Clinical trials: Arterial Hypotension
Burns
Cardiac Output Monitoring in Burn Patients
The purpose of this study is to describe the use of non-invasive cardiac output monitors (NICOM) in patients with burn injuries and to develop a protocol for NICOM in a burn unit.
- Trial name
- NCT02404597
- Testing
- NICOM (non-invasive cardiac output monitor)
- Where
- United States
- Sponsor
- Emory University
Acute Kidney Injury, Hypotension
Is Permissive Hypotension Truly Harmless? Early Biomarker Evidence of Subclinical Kidney Injury in Rhinologic Surgery
This study aims to investigate the effects of permissive hypotension, which is routinely used in rhinologic surgeries such as rhinoplasty, septoplasty, and functional endoscopic sinus surgery (FESS), on renal function.
- Trial name
- NCT07328620
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multiple System Atrophy
Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA
Evaluate the effects of L-Threo DOPS on orthostatic hypotension symptoms and other non-motor symptoms in patients with Multiple System Atrophy (MSA) after 12 weeks following randomization to continued therapy with droxidopa or…
- Trial name
- DOPS-AMS (NCT02071459)
- Testing
- L-Threo DOPS
- Where
- 13 sites in France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Toulouse
Biliary Tract Diseases, Procedural Sedation and Analgesia
Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP
This study compares two anesthesia medications, esketamine and sufentanil, used together with propofol during ERCP procedures. The goal is to find out which combination provides better safety and comfort for people undergoing…
- Trial name
- ES-ERCP (NCT07702240)
- Testing
- Esketamine, Sufentanil
- Volunteers
- 530 people
- Sponsor
- Ren Da
Hypotension, Anesthesia-Induced Hypotension
Arterial Stiffness and Hemodynamics in Cardiac Surgery
Background: Hypotension during the induction of anesthesia is a significant clinical condition associated with increased perioperative morbidity and mortality.
- Conditions
- Hypotension, Anesthesia-Induced Hypotension, Arterial Stiffness, Cardiovascular Diseases
- Trial name
- NCT06911593
- Testing
- Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Konya City Hospital
Hypotension Symptomatic, Parkinson's Disease
Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease
The PD-HemON study aims to evaluate the safety and preliminary efficacy of ARC-IM Therapy (Epidural Electrical Stimulation) to support hemodynamic management in people with typical and atypical Parkinson's Disease, who suffer…
- Conditions
- Hypotension Symptomatic, Parkinson's Disease, Orthostatic Hypotension, Dysautonomic, Multiple System Atrophy (MSA) With Orthostatic Hypotension
- Trial name
- PD-HemON (NCT06920134)
- Testing
- ARC-IM Investigational System
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
The Ability Of Inferior Vena Caval Distensibility Index With Passive Leg Raising Test To Predict Spinal Anesthesia-induced Hypotension In Elderly Patients Undergoing Infra-umbilical Surgeries. A Prospective Observational Study.
Many previous studies have investigated the ability of various methods such as passive leg raising test , and inferior vena cava collapsibility index in predicting post-spinal hypotension, but none of them have succeeded in…
- Trial name
- NCT05991063
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Spinal Anesthesia Hypotension
Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial
Neuraxial blockade such as spinal anaesthesia can cause severe hypotension due to pharmacological sympathectomy resulting in potential deleterious consequences for the patient, Prevention of this spinal anaesthesia induced…
- Trial name
- NCT06213935
- Testing
- Norepinephrine, Midodrine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Anesthesia, Hypotension on Induction
Intraoperative Hypotension in High-risk Patients Undergoing Surgery
The primary objective of this observational study is to investigate the risk factors for intraoperative hypotension and identify the underlying pathomechanisms leading to it, both during the period after general anesthesia…
- Conditions
- Anesthesia, Hypotension on Induction, Perioperative Injury, Perioperative Hypotension
- Trial name
- IRIoHYP (NCT05884918)
- Where
- Poland
- Volunteers
- 2,000 people
- Sponsor
- Mazovia Regional Hospital in Siedlce
Chronic Kidney Disease, Hypertension
Aerobic Training and Arterial Stiffness in Chronic Kidney Disease (CKD) Patients
The current study is designed to examine the impact of 16 weeks of moderate intensity aerobic training on arterial stiffness and blood pressure in stage 3 chronic kidney disease (CKD) patients.
- Conditions
- Chronic Kidney Disease, Hypertension, Diabetes
- Trial name
- NCT01399489
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Springfield College
Intraoperative Hypotension
Effects of Sufentanil on the Intraoperative Hemodynamics
This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.
- Trial name
- NCT06091904
- Testing
- Sufentanil, Remifentanil
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Cardiac Surgery, Intraoperative Hemodynamic Instability
Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery
Intraoperative hemodynamic instability (IOHI) is a common occurrence during cardiac surgery and is associated with organ hypoperfusion. However, the specific impact of IOHI on composite adverse outcomes remains unclear.
- Conditions
- Cardiac Surgery, Intraoperative Hemodynamic Instability, Postoperative Complication, Acute Kidney Injury
- Trial name
- NCT07324694
- Where
- Turkey (Türkiye)
- Volunteers
- 351 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Symptomatic Neurogenic Orthostatic Hypotension, MSA - Multiple System Atrophy
Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy
This is a Phase 3, multi-center, randomized withdrawal study to evaluate the efficacy and durability of ampreloxetine in participants with MSA and symptomatic nOH after 20 weeks of treatment.
- Trial name
- CYPRESS (NCT05696717)
- Testing
- Ampreloxetine
- Where
- 79 sites in United States, Argentina and 18 more
- Volunteers
- 102 people
- Sponsor
- Theravance Biopharma
Hypotension
ET 50 for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50 (NCT01561274)
- Testing
- 2 ml bupivacaine, 1.5 ml bupivicaine.
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chest Pain, Dyspnea
Impact of Immediate Point-of-Care Ultrasound on Patients With Cardiopulmonary Symptoms in the Emergency Department
The purpose of the proposed research is to examine whether incorporating point-of-care ultrasound (POCUS) early in diagnostic work-up of cardiopulmonary complaints will affect diagnosis, time to condition-specific intervention…
- Conditions
- Chest Pain, Dyspnea, Syncope, Hypotension
- Trial name
- NCT02861508
- Testing
- Point-of-care ultrasound, Usual care
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Yale University
Post-spinal Hypotension, Cesarean Section
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension During Caesarean Section
Maternal hypotension after spinal block is a common complication after subarachnoid block in this population. The incidence of maternal hypotension is nearly 60% when prophylactic vasopressors are not used.
- Trial name
- NCT05051150
- Testing
- Epinephrin 0.03, Epinephrin 0.05, Epinephrin 0.07
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Kasr El Aini Hospital
Orthostatic Hypotension, Postural Hypotension
Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury
Individuals with acute cervical spinal cord injury (SCI) can suffer from an excessive and prolonged fall in blood pressure when assuming an upright position, such as transitioning from lying to sitting or standing, a condition…
- Trial name
- NCT01874782
- Testing
- transcranial electrical stimulation
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of British Columbia
E03.155.253, Bispectral Index Monitor
The Use of Sedation Score and Bispectral Index for Induction in Geriatric Patients
The main objective of this clinical study is to determine the effectiveness of BIS-guided propofol administration in avoiding hypotension during propofol induction in geriatric patients.
- Conditions
- E03.155.253, Bispectral Index Monitor, Hypotension
- Trial name
- NCT06232980
- Testing
- urological surgical intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Ankara City Hospital Bilkent
Cesarean Section Complications, Anesthesia Complication
Prophylactic Phenylephrine Co-administration During Caesarean Section
This single centre prospective alternating intervention study will aim to compare prophylactic phenylephrine given in the first litre of Ringers lactate as co-load in healthy patients having an elective caesarean section under…
- Trial name
- NCT04005664
- Testing
- Phenylephrine
- Where
- South Africa
- Volunteers
- 300 people
- Sponsor
- University of KwaZulu
Hypotension
Study the Effect of Electroacupuncture on Prevention and Treatment of Hypotension After Intraspinal Anesthesia
The purpose of this study is to assess the prevention and treatment effect of transcutaneous acupoint electrical stimulation on hypotension after intraspinal anesthesia.
- Trial name
- NCT05163990
- Testing
- transcutaneous acupoint electrical stimulation
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.