Clinical trials: Arterial Hypotension
Postspinal Hypotension, Cesarean Delivery
Two Norepinephrine Rescue Bolus Doses for Management of Severe Post-spinal Hypotension During Elective Cesarean Delivery
Maternal hypotension after spinal block is a common complication after subarachnoid block in this population whose incidence reached 60% in many reports.
- Conditions
- Postspinal Hypotension, Cesarean Delivery, Norepinephrine
- Trial name
- NCT05290740
- Testing
- Norepinephrine 5 mcg, Norepinephrine 10 mcg
- Where
- Egypt
- Volunteers
- 158 people
- Sponsor
- Kasr El Aini Hospital
General Anesthesia, Hypotension on Induction
Ultrasonographic Predictors of Hypotension After Induction
The purpose of the study is to evaluate the predictive value of the inferior vena cava collapsibility index and caval aorta index for detecting hypotension after induction of general anesthesia.
- Trial name
- NCT05239234
- Testing
- Inferior vena cava-Aorta diameter index
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Antalya Training and Research Hospital
Breast Tumors, Hypotension
Levobupivacaine and Lidocaine for Paravertebral Block Causes Greater Hemodynamic Oscillations Than Levobupivacaine
The purpose and the goal of this paper is to show whether the application of a combination of two local anesthetics, as opposed to the application of one local anesthetic at paravertebral block changes the hemodynamic variable.
- Conditions
- Breast Tumors, Hypotension, Bradycardia
- Trial name
- NCT02004834
- Testing
- levobupivacaine
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Airway Management, Tracheal Intubation
Taiwan ED Airway Quality Surveillance Registry (TEAR)
This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan.
- Conditions
- Airway Management, Tracheal Intubation, Emergency Department, Peri-intubation Adverse Events
- Trial name
- NCT07574450
- Where
- Taiwan
- Volunteers
- 1,200 people
- Sponsor
- Chang Gung Memorial Hospital
Pregnancy, Cesarean Delivery
Crystalloid Versus Colloid Rapid Co-load for Cesarean Delivery Under Spinal Anesthesia
The study aims to compare crystalloid co-loading and colloid co-loading in parturients receiving prophylactic phenylephrine infusion during cesarean delivery in terms of the incidence of hypotension.
- Conditions
- Pregnancy, Cesarean Delivery, Hypotension
- Trial name
- NCT03729076
- Testing
- Crystalloid, Colloid
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Complication of Anaesthesia During Labour and Delivery
Plethysmographic Variability Index in Post Spinal Anesthesia Hypotension in Cesarean Section
Full term pregnant female patients presented for elective C.S for single viable fetus will be included in this study. Before anesthesia, the patient will be attached to a monitor of: ECG , heart rate, non invasive blood pressure…
- Trial name
- NCT04010318
- Testing
- Spinal Anesthesia
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Hypotension, Anesthesia
Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Patient undergoing general anesthesia in elective surgery will be assigned to receive either methohexital or propofol general anesthesia.
- Trial name
- NCT02624050
- Testing
- Methohexital, Propofol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autonomic Failure, Orthostatic Hypotension
Treatment of Orthostatic Hypotension in Autonomic Failure
The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function.
- Trial name
- NCT00223691
- Testing
- Atomoxetine, Acarbose, Pyridostigmine Bromide
- Where
- United States
- Volunteers
- 389 people
- Sponsor
- Vanderbilt University
Cardiac Surgery
Controling Mean Arterial Pressure Using a Closed-Loop System for Vasopressor Titration
The investigators have developed an automated vasopressor controller to improve the titration of vasopressor in order to maintain mean arterial pressure (MAP) within a narrow range and have recently shown the controller was…
- Trial name
- COMAP (NCT04586218)
- Testing
- Computer guided vasopressor infusion, Manual control of vasopressor infusion
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Clinique de la Sauvegarde
End Stage Renal Disease, Hypotension During Dialysis
Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices
Open label, randomized, cross-over clinical study comparing the acute effect of high versus low protein meals during dialysis on intradialytic blood pressure, 24-hour ambulatory blood pressure and arterial stiffness indices on…
- Conditions
- End Stage Renal Disease, Hypotension During Dialysis, Protein Malnutrition, Arterial Sclerosis
- Trial name
- NCT03947710
- Testing
- High-protein meals, Low- protein meals, No meals
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aristotle University Of Thessaloniki
Parkinsonism
The Effect of Spinal Cord Stimulation on Orthostatic Hypotension in Parkinsonism and Its Related Mechanisms
Parkinson's disease (PDS) is a syndrome characterized by tremor, bradykinesia, rigidity, and postural disturbances. Causes include Parkinson's disease (PD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and…
- Trial name
- NCT07322458
- Testing
- Epidural spinal cord stimulation, Transcutaneous spinal cord stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ruijin Hospital
Hip Fractures, Anesthesia
Fractional Spinal Anesthesia and Systemic Hemodynamics in Frail Elderly Hip Fracture Patients.
Aging and frailty make the elderly patients susceptible to hypotension following spinal anaesthesia. The systemic haemodynamic effects of spinal anaesthesia are not well known.
- Conditions
- Hip Fractures, Anesthesia, Hypotension Drug-Induced, Cardiac Output, Low
- Trial name
- NCT05101291
- Testing
- Bupivacain
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Sahlgrenska University Hospital
Neurogenic Orthostatic Hypotension
A Study in Subjects With Neurogenic Orthostatic Hypotension
This is a study to evaluate the effects of CST-3056 on orthostatic symptoms and signs in subjects with neurogenic orthostatic hypotension (nOH).
- Trial name
- NCT07089043
- Testing
- CST-3056
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- CuraSen Therapeutics, Inc.
Hypertension, Hypotension
Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure
The purpose of this study is to determine whether continuing or discontinuing furosemide (a diuretic) on the day of elective noncardiac surgery for those who take furosemide on a chronic basis, causes more intraoperative…
- Conditions
- Hypertension, Hypotension, Edema, Congestive Heart Failure
- Trial name
- NCT00115726
- Testing
- furosemide
- Where
- 3 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- University of Calgary
Monitoring During Deliberate Hypotensive Anesthesia
Peripheral Perfusion Index (PPI) as Monitor During Deliberate Hypotensive Anesthesia
Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue.
- Trial name
- PPI (NCT03007355)
- Testing
- peripheral perfusion index measurement
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cirrhosis, End Stage Liver Disease
Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis
Ascites is a frequent complication of patients with portal hypertension. As portal hypertension progresses, a percentage of these patients develop refractory ascites.
- Conditions
- Cirrhosis, End Stage Liver Disease, Ascites, Hypotension
- Trial name
- NCT01331785
- Testing
- Midodrine
- Where
- United States
- Sponsor
- The Cleveland Clinic
Hypotension in Pregnant Women, Headache in Pregnant Women
Prediction of Hypotension and Postdural Puncture Headache by Carotid Artery Corrected Flow Time
Anesthesia for cesarean delivery can be provided through general or neuraxial anesthesia (spinal or epidural). Hypotension is a common complication of both methods.
- Trial name
- NCT07372313
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Hypotension
The Effects of Plantar Stimulation on Hypotension, Treatment Efficacy and Quality of Life With Adults on Hemodialysis
For the end stage renal disease (ESRD) patients undergoing hemodialysis treatment, specifically, reflex mediated calf muscle pump stimulation has the potential to significantly reduce the number and magnitude of hypotensive…
- Trial name
- NCT00822653
- Testing
- Calf Muscle Pump Stimulation
- Sponsor
- Binghamton University
Spinal Cord Injuries, Spinal Cord Diseases
Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)
The goal of this clinical trial is to evaluate the effect of transcutaneous spinal cord stimulation on blood pressure in individuals with an acute spinal cord injury (within 30 days of injury).
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Trauma, Nervous System, Nervous System Diseases
- Trial name
- SCI (NCT05731986)
- Testing
- Orthostatic challenge, Biostim-5 transcutaneous spinal stimulation - Mapping, Biostim-5 transcutaneous spinal stimulation - "Optimal" testing
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
Acute Kidney Injury, Acute Kidney Disease
The Effect of Preoperative Biological Age on Hemodynamics and Renal Function
Background The aim of this study is to explore the potential value of preoperative biological age as a predictor of intraoperative hemodynamic changes and postoperative renal function injury.
- Conditions
- Acute Kidney Injury, Acute Kidney Disease, Intraoperative Hypotension, Post-induction Hypotension
- Trial name
- NCT07080086
- Volunteers
- 268,833 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
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