Clinical trials: Arterial Occlusive Diseases
Coronary Artery Disease (CAD), Ischemic Heart Disease
Essential Pro PMCF Study ( rEPIC04E )
Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Essential Pro to meet EU Medical Device regulation (MDR) requirements in all the…
- Trial name
- rEPIC04E (NCT05292092)
- Testing
- Essential pro
- Where
- 7 sites in Spain
- Volunteers
- 161 people
- Sponsor
- Fundación EPIC
Peripheral Arterial Disease
ILLUMENATE Below-The-Knee (BTK) Arteries: a Post Market Clinical Study
The objective of this prospective, multi-center, single arm study is to obtain further data on the safety and performance of the StellarexTM 0.014" OTW Drug-coated Angioplasty Balloon in the treatment of lesions in "below the…
- Trial name
- BTK PMS (NCT03395236)
- Testing
- StellarexTM 0.014" Over-The-Wire Drug-coated Angioplasty Balloon
- Where
- 10 sites in Germany, Netherlands and 1 more
- Volunteers
- 49 people
- Sponsor
- Spectranetics Corporation
Revascularization, Carotid Artery Stenosis
Study on the Trans-Carotid Artery Occlusion Shunt System
The objective of the study is to evaluate the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System for Carotid Artery Revascularization during Endovascular Treatment
- Conditions
- Revascularization, Carotid Artery Stenosis, Carotid Artery Diseases
- Trial name
- NCT06924593
- Testing
- Trans-Carotid Artery Occlusion Shunt System
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Shenzhen Wecan Medical Technology Co.,Ltd
Coronary Artery Disease
Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia
Binodenoson (an experimental drug) and adenosine (an FDA-approved drug that is currently used by doctors) are used to increase blood flow to the heart just like when a person exercises on a treadmill.
- Trial name
- VISION-302 (NCT00944294)
- Testing
- binodenoson, adenosine
- Volunteers
- 419 people
- Sponsor
- Pfizer
Peripheral Arterial Disease
Augmentation of Limb Perfusion With Contrast Ultrasound
Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion.
- Trial name
- NCT03195556
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Intermittent Claudication, Peripheral Vascular Disease
Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication
The purpose of this study is to evaluate if Niacin ER/Lovastatin, at two different doses, compared to diet control (this group will receive a tablet containing 50 mg.
- Trial name
- NCT00062556
- Testing
- Niacin Extended Release and Lovastatin Tablets
- Volunteers
- 366 people
- Sponsor
- Kos Pharmaceuticals
HIV, Atherosclerosis
Effectiveness of Gut Microbiota-targeted Diatery Intervention Among People Living With HIV
The goal of this clinical trial is to conduct a dietary intervention targeting HIV specific gut microbiota alterations for primary atherosclerotic cardiovascular disease (ASCVD) prevention and evaluate its effectiveness in…
- Conditions
- HIV, Atherosclerosis, Diet, Healthy
- Trial name
- NCT06498401
- Testing
- gut microbiota-targeted dietary intervention
- Volunteers
- 110 people
- Sponsor
- Fudan University
Healthy Adult, Healthy
PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study)
The goal of this clinical trial is to determine the biodistribution, safety, and calculate the radiation dosimetry of the novel atherosclerotic PET imaging radiotracer, 64Cu-NODAGA-CANF, in normal healthy adult volunteers.
- Trial name
- NCT07800481
- Testing
- 64Cu-NODAGA-CANF
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cardiovascular Diseases, Coronary Arteriosclerosis
Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)
To determine if supplements of vitamin C, vitamin E, beta-carotene, and B-vitamins (a combination of folic acid, vitamins B6 and B12) reduce risk of major cardiovascular events in high risk women with a prior history of…
- Conditions
- Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease, Heart Diseases
- Trial name
- WAFACS (NCT00000541)
- Testing
- dietary supplements, vitamin C, vitamin E
- Sponsor
- Brigham and Women's Hospital
Atherosclerosis, Coronary, Diabetes Mellitus
Fat Around Heart Arteries as a Measure of Inflammation in Patients With Diabetes
In this prospective study, the objective is to investigate inflammation in the arteries of the heart. A heart CT scan (CCTA) will be used to measure inflammation by assessing the fat tissue surrounding the arteries of the heart.
- Conditions
- Atherosclerosis, Coronary, Diabetes Mellitus, Diabetes Mellitus Type 2, Inflammation
- Trial name
- PCAT-DM (NCT06644651)
- Where
- Denmark
- Volunteers
- 314 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease
Evaluation of the Accuracy, Safety and Robustness of a Single-input-single-output (SISO) Model-based Predictive Closed-loop System to Guide Patient-individualized ICU Sedation
The aim of this study is to investigate the accuracy, safety and robustness of a single-input-single output (SISO) model-based predictive closed-loop system to guide patient-individualized ICU sedation.
- Trial name
- NCT00735631
- Testing
- SISO model-based predictive closed-loop system
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- University Hospital, Ghent
Atherosclerosis, Cardiovascular Disease
A Study Investigating Blood Concentrations Of Rosuvastatin When Co-administered With GW856553 In Healthy Men
This study is being conducted to provide initial safety and tolerability data as well as to provide PK data on potential interactions when GW856553 and rosuvastatin are co-administered in healthy male adults
- Trial name
- NCT00549653
- Testing
- GW856553
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Total Occlusion of Coronary Artery
Drug-Coated Balloon Coronary Angioplasty Versus Stenting for Treatment of Disease Adjacent to a Chronic Total Occlusion.
This is an investigator-initiated, randomized, multi-center, non-inferiority clinical trial. Patients with a Chronic Total Occlusion who are eligible for PCI will be randomized to additional Drug-Coated-Balloon treatment or…
- Trial name
- Co-CTO (NCT04881812)
- Testing
- Drug-Coated Balloons, Drug-Eluting-Stent
- Where
- 2 sites in Netherlands
- Volunteers
- 144 people
- Sponsor
- Amsterdam UMC, location VUmc
Coronary Arteriosclerosis
This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.
This study was designed to assess the effects on coronary artery plaque using aggressive lipid-lowering therapy versus moderate lipid-lowering therapy.
- Trial name
- NCT00380939
- Testing
- Atorvastatin, Pravastatin
- Where
- 36 sites in United States
- Volunteers
- 600 people
- Sponsor
- Pfizer
Acute Ischemic Stroke, Basilar Artery Occlusion
Basilar Artery Occlusion Chinese Endovascular Trial in the Extended Time Window
A prospective, multi-center, randomized, controlled, open-label, blinded-endpoint trial to evaluate the safety and efficacy of endovascular mechanical thrombectomy for acute basilar artery occlusion in the extended time window
- Trial name
- BAOCHE2 (NCT06560203)
- Testing
- Mechanical thrombectomy
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Capital Medical University
Atherosclerosis
Vascular Effects of Ezetimibe/Simvastatin and Simvastatin on Atherosclerosis
Multiple clinical trials, using 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors (statins), have shown benefit in the primary and secondary prevention of atherosclerotic complications.
- Trial name
- NCT00560170
- Testing
- Simvastatin (Zocor), 10mg/10mg of Ezetimibe/Simvastatin (Vytorin)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
NonST Elevation Myocardial Infarction
FAMOUS-NSTEMI MRI Sub-Study
BACKGROUND: Non-ST-segment elevation myocardial infarction (NSTEMI) is the commonest type of acute coronary syndrome (ACS) and has a poor long-term prognosis.
- Trial name
- NCT02073422
- Testing
- Fractional flow reserve, Magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- NHS National Waiting Times Centre Board
Peripheral Arterial Disease
Evaluation of Perfusion and Oxygenation in Muscle of Patients With PAD Undergoing LER
During this IIT, the MSOT (Multispectral Optoacoustic Tomography ) Acuity Echo will be used to scan participants with Peripheral Arterial Disease assess MSOT Multispectral Optoacoustic Tomography (single-wavelength and…
- Trial name
- NCT06645353
- Testing
- MSOT Multispectral Optoacoustic Tomography
- Volunteers
- 55 people
- Sponsor
- Medical University of Graz
Coronary Artery Disease, Post Coronary Artery Bypass Grafting
Aerobic and Resistance Training in Post-CABG Patients
This study investigates the effect of combined aerobic and resistance training using resistance bands on diaphragmatic excursion and pulmonary function (FVC, FEV₁, PEF) in post-CABG patients undergoing phase II cardiac…
- Trial name
- NCT07034937
- Testing
- Combination of aerobic training (treadmill walking) and resistance training
- Volunteers
- 15 people
- Sponsor
- Universitas Padjadjaran
Peripheral Arterial Disease
BEnefit of Arterial Preparation by LONGitudinal Scoring
The purpose of the artery preparation concept is to perform regular longitudinal micro-incisions on the inner side of the artery ("scoring") and therefore promote a regular expansion of atheroma by balloon inflation.
- Trial name
- BELONG (NCT03721939)
- Testing
- FLEX Scoring Catheter
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- VentureMed Group Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.