Clinical trials: Ascorbic Acid
Diabetes Mellitus, Type 2
Effect of Vitamin C, D and Zinc Supplementation on the Immune and Inflammatory Process in Type 2 Diabetic Subjects
Type 2 Diabetes Mellitus According to the World Health Organization (WHO), there are more than 346 million individuals with diabetes, of which 90% are type 2.
- Trial name
- NCT03734445
- Testing
- Vitamin Supplement
- Volunteers
- 120 people
- Sponsor
- Universidad Autonoma del Estado de Mexico
Vitamin C Deficiency, Acute Disease
A Long-term Study to Describe the Use of PASCORBIN® 7.5 g in Patients With Vitamin C Deficiency
The aim of this long-term observational study is the documentation of the use of PASCORBIN® 7.5 g in patients with vitamin C deficiency.
- Conditions
- Vitamin C Deficiency, Acute Disease, Chronic Disease
- Trial name
- NCT02422901
- Testing
- vitamin C
- Where
- Germany
- Volunteers
- 5,000 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Bioavailability
Comparative Bioavailability of Two Forms of Vitamin C
The purpose of this study is to compare levels of vitamin C in the blood over the 24 hour period following a single 1000 mg dose of vitamin C from ascorbic acid, calcium ascorbate and placebo.
- Trial name
- NCT01852903
- Testing
- calcium ascorbate, ascorbic acid
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- NBTY, Inc.
Multiple Myeloma
Trisenox, Ascorbic Acid and Bortezomib in Patients With Relapsed/Refractory Multiple Myeloma
This is a phase I dose escalation study to estimate the maximum tolerated dose (MTD) of the novel combination of Arsenic, Ascorbic Acid and Velcade, followed by a phase II study conducted using the MTD estimated from the phase I…
- Trial name
- AAV (NCT00590603)
- Testing
- Arsenic Trioxide, Ascorbic Acid and Bortezomib
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Thin Gingival Phenotype
Injectable Platelet-Rich Fibrin and Microneedling With or Without Vitamin C for Gingival Phenotype Augmentation.
This randomized split-mouth clinical trial will evaluate whether adding locally injected vitamin C to injectable platelet-rich fibrin (i-PRF) and microneedling improves gingival tissue thickness and keratinized tissue width in…
- Trial name
- NCT07848035
- Testing
- Microneedling, Injectable Platelet-Rich Fibrin (i-PRF), Vitamin C
- Where
- Yemen
- Volunteers
- 27 people
- Sponsor
- University of Science and Technology, Yemen
Osteoporosis, Vitamin C Deficiency
Link Between ASCorbemia Level and Osteoporosis
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis.
- Conditions
- Osteoporosis, Vitamin C Deficiency, Vertebral Fractures
- Trial name
- ASCO (NCT07660484)
- Testing
- Plasma vitamin C assessment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Anemia in Pregnancy
Effect of Ascorbic Acid Supplementation in Pregnancy on Anemia (AAA)
A. Anemia is a common problem affecting pregnancy and can result in profound consequences to both the mother and the growing fetus. Current treatment usually includes administration of oral or IV iron, or blood transfusions.
- Trial name
- AAA (NCT03564756)
- Testing
- Vitamin C
- Where
- United States
- Sponsor
- Fetal Medicine Foundation
Systemic Lupus Erythematosus (SLE)
Efficacy of Vitamin C Supplementation on Serum IL-6 Levels and Disease Activity in Systemic Lupus Erythematosus Patients
The study aimed to evaluate the efficacy of vitamin C supplementation compared to placebo towards IL-6 levels and disease activity with the MEX-SLEDAI score in Systemic Lupus Erythematosus (SLE) patients.
- Trial name
- NCT07071220
- Testing
- Vitamin C
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Sriwijaya
Leukemia (Both ALL and AML), Cancer of Lung
Changing Over Time of Ascorbic Acid After Chemotherapy
Rationale: Recent studies showed that ascorbic acid (AA) stimulates proliferation and maturation of T lymphocytes and NK cells. Chemotherapy results in depletion of those cells and thereby an increased infection rate.
- Conditions
- Leukemia (Both ALL and AML), Cancer of Lung, Myeloma
- Trial name
- NCT02931942
- Testing
- blood withdrawn
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Ulcerative Colitis
Tolerability and Efficacy of Sodium Picosulfate/Magnesium Citrate Versus PEG/Ascorbic Acid in Ulcerative Colitis Patients
Ulcerative colitis is a chronic condition that results in the inflammation of the colon and rectum. Patients suspected to have ulcerative colitis are diagnosed via colonoscopy.
- Trial name
- NCT03581149
- Testing
- Sodium Picosulfate/Magnesium Citrate Laxative, 2L polyethylene glycol/ascorbic acid
- Where
- Lebanon
- Volunteers
- 68 people
- Sponsor
- American University of Beirut Medical Center
Chronic Rhinosinusitis, Intraoperative Bleeding
Effect of Vitamin C Administration on Intraoperative Bleeding in Patients Undergoing Sinusoscopy
Functional endoscopic sinus surgery (FESS), or sinusoscopy, is a standard surgical procedure used to treat chronic rhinosinusitis and other conditions of the nasal sinuses.
- Conditions
- Chronic Rhinosinusitis, Intraoperative Bleeding, Blood Loss, Surgical
- Trial name
- NCT07866274
- Testing
- Ascorbic acid
- Volunteers
- 78 people
- Sponsor
- Assiut University
Sarcopenia
Effects of L-ARGinine and Liposomal Vitamin C Supplementation On Physical Performance
In older age, reduced mobility is associated with an increased risk of reduced quality of life, disability, institutionalisation, and death, as well as increased healthcare expenditures.
- Trial name
- ARGO (NCT06865261)
- Testing
- Bioarginina C
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
HIV Infections
The Safety and Effectiveness of Different Doses of Vitamin C in HIV-Infected Patients
This is a study to evaluate the tolerance and antiviral effect of oral vitamin C in HIV-infected.
- Trial name
- NCT00001070
- Testing
- Oral Vitamin C
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Alcoholics
Alcohol Abuse or Alcohol Withdrawal: Risk of Latent Scurvy
Scurvy, or latent scurvy, may be underestimated in developed countries, but continue to be described, often as case report. Little is known about the prevalence of vitamin C deficiency in a specific population as withdrawal…
- Trial name
- NCT03467022
- Testing
- Vitamin C
- Volunteers
- 47 people
- Sponsor
- SCP Battistelli
Septic Shock, Sepsis
Triple Therapy in Septic Shock Patients
this study is conducted to evaluate the role of the novel triple therapy combination in reducing the mortality rate, reducing the shock time, and reversal of organ damage.
- Conditions
- Septic Shock, Sepsis, Organ Dysfunction Syndrome Sepsis
- Trial name
- NCT04508946
- Testing
- vitamin c - thiamine- hydrocortisone
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Air Force Specialized Hospital, Cairo, Egypt
Restless Leg Syndrome
Restless Legs Syndrome in Hemodialysis Patients
Restless legs syndrome (RLS) is defined as the spontaneous movement of the limbs (mainly legs) associated with unpleasant - painful sensation which is relieved by moving the affected limb.
- Trial name
- NCT03337529
- Testing
- Vitamin C
- Where
- Lebanon
- Volunteers
- 19 people
- Sponsor
- Makassed General Hospital
Anemia, Peritoneal Dialysis
Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis
People with kidney failure are at risk for the development of anemia. Anemia is a decrease in the production of hemoglobin, a substance that carries oxygen in the blood.
- Trial name
- NCT00920413
- Testing
- Vitamin C
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Unity Health Toronto
Fusion of Spine (Disease)
The Effectiveness of Vitamin C in Postoperative Pain Management of Single-level Posterior Lumbar Interbody Fusion (PLIF)
Postoperative pain management remains a major challenge for surgeons. Despite huge technological advances in pain management, many researchers have documented that unrelieved pain remains common after surgeries, which is…
- Trial name
- NCT02127060
- Testing
- Vitamin C
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Seoul National University Hospital
Colon Cleansing for Colonoscopy
Sodium Picosulphate/Magnesium Citrate and Low-volume PEG -Ascorbic Acid as Preparation for Colonoscopy
Adequate bowel cleansing is essential for effective colonoscopy. Acceptance of colon preparation affects the quality of colon cleansing.
- Trial name
- NCT01603654
- Testing
- sodium picosulphate magnesium citrate, low-volume PEG -ascorbic acid
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- ASST Fatebenefratelli Sacco
Stage I Multiple Myeloma, Stage II Multiple Myeloma
Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma
RATIONALE: Drugs used in chemotherapy, such as arsenic trioxide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma, Refractory Plasma Cell Neoplasm
- Trial name
- NCT00112879
- Testing
- arsenic trioxide, ascorbic acid, dexamethasone
- Where
- United States
- Sponsor
- The Cleveland Clinic