Clinical trials: Ascorbic Acid
Ovarian Cancer, Cervical Cancer
Safety of Antioxidants During GYN Cancer Care
It is known that people with cancer are using antioxidant vitamins at high rates. It is not known if these vitamins are safe to use during cancer treatment.
- Conditions
- Ovarian Cancer, Cervical Cancer, Uterine Cancer
- Trial name
- NCT00284427
- Testing
- vitamin C
- Volunteers
- 25 people
- Sponsor
- Jeanne Drisko, MD, CNS, FACN
Contrast Induced Nephropathy
Contrast Agent-associated Nephrotoxicity in Intensive Care Unit Patients
The use of N-acetylcysteine and ascorbic acid reduce the incidence of radiographic contrast agent induced reduction in renal function in Intensive Care Unit patients.
- Trial name
- ICU (NCT01017796)
- Testing
- N-acetylcysteine and ascorbic acid
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Head and Neck Cancer
Pre- and Postoperative Nutrition in Head and Neck Cancer Patients
The purpose of the project is to investigate the effect of wound healing of a combined pre- and postoperative oral supplement, consisting of zinc, vitamin C, arginine and multivitamin, as a supplement for adequate nutrition in…
- Trial name
- NCT03531190
- Testing
- Nutritional supplement (Protein + MIX), Nutritional supplement (Protein)
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Copenhagen
Shock, Thermal Burn
VItamin C in Thermal injuRY: The VICToRY Trial
This study aims to show that giving high dose, intravenous vitamin C in addition to standard care to burned critically ill patients will be associated with less organ dysfunction, improved survival and a quicker rate of recovery.
- Trial name
- VICToRY (NCT04138394)
- Testing
- Ascorbic Acid
- Where
- 33 sites in United States, Belgium and 7 more
- Volunteers
- 666 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Atrial Fibrillation
Vitamin C and Atrial Fibrillation After Cardiac Surgery
The purpose of this study is to determine if vitamin C decreases the chance of developing atrial fibrillation, a type of arrhythmia or irregular heartbeat, following cardiac surgery.
- Trial name
- NCT01580683
- Testing
- Ascorbic Acid
- Where
- United States
- Sponsor
- Regional Hospital of Scranton
Pyruvate Kinase Deficiency, Glucose 6 Phosphate Dehydrogenase Deficiency
High-Dose Vitamin C in G6PDA and Pyruvate Kinase Deficiency: A Safety Study
This study is testing whether high-dose Vitamin C is safe and well-tolerated in patients with two inherited red blood cell disorders - Pyruvate Kinase Deficiency (PKD) and Class A Glucose-6-Phosphate Dehydrogenase Deficiency…
- Trial name
- G6PDA PKD (NCT07612345)
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Cancer Pain, Quality of Life
Meditation With Virtual Reality for Cancer Pain Relief in the Pain Therapy and Palliative Care Service
Cancer is a disabling, challenging and growing global disease. Although early diagnosis and adequate treatment of oncological disease have been developing rapidly, a large part of the population remains without access to…
- Conditions
- Cancer Pain, Quality of Life, Palliative Medicine
- Trial name
- NCT06328751
- Testing
- Case group, Active control group, Passive control group
- Where
- Brazil
- Volunteers
- 129 people
- Sponsor
- Emily Santos Montarroyos
Hypertension, Cardiovascular Diseases
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
The main purpose of research is to examine and understanding the development of hypertension in obese adults with insulin resistance.
- Trial name
- NCT04715022
- Testing
- Ascorbic acid solution (American Regent Laboratories Inc.), Saline
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Kansas Medical Center
Hypothyroidism, Primary Hypothyroidism
Effect of Vitamin C Supplementation in Patients With Primary Hypothyroidism
Thyroid disease affects almost a quarter of a billion individuals worldwide and more than 50% of them being not aware of this condition.
- Conditions
- Hypothyroidism, Primary Hypothyroidism, Vitamin C Deficiency
- Trial name
- NCT05733078
- Testing
- Vitamin C, Oral Rehydration Salt Formulations
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Dr Adnan Agha
Septic Shock, Sepsis
Ascorbic Acid and Thiamine Effect in Septic Shock
The aim of this study is to evaluate the efficacy of early metabolic resuscitation with combination therapy using vitamin C and thiamine in improving organ function and survival in patients with septic shock.
- Trial name
- ATESS (NCT03756220)
- Testing
- Combination therapy of vitamin C and thiamine, Normal saline solution
- Where
- 6 sites in South Korea
- Volunteers
- 116 people
- Sponsor
- Tae Gun Shin
Cathartic Colon
Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
- Trial name
- NCT02761213
- Testing
- Oral sulfate solution (OSS), 2-L PEG/Asc
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Multiple Myeloma and Plasma Cell Neoplasm
Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Vitamin C may increase the effectiveness of arsenic trioxide by making cancer cells more sensitive to the…
- Trial name
- NCT00006021
- Testing
- ascorbic acid, arsenic trioxide
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Bowel Preparation, Sodium Picosulfate and Magnesium Citrate
Combination Method Using Sodium Picosulfate and Magnesium Citrate and PEG With Ascorbic Acid for Bowel Preparation
The aim of this study is to compare the efficacy depending on the order of the sequential combination method using sodium picosulfate and magnesium citrate (PMC) and PEG with ascorbic acid for bowel preparation.
- Conditions
- Bowel Preparation, Sodium Picosulfate and Magnesium Citrate, Polyethylene Glycol With Ascorbic Acid
- Trial name
- NCT02979223
- Testing
- sodium picosulfate and magnesium citrate, polyethylene glycol with ascorbic acid
- Where
- South Korea
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Septic Shock
Effects of Glucocorticoid Combined With Vitamin C and Vitamin B1 on Microcirculation in Severe Septic Shock
This study aimed to investigate the effect of Glucocorticoid combined with vitamin C and vitamin B1 versus hydrocortisone alone on microcirculation in septic shock patients.
- Trial name
- NCT03821714
- Testing
- Glucocorticoid combination therapy, Glucocorticoid
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Southeast University, China
Depression
Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly.
The trial aims to treat depression. The incidence of major depression in the elderly accounts for between 3.6 and 4.8% and increases to 8 to 37.4% when depressive disorders in general is studied.
- Trial name
- NCT02793648
- Testing
- Ascorbic Acid, Alpha tocopherol
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Yolanda de Diego Otero
Iron Deficiency
Iron Bioavailability From Encapsulated Ferrous Sulphate
Salt is one of the very few regularly purchased food item in all socioeconomic classes including poor remote areas with subsistence farming.
- Trial name
- NCT02353325
- Testing
- non-encapsulated FeSO4, encapsulated FeSO4, before cooking, encapsulated FeSO4, after cooking
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Jaundice
Grape Seed Powder and Vitamin C Supplementation for Liver Disease (Acquired Hepatic Jaundice)
Jaundice is a frequent medical problem that affects people of all ages. It is important to note that jaundice is not an actual sickness as such itself but rather a symptom of liver illness brought on by an increase in the…
- Trial name
- AHJ (NCT07575789)
- Testing
- Grape-C supplement
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- University of Lahore Hospital (ULH)
Iron Absorption in Presence of Polyphenols
Polyphenols in Sorghum and Iron Absorption
Iron deficiency and iron deficiency anemia are two major public health problems in developing countries. In these countries, the use of monotonous plant-based diets, low in animal source food but high in iron absorption…
- Trial name
- NCT01162616
- Testing
- labeled iron solutions
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy Subject, Immunity
The Effect of the Consumption of 4 Botanical Extracts on Immunity in Healthy Adults (B-4-Immune)
This study will evaluate the capacity of botanical extracts to modulate immune mechanisms compared to a placebo group in healthy volunteers.
- Trial name
- B-4-Immune (NCT05117385)
- Testing
- Botanical extract
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Myelodysplastic Syndromes
A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations
This is an open label, Phase Ib study designed to evaluate the safety, toxicity and biological activity of high dose Vitamin C in bone marrow and peripheral blood when administered as therapy to patients with intermediate or high…
- Trial name
- NCT03433781
- Testing
- Vitamin C
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health