Clinical trials: Arachnophobia
Specific Phobia, Arachnophobia
Use of Safety Behaviors in Exposure Therapy for Arachnophobia
This study examines the impact of safety behaviors (i.e., unnecessary protective actions) on outcomes of exposure therapy for spider phobia.
- Conditions
- Specific Phobia, Arachnophobia, Spider Phobia
- Trial name
- NCT04470882
- Testing
- Exposure with faded safety behaviors, Exposure without safety behaviors, Exposure with unfaded safety behaviors
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Nevada, Reno
Arachnophobia, Phobia
TMS and Exposure Therapy
Spider phobia is an exceedingly common phobia throughout the world. The current standard treatment involves exposure therapy, which consists of a series of brief exposures of an individual to the thing they fear, in this case…
- Trial name
- NCT04019054
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Phobias
fMRI Study Examining Effects of D-cycloserine in Specific Phobia
The research team hopes to use brain imaging and mental testing to learn more about specific phobias and the treatment of phobia.
- Trial name
- NCT00591825
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Specific Phobia, Cognitive-behavioral Therapy
Virtual Reality Exposure in Spider Phobia
While knowledge on the neurobiological signatures of fear and anxiety disorders and, in particular, their association with treatment outcome is accumulating, clinical translation still awaits empirical proof of evidence.
- Conditions
- Specific Phobia, Cognitive-behavioral Therapy, Virtual Reality
- Trial name
- NCT03208400
- Testing
- virtual reality exposure
- Where
- 2 sites in Germany
- Volunteers
- 338 people
- Sponsor
- Julius-Maximilians University
Spider Fear, Arachnophobia
Optimizing Exposure Using Occasional Aversive Imagery in Spider Fearful Individuals
The effectiveness of an optimized extinction training is investigated in spider-fearful individuals. Participants will undergo a one-session standardized extinction training, either with or without occasional metal imagination of…
- Trial name
- NCT05424250
- Testing
- occasional aversive imagination, Exposure
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Philipps University Marburg
Spider Phobia
Gamification in the Treatment of Spider Phobia
Mobile applications are more and more considered when implementing programs for treating mental disorders. The study aims to reduce avoidance and fear of spiders in spider-fearful individuals by combining exposure principles with…
- Trial name
- NCT04423783
- Testing
- 7-day exposure therapy via self-developed app according to (Haberkamp et al., submitted), Therapist-guided one-session online exposure therapy according to (Öst, 1989)
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Anke Haberkamp
Individuals With Fear of Spiders
Neural Activations During Imaginal Exposure in Individuals Fearful of Spiders
This study explores the brain basis of imaginal exposure, a widely used psychological treatment technique. Specifically, this study uses functional magnetic resonance imaging to examine brain areas activated during imaginal…
- Trial name
- NCT03969160
- Testing
- Imaginal exposure
- Where
- 2 sites in Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Phobias Snakes, Phobias Spiders
Bringing Exposure Therapy to Real-Life Context With Augmented Reality
In this patented project, U.S. Patent No. 10,839,707, the investigators will develop an augmented reality exposure therapy method for arachnophobia, and fear of snakes, to test in the clinic.
- Trial name
- ARET (NCT03649347)
- Testing
- Augmented reality exposure therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wayne State University
Phobia, Specific
Influence of Valproic Acid on Extinction-based Therapy in Patients With Fear of Spiders.
The purpose of this study is to evaluate whether valproic acid in combination with fear memory reactivation is useful to enhance treatment stability of exposure therapy for specific phobia.
- Trial name
- VALPRO (NCT02789813)
- Testing
- Valproic Acid, Fear reactivation, No fear reactivation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Specific Phobia
Extinction Generalization in Exposure Therapy
Patients with anxiety disorders oftentimes express fear responses to more than only one fear-inducing object. The principal aim of this study is to examine whether the beneficial effects of exposure on fear reduction in spider…
- Trial name
- NCT03031002
- Testing
- Exposure treatment for spider fear
- Volunteers
- 77 people
- Sponsor
- Ruhr University of Bochum
Acrophobia, Arachnophobia
3D Video Virtual Reality Exposure Therapy Study
This study seeks to examine a Virtual Reality Exposure Therapy (VRET) using the 3D Video Virtual Reality (VR) technology for the fear of spiders.
- Trial name
- 3D-VVRET (NCT02584387)
- Testing
- 3D Video Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Arachnophobia, Cynophobia
Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs.
- Conditions
- Arachnophobia, Cynophobia, Ophidiophobia
- Trial name
- NCT06302868
- Testing
- Telemedicine Exposure Therapy Using Photos and Videos, Telemedicine-Based Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of South Florida
One Week Follow-up Assessment, Six Weeks Follow-up Assessment
The Effect of Time on Generalization of Exposure-based Benefit
Participants will receive a pre-assessment and an exposure with a control spider. This control spider will be presented again at post-training assessments.
- Conditions
- One Week Follow-up Assessment, Six Weeks Follow-up Assessment, Three Months Follow-up Assessment
- Trial name
- NCT06255821
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Ruhr University of Bochum
Phobic Disorders
Neurophysiological Correlates of Exposition Therapy in Spider Phobia
This study aims to investigate the neurophysiological correlates of spider phobia and its treatment with CBT based Exposure Therapy.
- Trial name
- NCT03653923
- Testing
- Exposure Therapy
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Spider Fear, Arachnophobia
Feasibility of an Online Modeled Exposure in Spider Fearful Individuals
The effectiveness of an optimized group exposure treatment is investigated in spider-fearful individuals. Participants will undergo an optimized standardized exposure treatment.
- Trial name
- OMEX (NCT06182709)
- Testing
- online psychoeducation video + modeled exposure, live psychoeducation video + modeled exposure, group exposure
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Philipps University Marburg
Anxiety Disorders, Arachnophobia
Optimizing Exposure Therapy With Mental Rehearsal
Treatment response rates for cognitive behavioral therapy (CBT) across anxiety disorders average approximately 50% post-treatment (Loerinc et al, 2015), evidencing significant 'return of fear', the re-emergence of a partially or…
- Trial name
- NCT03934385
- Testing
- Mental Rehearsal, Exposure
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles
Phobia, Specific
The Impact of Sex Hormones on One-session Treatment for Spider Phobia in Women
The purpose of this study is to determine whether levels of sex hormones (including estrogen and progesterone) influence women's response to treatment for Specific Phobia of spiders.
- Trial name
- NCT02622087
- Testing
- One-Session-Treatment
- Where
- Australia
- Volunteers
- 90 people
- Sponsor
- The University of New South Wales
Specific Phobia
The Effects of Safety Seeking Behaviors During Exposure Therapy for Adults With Spider Phobia
Exposure-based cognitive-behavioral therapy (i.e., "exposure therapy"), which entails repeated and prolonged confrontation with feared situations/stimuli, is the most effective treatment for anxiety disorders (e.g.…
- Trial name
- NCT03233113
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Fear of Spiders, Fear of Heights
Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure
This study investigates whether a one-session exposure treatment for spider-related stimuli can lead to a generalization of extinguished fear to height-related stimuli in individuals with comorbid fear of spiders and fear of…
- Trial name
- NCT03907345
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum