Clinical trials: Ascorbic Acid
Cancer
Study of High-Dose Intravenous (IV) Vitamin C Treatment in Patients With Solid Tumors
The primary purpose of this study is to evaluate the safety and tolerability of vitamin C (ascorbic acid) given by injection into the vein.
- Trial name
- NCT00441207
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Midwestern Regional Medical Center
Shock, Thermal Burn
VItamin C in Thermal injuRY: The VICToRY Trial
This study aims to show that giving high dose, intravenous vitamin C in addition to standard care to burned critically ill patients will be associated with less organ dysfunction, improved survival and a quicker rate of recovery.
- Trial name
- VICToRY (NCT04138394)
- Testing
- Ascorbic Acid
- Where
- 33 sites in United States, Belgium and 7 more
- Volunteers
- 666 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Patellar Tendinopathy
Effect of Collagen/Vitamin C in Jumper's Knee; a RCT
Patellar tendinopathy (PT) is a tendon overuse injury with high prevalence rates in elite and recreational athletes. PT sometimes results in a prolonged absence from sport participation, hampering individuals to achieve their…
- Trial name
- Jumpfood (NCT05407194)
- Testing
- Collagen + vitamin C
- Where
- Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Gelderse Vallei Hospital
Coronary Artery Disease
Effect of Grape Seed Extract Plus Ascorbic Acid on Endothelial Function
A pilot study of 15 subjects will be conducted to confirm an acute effect of grape seed extract on endothelial function. We then will perform a a randomized, double blind, placebo controlled crossover study designed to…
- Trial name
- NCT00554242
- Testing
- Grape seed extract and ascorbic acid
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston University
Pregnancy, Smoking
Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women
Women who smoke during their pregnancy place their unborn child at an increased risk of health problems, including decreased lung function and possible lung diseases later in life.
- Trial name
- NCT00632476
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Gingival Hyperpigmentaion
Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation
Vitamin C affect the melanocytes function not the number while diode laser cause melanocytes destruction. Although diode laser and vitamin C have proved their effectiveness in depigmentation in previous studies, there are no…
- Trial name
- NCT03252418
- Testing
- Ascorbic Acid 500 MG, diode laser
- Volunteers
- 10 people
- Sponsor
- Ain Shams University
Metastatic Pancreatic Cancer
High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
The purpose of this study is to see if a combination of paclitaxel protein bound (also known as nab-paclitaxel), gemcitabine, and cisplatin when given with high dose Ascorbic Acid will be safe and effective in individuals with…
- Trial name
- NCT03797443
- Testing
- Ascorbic Acid, nab paclitaxel, Cisplatin
- Where
- 3 sites in United States
- Sponsor
- Piedmont Cancer Institute
Melasma
Comparison Between Efficacy of Topical Tranexamic Acid Vs Topical Ethyl Ascorbic Acid In Treatment Of Melasma
This study is to compare the efficacy of topical tranexamic acid vs topical ethyl ascorbic acid in the treatment of melasma
- Trial name
- NCT07522788
- Testing
- Ethyl ascorbic acid topical application, Tranxemic acid topical application
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
Acne Scars
The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars
Our study involves the evaluation of a high potency chemical peel in its efficacy and safety profile for the treatment of acne scars.
- Trial name
- NCT02126657
- Testing
- 70% glycolic acid
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Catheter-Associated Urinary Tract Infection, Ascorbic Acid
Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries
This open-label randomized trial aims at assessing the role of Vitamin C pills in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT04261036
- Testing
- Ascorbic Acid 1000 mg
- Where
- Lebanon
- Sponsor
- American University of Beirut Medical Center
Schizophrenia, Schizophreniform Disorders
Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants
The purpose of this trial is to study the effect of adding the omega-3 fatty acid EPA and/or Vitamins E + C to antipsychotic drugs in younger patients with schizophrenia and related psychoses.
- Conditions
- Schizophrenia, Schizophreniform Disorders, Schizoaffective Disorder, Psychotic Disorders
- Trial name
- NCT00419146
- Testing
- Ethyl-eicosapentaenoic acid (EPA), Vitamins E + C
- Where
- Norway
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aker
Exercise, Blood Flow Restriction (BFR) Training Effects
Effects of BFR-training on Stem Cells and Immune Cells in Human Skeletal Muscle
In this 3-year project, investigators will first measure stem cells (primary outcome) and immune cells (secondary outcome) in human skeletal muscle immediately after and 24 hour after the BFR-training.
- Conditions
- Exercise, Blood Flow Restriction (BFR) Training Effects, Supplement
- Trial name
- NCT07569627
- Testing
- BFR (180 mmHg), NMN-BFR exercise, Vitamin C-resistance exercise
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Taipei
Vitamin C, Post-mastectomy Pain Syndrome
Vitamin C on Acute and Chronic Post Mastectomy Pain
This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of perioperative vitamin C on acute and chronic post mastectomy pain after breast cancer surgery
- Trial name
- NCT05770596
- Testing
- vitamin C group
- Where
- Egypt
- Volunteers
- 204 people
- Sponsor
- Tanta University
Acne Vulgaris, Acne Scars
Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring
This study aimed to evaluate the efficacy of dermaroller and topical vitamin C- either separate or combined- in treatment of post acne scars.
- Trial name
- NCT03522922
- Testing
- Dermaroller, Topical Vitamin C
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Reperfusion Injury
Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients
It has been shown that the stress that occurs during cardiac surgery leads to early decrease of many of the body's resources such as Vitamin C (ascorbic acid) which may contribute to complications after surgery.
- Trial name
- VitaminC (NCT01167569)
- Testing
- Ascorbic Acid, 5 % Dextrose Water or Normal Saline
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Rutgers, The State University of New Jersey
Oral Mucositis
Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers
The surrounding controversies both advocating and simultaneously opposing the use of vitamin C, mostly extrapolating animal models to human models, it has not been used individually to assess the severity of oral mucositis during…
- Trial name
- NCT02868151
- Testing
- Ascorbic Acid, Zinc acetate
- Where
- India
- Volunteers
- 180 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre