Clinical trials: Arterial Ischemic Stroke
Stroke Not Otherwise Specified, Control Condition
Vessel Angles and Diameters in Stroke Disease
Retrospective analysis of internal carotid artery morphology on CT angiography images of patients with acute ischemic stroke.
- Trial name
- NCT06756724
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Atherosclerosis, Ischemia
Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737)
The study is designed to determine whether vorapaxar, when added to the existing standard of care (SOC) for preventing heart attack and stroke (eg, aspirin, clopidogrel) in participants with a known history of atherosclerosis…
- Conditions
- Atherosclerosis, Ischemia, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- NCT00526474
- Testing
- Vorapaxar
- Volunteers
- 26,449 people
- Sponsor
- Merck Sharp & Dohme LLC
Stroke, Ischemic
Neuroprotective Effect of Remote Ischemic Conditioning in Ischemic Stroke Treated With Mechanical Thrombectomy
The benefit of mechanical thrombectomy in the treatment of ischemic stroke has been demonstrated in several multicenter randomized trials.
- Trial name
- PROTECT-I (NCT03915782)
- Testing
- Remote ischemic conditioning
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Hospices Civils de Lyon
Major Cardiovascular Event, Established Atherosclerotic Cardiovascular Disease
A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular Disease
The primary objective of the study is to evaluate real-world effectiveness of treatment with Repatha® in combination with SOC, compared with SOC alone, on the risk for cardiovascular (CV) death, myocardial infarction (MI)…
- Trial name
- NCT06295679
- Where
- 90 sites in China
- Volunteers
- 7,000 people
- Sponsor
- Amgen
Brain Ischemia, Stroke, Ischemic
Effectiveness of a Neuromuscular Exercise Program and Visual Feedback in the Management of Body Position for Stroke Survivors
The aim of the biomedical research is to evaluate the changes of body position management during standing and walking for stroke patients, using innovative training methods during the rehabilitation.
- Trial name
- NCT05187559
- Testing
- Standard physiotherapy, Biodex Balance SD and Biodex Gait Trainer
- Where
- Lithuania
- Volunteers
- 120 people
- Sponsor
- Lithuanian University of Health Sciences
Acute Ischemic Stroke
Safety and Tolerability of Adjunctive TBO-309 in Reperfusion for Stroke
STARS is a prospective, multicentre, open-label, dose escalation, Phase IIa study to assess the safety and tolerability of TBO-309, an adjuvant antiplatelet therapy, in patients with AIS.
- Trial name
- STARS (NCT05363397)
- Testing
- TBO-309
- Where
- 7 sites in Australia
- Volunteers
- 80 people
- Sponsor
- The Florey Institute of Neuroscience and Mental Health
Tachyarrhythmia, Atrial Fibrillation (AF)
Master Study of the BIOMONITOR III and Incision and Insertion Tool (FIT OneStep)
This study is a post-market clinical follow-up (PMCF) study to identify and evaluate residual risks associated with the use of the BIOMONITOR III and BIOMONITOR IIIm that are discovered or remain even after risk analysis, risk…
- Conditions
- Tachyarrhythmia, Atrial Fibrillation (AF), Syncope, Cryptogenic Stroke
- Trial name
- NCT04025710
- Testing
- BIOMONITOR III and BIOMONITOR IIIm
- Where
- 27 sites in Australia, Austria and 4 more
- Volunteers
- 167 people
- Sponsor
- Biotronik SE & Co. KG
Stroke
The Role of Peripheral Afferents in Modulating Post-stroke Central Pain
Central post-stroke pain (CPP) is extremely difficult to relieve and responds very poorly to analgesics targeting neuropathic pain, probably because the mechanisms underlying this pain remain poorly understood.
- Trial name
- APEDOC (NCT06446960)
- Testing
- Lidocaine 20mg/ml, Levobupivacaine Hydrochloride 1.25 MG/ML, Sodium Chloride 0.9% Inj
- Where
- 2 sites in France
- Volunteers
- 33 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke, Ischemic, Strokes Thrombotic
Registry-based Stroke in Tunisia
Study the prevalence of strokes in the emergency department (ED) and their possible eligibility for thrombolysis.
- Conditions
- Stroke, Ischemic, Strokes Thrombotic, Stroke
- Trial name
- RAV-TUN (NCT05325606)
- Where
- Tunisia
- Volunteers
- 800 people
- Sponsor
- University of Monastir
Dyslipidemia, Coronary Heart Disease
Comparative Efficacy Evaluation of Lipids When Treated With Niaspan & Statin or Other Lipid-Modifying Therapies-COMPELL
The purpose of this study is to evaluate the effectiveness of first-line treatment using Niaspan (an extended release version of niacin) and statins versus other drugs that lower lipid levels, in subjects with elevated fat levels…
- Conditions
- Dyslipidemia, Coronary Heart Disease, Atherosclerosis, Stroke
- Trial name
- NCT00079638
- Testing
- Niacin, Atorvastatin, Simvastatin
- Volunteers
- 300 people
- Sponsor
- Kos Pharmaceuticals
Post-Stroke Cognitive Impairment (PSCI), Ischemic Stroke
Evaluation of Clinical Efficacy and Mechanism of Hand Jing-Well Acupoint Transcutaneous Electrical Stimulation in Improving Post-Stroke Cognitive Impairment
This study evaluates a non-invasive electrical stimulation therapy applied to specific acupoints on the fingers (called Jing-Well points) to improve thinking and memory problems after stroke.
- Conditions
- Post-Stroke Cognitive Impairment (PSCI), Ischemic Stroke, Cognitive Dysfunction, Cognitive Disorder, Hemorrhagic Strokes
- Trial name
- NCT07736885
- Testing
- Transcutaneous Electrical Stimulation at Jing-Well Acupoints
- Where
- China
- Volunteers
- 70 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Ischemic Stroke
Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry
To determine the revascularization rate, clinical efficacy and safety of the CE-marked MindFrame System in ischemic stroke patients
- Trial name
- PRIISM2 (NCT01560247)
- Testing
- Mechanical thrombectomy
- Volunteers
- 1,000 people
- Sponsor
- MindFrame, Inc.
Ischemic Stroke
Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN)
This is a double-blind parallel arm randomized trial aimed to assess efficacy and safety of intravenous Tenecteplase compared to intravenous Alteplase in eligible patients who present with symptoms of acute ischemic stroke within…
- Trial name
- TALISMAN (NCT02180204)
- Testing
- Tenecteplase, Alteplase
- Where
- United States
- Sponsor
- Reza Behrouz, DO
Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Acute Coronary Syndromes (ACS)
Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary Syndrome
Cardiovascular diseases are the leading cause of death worldwide. Among them, coronary artery disease-especially in its acute form, known as acute coronary syndrome (ACS)-is the most frequent cause of cardiovascular death.
- Conditions
- Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Acute Coronary Syndromes (ACS), Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease
- Trial name
- SurvSCA (NCT07112547)
- Where
- 10 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Blood Pressure, Ischemic Stroke
Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol
Confirm central blood pressure reduction effect of Fimasartan, Valsartan and Atenolol and compare correlation with the measured peripheral (central blood pressure, pulse wave velocity, and flow-mediated dilation) and cerebral…
- Trial name
- FAVOR (NCT02403349)
- Testing
- Fimasartan, Valsartan, Atenolol
- Volunteers
- 105 people
- Sponsor
- Ajou University School of Medicine
Ischemic Stroke
Stroke Adverse Outcome is Associated With Nosocomial Infections: PCTus- Guided Antibacterial Therapy in Severe Ischemic Stroke Patients (STRAWINSKI)
Development of stroke associated pneumonia (SAP) has a detrimental effect on stroke outcome. Biomarker-guided antibiotic treatment of patients at high risk for pneumonia may help to improve stroke outcome.
- Trial name
- STRAWINSKI (NCT01264549)
- Testing
- Procalcitonin assay - B.R.A.H.M.S PCT ultrasensitive Kryptor
- Where
- 6 sites in Germany, Spain
- Volunteers
- 230 people
- Sponsor
- Charite University, Berlin, Germany
Acute Ischemic Stroke, Large Vessel Occlusion
Study on the Efficacy and Safety of T-02 for the Treatment for Acute Ischemic Stroke
To examine the revascularization efficacy and safety of T-02 and its associated performance characteristics in treatment of appropriately selected subjects experiencing an acute ischemic stroke when the treatment is initiated…
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Vascular Occlusion, Thrombosis
- Trial name
- T-02 (NCT05342038)
- Testing
- T-02
- Sponsor
- Biomedical Solutions Inc.
Acute Ischemic Stroke
Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2
This study is a randomized, double-blind, placebo-controlled clinical trial. Investigators aim to assess the efficacy and safety of interleukin-6 receptor inhibitor combined with endovascular treatment in patients with acute…
- Trial name
- IRIS-2 (NCT07263776)
- Testing
- Tocilizumab
- Where
- 54 sites in China
- Volunteers
- 692 people
- Sponsor
- Capital Medical University
Upper Limb Ischemia, Stroke
Identification of Non-motor Brain Areas Involved in Upper Limb Motor Recovery After Stroke
Why: Upper-limb recovery post-stroke is challenging. Rehabilitation, aiming to induce plasticity takes an important place in patients' treatment.
- Trial name
- NOMO-Stroke (NCT05313776)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Ischemia Stroke, Post-stroke Depression
Nursing Health Education to Improve Functionality and Quality of Life After Ischemic Stroke
This study is titled "Effect of a Nursing Intervention Based on Health Education on Functionality, Depression Symptoms, and Quality of Life in Patients with Ischemic Stroke." It is a quasi-experimental, longitudinal, prospective…
- Conditions
- Ischemia Stroke, Post-stroke Depression, Post-stroke, Quality of Life
- Trial name
- NCT07343284
- Testing
- Health education Program
- Volunteers
- 70 people
- Sponsor
- University of Santiago de Compostela
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