Clinical trials: Articular Disease
Axial Spondyloarthritis, Psoriatic Arthritis
RAFTLIN-1 Levels in Axial Spondyloarthritis and Psoriatic Arthritis
Unlike other rheumatic diseases, acute phase reactants such as C-reactive protein and erythrocyte sedimentation rate are not diagnostic for patients with Spondyloarthropathies (SpA).
- Trial name
- NCT05771389
- Testing
- serum raftlin-1 protein levels
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Shoulder Injuries, Shoulder Pain
Mitigating the Impact of Shoulder Movement Dysfunction; a Randomized Controlled Trial
The purpose of the proposed work is to screen the effectiveness of an evidence-based, targeted, treatment intervention versus a non-specific, generalized, treatment intervention to treat symptomatic shoulder instability in…
- Trial name
- NCT04852640
- Testing
- Active Rehabilitation Program (ARP), Nonspecific Passive Intervention (NPI)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Osteoarthritis, Muscle Pain
An Bioequivalence Study of Loxoprofen Sodium Patches in Healthy Volunteers
This study was a single-center, randomized, open-label, two-agent, two-cycle, double-cross bioequivalence trial.
- Conditions
- Osteoarthritis, Muscle Pain, Swelling Muscle
- Trial name
- NCT06510413
- Testing
- Loxoprofen Sodium Patches(reference product), Loxoprofen Sodium Patches(test product )
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
Anterior Knee Pain Syndrome
Yoga for Adolescent Knee Pain
Adolescent atraumatic anterior knee pain is a common yet cumbersome diagnosis that is currently managed with home exercises and physical therapy.
- Trial name
- NCT06031935
- Testing
- Yoga
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Frozen Shoulder, Adhesive Capsulitis
Spencer's Technique Versus Mulligan's Technique for Stage II Frozen Shoulder
Stage II frozen shoulder (adhesive capsulitis) is associated with pain, stiffness, restricted shoulder range of motion, and reduced quality of life.
- Trial name
- NCT07844135
- Testing
- Spencer's Muscle Energy Technique With Conventional Physiotherapy, Mulligan's Mobilization With Movement With Conventional Physiotherapy
- Where
- 2 sites in Pakistan
- Volunteers
- 72 people
- Sponsor
- Superior University
Rotator Cuff Lesion, Subacromial Impingement Syndrome
Investigation of the Effect of Central Sensitization Symptom Severity on Steroid Injection Results in Shoulder Pain
The aim of this study was to investigate the effect of the presence and severity of pre-treatment central sensitization on the results of subacromial/ intra-articular shoulder injection in patients with rotator cuff…
- Conditions
- Rotator Cuff Lesion, Subacromial Impingement Syndrome, Shoulder Pain, Chronic Pain
- Trial name
- NCT06404125
- Testing
- Range of Motion of Shoulde Joint, Hand Grip Test, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Knee Osteoarthritis, Hip Osteoarthritis
An Analysis of the Outcomes From Protocolized Perioperative Care for Patients Receiving Total Hip or Knee Arthroplasty
The care for patients receiving total hip and knee arthroplasty at the University of Arkansas for Medical Sciences has followed a structured care pathway since July 2015.
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Knee Arthritis, Hip Arthritis
- Trial name
- NCT03071250
- Testing
- Total knee or Hip Arthroplasty
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Arkansas
Sjogren's Syndrome
Ultra-High Frequency Ultrasonography in Sjögren's Syndrome
Patients diagnosed with a diagnosis of Sjogren's syndrome performed according to the ACR/EULAR criteria will be included in the study.
- Trial name
- UltraSjögren (NCT06338735)
- Testing
- Ultra-High Frequency Ultrasound scan of minor salivary glands
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- University of Pisa
Knee Arthropathy
Defining the Optimal Location to Place an Adductor Canal Block
The aim of the current project is to address a gap in the existing literature related to optimal placement of local anesthetic for an adductor canal (AC) block.
- Trial name
- NCT04298476
- Testing
- Placement of an adductor canal nerve block
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Drexel University
Acromioclavicular Sprain
Platelet-rich Plasma, Corticosteroid, or Lidocaine for Acromioclavicular Joint Pain
This study will compare three different treatment injections for the management of acromioclavicular joint dysfunction (ACJ Dysfunction).
- Trial name
- NCT05161468
- Testing
- Lidocaine injection, Corticosteroid Injection, Protein Rich Plasma(PRP) Injection
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Brooke Army Medical Center
Total Knee Arthroplasty for Gonarthrosis
Analysis of the Functional Impact of Total Knee Arthroplasty Using Quantified Gait Analysis and Proprioceptive Evaluation
Total knee arthroplasty remains the gold standard in the management of disabling gonarthrosis. Improved functional results, increased availability of care and an ageing population have all contributed to the rise in total knee…
- Trial name
- ARTHROPROMA (NCT06907368)
- Testing
- Quantitative Gait Analysis
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Osteoarthritis, Hip
Analysis of a Tapered Porous Coated Stem and a Cementless Hemispherical Acetabular Component
This prospective study will evaluate the hip function and quality of life of patients operated for total hip arthroplasty with Masterloc femoral stem and MPACT acetabular cup.
- Trial name
- NCT03168750
- Testing
- Femoral Component:Medacta Masterloc Stem and Medacta MPACT cup.
- Where
- 3 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Knee Osteoarthritis, Osteoarthritis
"Bimodal vs Unimodal High-Intensity Pulsed Electromagnetic Field Therapy in Older Adults With Knee Osteoarthritis"
This randomized, double-blind clinical trial aims to evaluate the effect of high-intensity pulsed electromagnetic field therapy (HI-PEMF) applied either exclusively on the knee joint or bimodally on the knee and quadriceps, in…
- Conditions
- Knee Osteoarthritis, Osteoarthritis, Osteo Arthritis of the Knee, Gonarthrosis
- Trial name
- HIPEMF-OAK (NCT07198750)
- Testing
- HI-PEMF - Knee (Chronic Pain Protocol), HI-PEMF - Quadriceps (Muscle Strengthening Protocol), Home-Based Exercise Program
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Hospital Civil de Guadalajara
Osteoarthritis
A Study Comparing Ceramic-on-metal Articulation to Metal-on-metal Articulation in Cementless Primary Hip Arthroplasty
The aim of this study is to demonstrate the non-inferiority of the ceramic on metal articulation using M2a-38™ mm cup compared to the metal on metal articulation using the same cup.
- Trial name
- NCT00754520
- Testing
- Ceramic On Metal, Metal on Metal
- Where
- 3 sites in Finland, United Kingdom
- Volunteers
- 213 people
- Sponsor
- Zimmer Biomet
Rheumatoid Arthritis
Antimalarial and Covid 19 in Rheumatoid Arthritis
The antimalarial agent hydroxychloroquine(HCQ) have been used widely used for the treatment of rheumatoid arthritis and systemic lupus erythematosus.
- Trial name
- NCT04389320
- Testing
- Hydroxychloroquine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Adhesive Capsulitis
Spencer's Muscle Energy Technique Along With Strain Counter Strain in Adhesive Capsulitis.
Numerous Physiotherapy techniques have been found to be beneficial but there is no consensus on the best treatment approach for speeding up rehabilitation process and rejuvenating functional capacity in patients suffering from…
- Trial name
- NCT04822324
- Testing
- Spencer Muscle energy technique with conventional Physiotherapy, Strain counter strain along with conventional Physiotherapy and Spencer Muscle energy technique
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Rheumatoid Arthritis
JAKPOT (JAK Inhibitors and Predictors of Outcome in RheumaToid Arthritis)
Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease associated with inflammation and destruction of joints and systemic effects, which result in significant impact on patient's quality of life and function.
- Trial name
- JAKPOT (NCT04084223)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis
Comparative Efficacy and Safety Study of GP2015 and Enbrel® in Patients With Rheumatoid Arthritis
Demonstrate equivalent efficacy of GP2015 and EU-authorized Enbrel in patients with moderate to severe, active (RA) who had an inadequate response to disease modifying anti-rheumatic drugs (DMARD) including methotrexate (MTX).
- Trial name
- EQUIRA (NCT02638259)
- Testing
- GP2015
- Where
- 92 sites in United States, Bulgaria and 14 more
- Volunteers
- 376 people
- Sponsor
- Sandoz
Health Services Accessibility, First-line Treatment
Can Digitally Delivered First-line Osteoarthritis Treatment Improve Equal Access to Care
To improve chronically ill patients' health and quality of life, long-standing and continuous treatment is needed at an acceptable cost.
- Conditions
- Health Services Accessibility, First-line Treatment, Osteoarthritis
- Trial name
- Access (NCT06148779)
- Testing
- Digitally delivered first-line treatment for osteoarthritis, Face-to-face first-line treatment for osteoarthritis
- Where
- Sweden
- Volunteers
- 50,000 people
- Sponsor
- Joint Academy
Shoulder Pain
Effectiveness of Noninvasive Phrenic Nerve Neuromodulation in Shoulder Pain and Hepatobiliary Visceral Comorbidity.
Pain, particularly shoulder pain, is a social and economic problem worldwide. Although visceral pathology is not yet taken into account in the diagnosis of these pains, it is likely that on numerous occasions the hepatobiliary…
- Trial name
- NCT06296979
- Testing
- Phrenic nerve neuromodulation, common Physical therapy
- Where
- 4 sites in Spain
- Volunteers
- 34 people
- Sponsor
- University of Seville
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