Clinical trials: Arterial Aneurysm
Vasodilation
Effects of Exercise Training on Vascular Endothelial Function of Patients Submitted to Coronary Artery Bypass Graft
Objective: To observe the effects of exercise training on vascular endothelial function in patients undergoing coronary artery bypass graft (CABG) alone in phase III after six months of Cardiac rehabilitation programs (CRP).
- Trial name
- NCT02265107
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Universidade Federal do Rio Grande (FURG)
Aorta Aneurysm, Carotid Arteriosclerosis
The Role Oral Microbiome in the Development and Progression of Aorta Aneurysm and Carotid Atherosclerosis
The goal of this observational study is to compare the microbiome (bacterial al community) of the diseased vascular site and the oral cavity with specific attention to chronic inflammatory periodontitis in patients who have aorta…
- Trial name
- OMB (NCT07824921)
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Semmelweis University
Coronary Artery Ectasia
Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients
The investigators thought to explore arrhythmias outcome - hidden arrhythmias, ECG features: Tp-Te interval and Tp-Te/QTc ratio, fQRS among patients with coronary artery ectasia as compared to normal coronary artery patients.
- Trial name
- NCT05106530
- Testing
- Holter, ECG
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abdominal Aortic Aneurysm
Relation betwEen Abdominal Aorta and Carotid Artery Responses to SymPathetic stimulatiON uSing duplEx Ultrasound
Abdominal aortic aneurysm (AAA) is a common vascular disease and associated with risk of rupture, but also with a high cardiovascular (CV) event rate. A key difficulty in AAA is predicting these life-threatening complications.
- Trial name
- RESPONSE (NCT04035252)
- Testing
- Carotid artery reactivity test (CAR-test)
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Aneurysm, Aneurysm, Brain
Setting Benchmarks for Microsurgical Clipping of Unruptured Intracranial Aneurysms
To conduct a retrospective multicenter cohort study to define benchmark values for best achievable outcomes following microsurgical clipping of unruptured intracranial aneurysms (UIA).
- Conditions
- Aneurysm, Aneurysm, Brain, Aneurysm Cerebral, Aneurysm of Cerebral Artery
- Trial name
- NCT05029947
- Testing
- Microsurgical Clipping of Unruptured Intracranial Aneurysm
- Where
- Germany
- Volunteers
- 3,000 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Intracranial Aneurysm
Neuroform Atlas Stent System Study
The primary objective of this study is to demonstrate effectiveness and safety of the Neuroform Atlas Stent System for use with bare metal embolic coils.
- Trial name
- ATLAS (NCT02340585)
- Testing
- Next Generation Neuroform Stent System
- Where
- 25 sites in United States
- Volunteers
- 298 people
- Sponsor
- Stryker Neurovascular
Vascular Surgical Procedure, Peripheral Arterial Disease(PAD)
Lymphatic Injury Visualization in Vascular Surgery
This study aims to assess a simple intervention: Visualization of lymphatic injury + treatment (in case of detection). This will generate data on the incidence of intraoperative lymphatic injury and the effect of treatment.
- Conditions
- Vascular Surgical Procedure, Peripheral Arterial Disease(PAD), Acute Ischemia, Hemmorhage
- Trial name
- LymphFistula-P (NCT07499206)
- Testing
- Visualization of lymphatic injury and treatment of injury (in case of detection)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiac Surgery, Coronary Artery Bypass Grafting
Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery
The purpose of the present research study is to investigate the pharmacokinetics, as well as safety, tolerability and pharmacodynamics of different ascending dosing regimens of AP214 in patients undergoing cardiac surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery, Aortic Root or Ascending Aortic Aneurysm Repair Surgery
- Trial name
- NCT00903604
- Testing
- AP214
- Where
- 2 sites in Denmark
- Volunteers
- 42 people
- Sponsor
- Action Pharma A/S
Intracranial Aneurysm
pCONus Treatment of Wide Neck Intracranial Aneurysms
To assess safety and efficacy of pCONus for the treatment of wide neck bifurcation aneurysms.
- Trial name
- pToWin (NCT02554708)
- Testing
- implantation of the pCONus Bifurcation Aneurysm Implant
- Where
- 10 sites in Argentina, Austria and 3 more
- Volunteers
- 116 people
- Sponsor
- Phenox GmbH
Intracranial Aneurysm, Arteriovenous Malformations, Cerebral
Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping
Endovascular procedures for treating brain aneurysms and arteriovenous malformations (AVMs) are becoming increasingly popular due to their less invasive nature and lower risk of complications.
- Trial name
- NCT06588543
- Testing
- Endovascular treatment
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- University Hospital, Ghent
Carotid Artery Aneurysm
Carotid Artery Aneurysm Treatment Using CGuard Divert-And-Heal Strategy
Non-randomized, single arm, open label, academic observational study of CGuard MicroNet covered stent system use to achieve endovascular lumen reconstruction in carotid artery aneurysms with indications for treatment (enlarging…
- Trial name
- C-HEAL (NCT04434456)
- Testing
- CGuard stent implantation
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- John Paul II Hospital, Krakow
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Intracranial Aneurysms
Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support)
The purpose of this study is to evaluate the safety and efficacy of the Low Profile Visualized Intraluminal Support(LVIS™ and LVIS™ Jr.)devices from MicroVention, Inc.
- Trial name
- LVIS (NCT01793792)
- Testing
- LVIS™ and LVIS™ Jr
- Where
- 21 sites in United States
- Volunteers
- 153 people
- Sponsor
- Microvention-Terumo, Inc.
Ruptured Cerebral Aneurysm, Subarachnoid Hemorrhage (SAH)
Barrow Ruptured Aneurysm Trial
With evolving endovascular technologies there is a growing debate centered on the relative safety and efficacy of the currently accepted alternatives for the treatment of ruptured cerebral aneurysms in the face of acute…
- Trial name
- BRAT (NCT01593267)
- Testing
- coil embolization, clip occlusion
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Middle Cerebral Artery Aneurysm
Prospective, Multicenter Cohort Study on the Safety and Efficacy of Treatment for Middle Cerebral Artery Aneurysms
Intracranial aneurysm is one of the most common cerebrovascular diseases, with a prevalence of about 3.2%. With the aging of the population and the further popularization of MRA and other examination methods, the prevalence of…
- Trial name
- NCT04927520
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intracranial Aneurysm, Aneurysm, Brain
Dimethyl Fumarate Treatment for Intracranial Unruptured Aneurysms.
This study was designed to identify whether there is a measurable reduction in inflammation in walls of intracranial aneurysms with oral dimethyl fumarate.
- Conditions
- Intracranial Aneurysm, Aneurysm, Brain, Inflammation Vascular
- Trial name
- NCT05959759
- Testing
- Dimethyl fumarate
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Aneurysm Cerebral (Unruptured)
Dual Antiplatelet Therapy Adherence With Reminder App Usage
The purpose of this study is to evaluate Dual Antiplatelet Therapy adherence in patients undergoing stent-based endovascular treatment for unruptured cervical and intradural, intracranial aneurysms.
- Trial name
- NCT05071027
- Testing
- Endovascular Neurosurgery
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Montefiore Medical Center
Intracranial Aneurysm
Low Dose Prasugrel vs Clopidogrel for Stenting or Flow Diverter for Unruptured Aneurysm
Low clopidogrel response has been reported in about 5-44% of the total population, which is associated with an increase in thromboembolism. Recently prasugrel drug widely accepted as a good option for these patients.
- Trial name
- NCT05359224
- Testing
- Prasugrel group, Clopidogrel group
- Where
- South Korea
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cerebral Aneurysm
Decision Aids in Cerebral Aneurysm Treatment
Identifying and making a decision about the best health treatment or screening option can be difficult for patients. Decision aids can be used when there is more than one reasonable option, when no option has a clear advantage in…
- Trial name
- NCT02503553
- Testing
- Option grid for cerebral aneurysm treatment, Control
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Aneurysm Cerebral
Interest of a Simulated Procedure Performed on a Printed Model in the Endovascular Treatment of Carotid-sylvian Aneurysms
It is now considered that 1% to 2% of the French population has an intracranial aneurysm. The major risk of this malformation is essentially the rupture which will lead in 10% of cases to death immediately, in 30% to 50% death…
- Trial name
- Anev3D (NCT05419661)
- Testing
- Operational Pre-Planning
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest