sounds Disorders
Speech sound disorders (SSDs) is one type of communication problems in children. It is a board term describing different difficulties that impact speech intelligibility.
- Conditions
- Speech Sound Disorder, Apraxia of Speech, Developmental Verbal Dyspraxia
- Trial name
- NCT03700151
- Testing
- Treatment for Children with Severe Speech Sound Disorders
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Apraxia of Speech
Using tDCS in Speech-based Stroke Rehabilitation
The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation.
- Trial name
- NCT03452202
- Testing
- Soterix 1x1 line tDCS low-intensity stimulator
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Cerebral Palsy, Hydrocephalus
Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries
This protocol is designed to enable access to intravenous infusions of banked umbilical cord blood (CB), that is thawed and not more than minimally manipulated, for children with various brain disorders.
- Conditions
- Cerebral Palsy, Hydrocephalus, Apraxia of Speech, Hypoxia Ischemia, Cerebral
- Trial name
- NCT03327467
- Testing
- Cord Blood Infusion
- Where
- United States
- Sponsor
- Joanne Kurtzberg, MD
Primary Progressive Aphasia, Apraxia of Speech
Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area and left inferior frontal gyrus)…
- Trial name
- NCT05368350
- Testing
- high-definition transcranial direct current stimulation (HD-tDCS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas at Dallas
Childhood Apraxia of Speech
Motor-based Intervention for Childhood Apraxia of Speech: DTTC-Connect
Childhood apraxia of speech (CAS) is a complex motor speech disorder that significantly limits a child's ability to communicate in daily activities, with difficulties often persisting into adolescence and adulthood.
- Trial name
- NCT07526246
- Testing
- Dynamic Temporal and Tactile Cueing - Connect (DTTC-Connect)
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- New York University
Aphasia, Stroke
Brain Biomarkers of Response to Treatment for Apraxia of Speech
The study will use MRI brain imaging to identify brain changes associated in stroke patients after they receive speech-language treatment for their speech difficulties.
- Trial name
- SPT (NCT02046941)
- Testing
- Speech Production Treatment
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Autism Spectrum Disorder, Apraxia of Speech
Video Assisted Speech Technology to Enhance Motor Planning for Speech
Nearly 3.5 million Americans are diagnosed with Autistic Spectrum Disorder (ASD), a communication disorder that causes skill limitations in the areas of language acquisition, sensory integration, and behavior.
- Trial name
- VAST (NCT04764539)
- Testing
- Video Assisted Speech Therapy (VAST)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- iTherapy, LLC
Childhood Apraxia of Speech
Methylphenidate in Childhood Apraxia of Speech
The purpose of this study is to describe the possible effects of methylphenidate (MPH) on speech intelligibility in children with childhood apraxia of speech (CAS) aged 6-12 years.
- Trial name
- NCT05185583
- Testing
- Methylphenidate Hydrochloride
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- Murdoch Childrens Research Institute