Clinical trials: Arterial Hypotension
Spine Surgery, Intraoperative Hypotension
Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS)
The purpose of this research is to compare two commonly used medications, phenylephrine and norepinephrine, that are used to treat low blood pressure during complex spine surgery.
- Conditions
- Spine Surgery, Intraoperative Hypotension, Tissue Perfusion
- Trial name
- NCT07796282
- Testing
- Phenylephrine hydrochloride infusion, Norepinephrine bitartrate infusion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Hypotension, Anesthesia
The Hypotensive Effect of Propofol: an Observational Study
Hypotension is a recognized frequent complication of induction of anesthesia. The intent of this research is to determine the incidence of hypotension in patients receiving anesthetic induction with propofol.
- Trial name
- NCT01508351
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Milton S. Hershey Medical Center
Hypotension During Surgery, Prevention of Hypotension
"Hypotension Probability Indicator" in TAVI/MitraClip for Hypotension Management
The study will investigate whether the use of Goal Directed Hemodynamic Therapy implemented with the HPI algorithm using a treatment algorithm will reduce the incidence of hypotension and improve treatment of hypotension.
- Trial name
- NCT06347211
- Testing
- Acumen IQ sensor with Hemosphere monitor incorporating the HPI algorithm
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Spinal Anaesthesia Induced Hypotension
Role of Ondansetron in Spinal Anaesthesia Induced Hypotension
The objective of this study is to determine the effect of ondansetron on the total consumption of norepinephrine infusion needed to prevent spinal anaesthesia induced hypotension in cesarean section.
- Trial name
- NCT06727201
- Testing
- Ondansetron (Zofran)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Perioperative/Postoperative Complications
Ability of Hypotension Prediction Index to Predict Hypotension Events in Thoracic Surgery
Investigators design this prospective observational study to exam the ability of hypotension prediction index in predicting intraoperative hypotension events in each phase of thoracic surgery
- Trial name
- NCT05117151
- Testing
- hypotension prediction index
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Anesthesia, Sedation
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful.
- Conditions
- Anesthesia, Sedation, Monitored Anesthesia Care, Procedure
- Trial name
- MACS (NCT07022951)
- Testing
- Preoperative fasting
- Where
- United States
- Volunteers
- 1,200,000 people
- Sponsor
- Massachusetts General Hospital
Hypotension
Can Passive Leg Raise Prevent Spinal Anesthesia-induced Hypotension During Cesarean Section?
All over the world, spinal anesthesia is widely used in cesarean sections due to its superiority over general anesthesia. Due to reasons such as increased sensitivity to local anesthetics and increased intra-abdominal pressure in…
- Trial name
- NCT04673253
- Testing
- Passive leg Raise, control
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Antalya Training and Research Hospital
Intradialytic Hypotension
Evaluation of the Impact of L- Carnitine in Intradialytic Hypotension in Pediatric Patients on Regular Hemodialysis
Intradialytic hypotension (IDH) is defined as less than the 5th percentile of SBP measurements and is associated with clinical symptoms, such as abdominal pain, nausea, vomiting, muscle cramps, restlessness, light-headedness…
- Trial name
- NCT05905692
- Testing
- L Carnitine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Blood Pressure
Clinical Evaluation of the Performance of Bionet Sphygmomanometer Modules Based on Protocol Presented by the International Organization for Standardization
According to INTERNATIONAL STANDARD (hereafter ISO) blood pressure (BP) monitor clinical evaluation protocol (ISO 81060-2:2018, Non-invasive sphygmomanometers- Part2: Clinical investigation of intermittent automated measurement…
- Trial name
- NCT06609486
- Testing
- Blood pressure measurement group
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hoon-Ki Park
Autoimmune Autonomic Ganglionopathy (AAG)
Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy
The purpose of the study is to see if administering intravenous immune globulin (IVIG) (putting immune globulin directly into your blood) helps to improve the symptoms of orthostatic hypotension (sudden fall in blood pressure…
- Trial name
- NCT01522235
- Testing
- Double blinded IVIg, Single Blinded IVIg
- Where
- 6 sites in United States
- Volunteers
- 6 people
- Sponsor
- Beth Israel Deaconess Medical Center
Post Operative Analgesia, Bradycardia
Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb Surgery
Severe pain associated with thigh and knee fractures makes the positioning for regional anesthesia a challenge. Different modalities to make patient pain free for spinal positioning, post op analgesia and patient satisfaction…
- Conditions
- Post Operative Analgesia, Bradycardia, Hypotension Drug-Induced
- Trial name
- 27G (NCT07221682)
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, USG GUIDED INFRA-INGUINAL FASCIA ILIACA BLOCK
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sahiwal medical college sahiwal
Cholangiopancreatography, Endoscopic Retrograde, Endoscopic Ultrasonography
Non-invasive Monitor in Endoscopic Invasive Procedure
Investigators include the patients who need painless invasive endoscopic procedure, investigators collect the demographic data and apply the non-invasive device ICON on participants during the who procedure.
- Trial name
- NCT03292627
- Testing
- Portable Noninvasive Hemodynamic Monitor
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Hypotension
Association Between Preoperative Shock Index and Hypotension After Spinal Anaesthesia for Non- Elective Caesarean Section
This is a prospective observational study done in parturient planned for non-elective caesarean section. Association between shock index (HR/SBP) and post-spinal hypotension in parturient undergoing non-elective caesarean section…
- Trial name
- NCT04692870
- Where
- Nepal
- Volunteers
- 337 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Hypotension
Norepinephrine in the Management of General Anesthesia-Induced Arterial Hypotension in Chronic Heart Failure Patients
Arterial hypotension is a frequent complication of general anesthesia and a significant contributor to postoperative complications.
- Trial name
- NORAFLOW (NCT06350929)
- Testing
- Cardiac output monitoring by the Starling™ SV Sebac®
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Hypotension
Focussed Echocardiography to Detect Preoperative Hypovolemia and Left Ventricular Dysfunction as a Predictor of Post-Induction Hypotension
This is an observational study to evaluate the role of a Bed side Focus assessed Transthoracic Echocardiography (FATE) in identifying the patients at a potential risk of developing hypotension secondary to general anesthesia…
- Trial name
- NCT02944266
- Testing
- Pre operative Focus assessed Transthoracic echocardiographic assessment.
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Hypertension, Post-Exercise Hypotension
Set Volume of Optimal Resistance Exercise to Generate Hypotension
This study evaluates the volume of optimal resistance exercise to generate postexercise hypotension after performing a single exercise in hypertensive elderly subjects.
- Conditions
- Hypertension, Post-Exercise Hypotension, Resistance Training
- Trial name
- NCT03957746
- Testing
- Resistance training
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- University of Valencia
Post-induction Hypotension (PIH), Hypertension (HTN)
Hemodynamic Effects of Lithotomy Position in Surgical Patients (PH-LITHO)
Anesthesia-induced hypotension is a common occurrence in elderly hypertensive patients and is closely associated with increased postoperative morbidity This study aims to investigate whether the lithotomy position, a…
- Conditions
- Post-induction Hypotension (PIH), Hypertension (HTN), Geriatric Anesthesia
- Trial name
- PIH-LITHO (NCT07549152)
- Testing
- Pre-induction Lithotomy Position, Standard Supine Position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trabzon Karadeniz Teknik Universitesi
Anesthesia, Hypotension
Anesthetic Advantages of Dexmedetomidine for Hypotensive Anesthesia
The aim of this study was to evaluate the positive anesthetic properties such as reduce intraoperative analgesic requirement, time to extubation and recovery, and early postoperative pain of dexmedetomidine used as a hypotensive…
- Trial name
- NCT02083055
- Testing
- Dexmedetomidine, Nitroglycerin
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy
Association of Preoperative Sarcopenia and Intraoperative Hypotension in Patients Undergoing Minimally Invasive Pylorus Preserving Pancreaticoduodenectomy : Prospective Observational Study
The aim of this study is to determine whether preoperative sarcopenia (low muscle strength/muscle mass) is correlated with time weighted average intraoperative hypotension in patients undergoing minimally invasive pylorus…
- Trial name
- NCT05320978
- Testing
- Hand grip test, computed tomography
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Yonsei University
Orthostatic Hypotension, Diabetes Mellitus Type 2
Orthostatic Hypotension and Diabetes Mellitus
Rationale: Orthostatic hypotension increases with age and is associated with increased vascular and all-cause mortality. The prevalence of orthostatic hypotension is also increased in diabetic subjects.
- Trial name
- ODET (NCT00807976)
- Where
- Netherlands
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical Research Foundation, The Netherlands
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