Clinical trials: Ascorbic Acid
Bowel Preparation, Colonoscopy
Bowel Preparation for Colonoscopy in the Elderly
The success of colonoscopy is closely related to the quality of colonic preparation. However, data regarding colonoscopy preparations in the elderly (65 years older) are scarce.
- Trial name
- NCT02290093
- Testing
- Standard full-volume PEG, Split-dose full-volume PEG, Split-dose low-volume PEG
- Where
- 3 sites in South Korea
- Volunteers
- 230 people
- Sponsor
- Kyunghee University Medical Center
Neuropathic Pain
Vitamin C as add-on Therapy in Patients With Acute Herpes Zoster
To compare the efficacy and tolerability of three different doses of Pascorbin® besides standard medication with placebo and the reduction of herpes zoster-associated clinical symptoms as an add-on therapy for patients suffering…
- Trial name
- NCT05561257
- Testing
- Vitamin C
- Where
- 3 sites in Germany
- Volunteers
- 12 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Cirrhosis of the Liver
Composition for Treating Cirrhosis and Liver Cancer (SB-1121)
The composition treats cirrhosis and hepatocellular carcinoma (Hcc) at an early stage. The product is extracted from herbs, including Adenosma glutinosum extract, Eclipta prostrata extract, Phyllanthus urinaria extract, Impatiens…
- Trial name
- SB-1121 (NCT05178303)
- Testing
- SB-1121(1), SB-1121(2)
- Where
- 2 sites in United States, Vietnam
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Nguyen Thi Trieu, MD
Safety and Pharmacokinetics of Intravenous Ascorbate
Evaluation of Intravenous Ascorbic Acid
This Phase I study will be conducted in 2 parts to examine safety and pharmacokinetics of escalating doses of intravenous ascorbic acid (AA) first in healthy volunteers followed by evaluation in oncology subjects.
- Trial name
- NCT01833351
- Testing
- IV Vitamin C
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Hyperoxaluria
Validation Testing for Plasma Oxalate Levels in the Biochemical Laboratory at the Galilee Medical Center, in Collaboration With the Biochemistry Laboratory at CHARITE Hospital in Berlin, and Testing the Relationship Between Oxalate Levels and Vitamin C Levels in Plasma
Background: Elevated plasma oxalate levels in various conditions, including: primary hyperoxaluria due to increased production in the liver, renal failure due to decreased renal excretion, intestinal diseases with fatty diarrhea…
- Trial name
- NCT06578754
- Testing
- This is an non-interventional study
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Vitamin C Deficiency, Vitamin D Deficiency
Vitamin Deficiency and Blood Pressure in Hospitalized Jewish General Hospital (JGH) Patients
There is suggestive evidence that vitamin C and vitamin D deficiency may increase blood pressure across the range of blood pressures from normal to elevated.
- Trial name
- NCT00921622
- Testing
- Vitamin D, Vitamin C
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Jewish General Hospital
Ovarian Cancer, Cervical Cancer
Safety of Antioxidants During GYN Cancer Care
It is known that people with cancer are using antioxidant vitamins at high rates. It is not known if these vitamins are safe to use during cancer treatment.
- Conditions
- Ovarian Cancer, Cervical Cancer, Uterine Cancer
- Trial name
- NCT00284427
- Testing
- vitamin C
- Volunteers
- 25 people
- Sponsor
- Jeanne Drisko, MD, CNS, FACN
Palatally Impacted Canines
Efficacy of Injectable Vitamin C on Accelerating Canine Movement: A Clinical Study
efficacy of the injectable vitamin C to reduce the time of canine traction
- Trial name
- mesotherapy (NCT03260829)
- Testing
- vitamin C
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV Infections
A Study to See if Certain Antioxidants and Vitamins Will Keep Lactate Levels Down in Patients Taking Anti-HIV Drugs
The purpose of this study is to see if certain vitamins (C, E, B1, and B2) can keep lactate levels from becoming too high in patients who are taking nucleoside reverse transcriptase inhibitor (NRTI) anti-HIV drugs.
- Trial name
- NCT00037063
- Testing
- Thiamine hydrochloride, Riboflavin, Ascorbic acid
- Where
- 4 sites in United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Respiratory Distress
the Effect of High Dose Ascorbic Acid on Critically Ill Patients With ARDS
1. To access role of vitamin C supplementation in ARDS patients on the following: Oxidants/ antioxidants imbalance Length of hospital stay Mortality rate Weaning from mechanical ventilator Incidence of adverse drug reaction 2.
- Trial name
- NCT03780933
- Testing
- vitamin c
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Misr International University
Hepatitis B Virus Infection
Inhibition of HBV Replication and Biological Reversal of Cirrhosis (F3-F4) and HCC by Flavonoids
SB Flavonoids for Advanced Liver Disease ManagementSB Flavonoids represents a multi-target therapeutic composition engineered for the comprehensive management of Hepatitis (Acute and Chronic), Advanced Cirrhosis (F3)-(F4), and…
- Trial name
- Flavonoids (NCT07084948)
- Testing
- Flavonoid, Tenofovir
- Where
- 2 sites in United States, Vietnam
- Volunteers
- 134 people
- Sponsor
- Trieu, Nguyen Thi, M.D.
Multiple Myeloma and Plasma Cell Neoplasm
Bortezomib, Ascorbic Acid, and Melphalan in Treating Patients With Newly Diagnosed Multiple Myeloma
RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as melphalan, work in different ways to stop the growth of cancer cells, either by…
- Trial name
- NCT00317811
- Testing
- ascorbic acid, bortezomib, melphalan
- Where
- 8 sites in United States
- Volunteers
- 35 people
- Sponsor
- Oncotherapeutics
Postoperative Pulmonary Complications
Effect of Ascorbic Acid on Postoperative Pulmonary Complications in Patients Undergoing Cardiac Surgery
Postoperative pulmonary complications(PPCs) including, but not limited to ,hypoxemia, pneumonia, ventilator-induced lung injury, and acute respiratory distress syndrome (ARDS),atelectasis,pleural effusion .PPCs may result in…
- Trial name
- NCT03756727
- Testing
- Ascorbic Acid, Saline
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xuzhou Medical University
Complex Regional Pain Syndrome (CRPS) TYPE I
Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery
Vitamin C with its antioxidant role has many indications. The objective of this study is to demonstrate that taking vitamin C as a preventive significantly reduces the occurrence of complex regional pain syndrome (CRPS) type 1 in…
- Trial name
- SDRC (NCT02390505)
- Testing
- Vitamin C
- Where
- 3 sites in France
- Volunteers
- 995 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Metabolism Changes, Vitamin D
Does Vitamin C Increase the Body Heat Generated By The Nervous System?
The goals of this clinical trial are to determine whether or not vitamin C is able to: (1) increase the body heat generated by the sympathetic nervous system; and, (2) increase circulating vitamin D concentration during…
- Trial name
- NCT07341308
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Asthma
Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Combining fish oil and vitamin C supplementation will provide a greater anti-inflammatory effect against developing exercise-induced bronchoconstriction (EIB) than either nutritional supplement alone.
- Trial name
- NCT01057615
- Testing
- Fish Oil, Ascorbic Acid
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
Septic Shock, Ascorbic Acid Deficiency
Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.
This is a retrospective chart review that will measure the impact on outcomes in septic shock patients who were resuscitated with a novel combination of medicines called iHAT (intravenous hydrocortisone -ascorbic acid-thiamine).
- Trial name
- NCT03913468
- Testing
- Intravenous Ascorbic Acid
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- University of Wisconsin, Madison
Pneumonia
Effect of High Dose Intravenous Vitamin C in Severe Pneumonia
This trial is a multicenter, randomized, double-blind, two-arm, parallel-group, placebo-controlled trial to investigate the effect of high dose intravenous (IV) Vitamin C as an adjunct to the standard of care for patients with…
- Trial name
- VICSEP (NCT05842382)
- Testing
- Active Ingredient
- Where
- 3 sites in Malaysia
- Volunteers
- 484 people
- Sponsor
- Clinical Research Centre, Malaysia
Asthma, Pulmonary Function
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIP (NCT06106646)
- Testing
- No active intervention in this protocol (previously randomized to Vitamin C)
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- Oregon Health and Science University
Stroke, Bruises
Prevention and Treatment for Bruises in Patients With Ischemic Stroke
Background Over the past few decades, significant advances have been made in the diagnosis and treatment of strokes. Most studies focus on functional recovery in stroke patients.
- Conditions
- Stroke, Bruises, Skin Lesions
- Trial name
- NCT06823999
- Testing
- Ascorbic acid (Vitamin C)
- Volunteers
- 400 people
- Sponsor
- Chiayi Christian Hospital