Clinical trials: Aspiration, Respiratory
Anesthesia; Functional
Assessment Through Transcutaneous Brain Oximetry (NIRS) of Two Preoxygenation Techniques
Preoxygenation techniques is currently considered a standard of care, but how they influence cerebral oxygenation remains largely unknown.
- Trial name
- NCT04352049
- Testing
- Preoxygenation
- Where
- 2 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña
Upper Resp Tract Infection, Rhinitis Acute
Evaluation of a Hypertonic Seawater Aerosol Therapy Solution in Adults and Children
The purpose of this study is to evaluate the tolerance, the performance and safety of this device, 22‰ Hypertonic seawater aerosol therapy solution in unidose container, to treat adult and peadiatric patients with of upper…
- Conditions
- Upper Resp Tract Infection, Rhinitis Acute, Rhinopharyngitis, Cold Symptom
- Trial name
- AIR (NCT07267689)
- Testing
- Treatment (22‰ Hypertonic seawater aerosol therapy solution)
- Where
- 4 sites in Poland
- Volunteers
- 110 people
- Sponsor
- Laboratoires Gilbert
Non Small Cell Lung Cancer
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (EBUS-TBNA) for Mediastinal Re-staging of Non-small Cell Lung Cancer(NSCLC)
The aim of this study is to determine the diagnostic values of EBUS-TBNA in the mediastinal re-staging after induction treatment in patients with non-small cell lung cancer. Primary objective: 1.
- Trial name
- NCT00859742
- Testing
- EBUS-TBNA, integrated PET/CT
- Where
- South Korea
- Sponsor
- National Cancer Center, Korea
Respiration, Artificial, Laparoscopy
Hemodynamic Effects of Ventilation Modes
Different ventilation modes can be used in laparoscopic surgeries. These surgeries are performed in steep Trendelenburg position with serious hemodynamic disturbances.
- Conditions
- Respiration, Artificial, Laparoscopy, Hemodynamics
- Trial name
- NCT03684291
- Testing
- Mode of Mechanical Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ufuk University
COVID-19
Study to Evaluate the inHaled Recombinant COVID-19 Vaccine (Adenovirus Type 5 Vector) On the Protective-Efficacy in Adults (SeiHOPE)
This phase III clinical trial is an endpoint-driven randomized, double-blind, parallel-controlled, multicenter clinical trial, and around 13,000 subjects aged 18 years and above who have previously received 1 dose of…
- Trial name
- NCT05124561
- Testing
- Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH)
- Volunteers
- healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Bradycardia, Hypoxemia
Nose-close and Abdomen-compression in Pediatric Flexible Bronchoscopy
The nasopharyngeal oxygen (NPO) with Nose-close (NC) and Abdomen-compression (AC) technique may use for support or rescue asphyxiated infants during Flexible bronchoscopy.
- Trial name
- NPO-NC-AC (NCT01629186)
- Testing
- NPO with Nose-close and Abdomen-compression
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- Cho-yu Chan, MD
Rapid Sequence Induction of General Anesthesia, Sellick Maneuver
Sellick Interest in Rapid Sequence Induction
Lung aspiration can occur when a rapid sequence induction of anesthesia is performed (emergency and/or presence of at least one risk factor for regurgitation of stomach contents).
- Conditions
- Rapid Sequence Induction of General Anesthesia, Sellick Maneuver, Acid Aspiration Syndrome, Lung Aspiration
- Trial name
- IRIS (NCT02080754)
- Testing
- effective sellick maneuver
- Where
- France
- Volunteers
- 3,472 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Disabilities Multiple, Obstruction Airway
Training on the Heimlich Maneuver for Mothers of Children With Disabilities
Foreign body obstruction is one of the most common causes of medical emergencies, particularly in childhood, and can lead to fatal outcomes if not treated promptly and correctly.
- Conditions
- Disabilities Multiple, Obstruction Airway, Foreign Body Aspiration
- Trial name
- NCT07699341
- Testing
- Heimlich Maneuver training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Acute Respiratory Failure, Oxygen Inhalation Therapy
External Validation of the BREF Models
Introduction High-flow oxygen therapy is increasingly used to treat acute respiratory failure (ARF). It can reduce intubation rates without increasing mortality.
- Conditions
- Acute Respiratory Failure, Oxygen Inhalation Therapy, Respiratory Distress
- Trial name
- BREF2 (NCT06669312)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Clinico Humanitas
Dysphagia, Aspiration Pneumonia
FEES to Determine Neurological Intensive Care Patients' Oral Diet
Dysphagia is associated with high rates of mortality and morbidity. Adjusting the oral diet of ICU-patients based on flexible endoscopic evaluation of swallowing (FEES) findings might reduce pneumonia rate, mortality and need for…
- Conditions
- Dysphagia, Aspiration Pneumonia, Deglutition Disorders, Intensive Care Neurological Disorder
- Trial name
- NCT03753841
- Testing
- Adjustment of oral diet
- Where
- Germany
- Volunteers
- 125 people
- Sponsor
- University of Giessen
Lymphadenopathy, Lung Cancer
EBUS-TBNA vs Flex 19G EBUS-TBNA
Endobronchial ultrasound (EBUS) guided transbronchial needle aspiration (EBUS-TBNA) is an excellent tool for sampling enlarged mediastinal and hilar lymph nodes, but only provides needle aspirate samples which are often adequate…
- Conditions
- Lymphadenopathy, Lung Cancer, Sarcoidosis, Lymphoma
- Trial name
- NCT02592837
- Testing
- Flexible 19G EBUS-TBNA needle, 21G EBUS-TBNA needle
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Aspiration, Pneumonia
Retrospective Study in Patients Who Have Had a Difficult Intubation.
The investigator wants to investigate if there is an increased risk of postoperative pulmonary problems in patients who have had an intubation where there was need for more than a laryngoscope.
- Trial name
- NCT02576756
- Volunteers
- 1,000 people
- Sponsor
- Universitair Ziekenhuis Brussel
Rds, Pulmonary Hypertension
High Flow Ventilation With Volume Guarantee
The trial is a pilot study performed in the NICU's at Oslo University Hospital and Haukeland University Hospital preparing a multi-center randomized, controlled unblinded cross-over study, comparing high frequency ventilation…
- Conditions
- Rds, Pulmonary Hypertension, Meconium Aspiration Syndrome
- Trial name
- NCT02571231
- Testing
- HFV + and - VG
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Paresis
Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Background: Outpatient continuous interscalene brachial plexus blocks are used to control pain after shoulder surgery, with infusions of 0.125% bupivacaine or 0.2% ropivacaine.
- Trial name
- NCT02059070
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Anesthesiology WSU/DMC-NorthStar
Hemiplegia, Respiratory Function Loss
Effect of Transcutaneous Auricular Vagus Nerve Stimulation Application on Respiratory Functions in Stroke Patients
The purpose of this study is to evaluate the effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation (TAVSS) in improving respiratory muscle strength and function in chronic stroke patients.
- Trial name
- TAVNS (NCT06793800)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Fenerbahce University
Pulmonary Embolism, Embolism
Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Evaluate the safety and efficacy of the Aventus Thrombectomy System for aspiration thrombectomy in subjects with acute pulmonary embolism.
- Conditions
- Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases
- Trial name
- NCT05907564
- Testing
- Thrombectomy
- Where
- 26 sites in United States
- Volunteers
- 120 people
- Sponsor
- Inquis Medical, Inc.
Intensive Critical Unit, Pneumonia
Evaluation of the Effectiveness and Safety of Supratube Device
Purpose of the trial: Trial design: Two-parallel arm, double-blind, individually randomized controlled trial. Primary endpoint: Clinical evaluation of sinus, oropharyngeal, tracheal, bronchial or pulmonary infections during…
- Conditions
- Intensive Critical Unit, Pneumonia, Aspiration, Prevention and Control
- Trial name
- SUPRANAV (NCT03573609)
- Testing
- Supranav
- Where
- Colombia
- Volunteers
- 108 people
- Sponsor
- Fundación Cardiovascular de Colombia
Aspiration Pneumonia, Gastric Volume
Gastric Ultrasound for Preoperative Assessment of Gastric Content in Diabetic Patients
ASA fasting guidelines are only applicable to healthy elective surgery patients. Measuring gastric volume now is not easy, and scintigraphy has remained the gold standard technique for many years.
- Trial name
- NCT04181814
- Testing
- Ultrasound
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Respiratory Complication, Respiration, Artificial
Ventilation in Cardiac Surgery
The purpose of this study is to evaluate prospectively ventilatory practices in the perioperative cardiac surgery period.
- Conditions
- Respiratory Complication, Respiration, Artificial, Anesthesia, General, Bypass, Cardiopulmonary
- Trial name
- VENICE (NCT03255356)
- Testing
- Survey
- Where
- 10 sites in Belgium, Brazil and 8 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Caen
Athletic Performance, Muscle Oxygenation
Effects of Core and Inspiratory Muscle Training on Muscle Oxygenation and Athletic Performance İn Young Soccer Players
The purpose of this randomized controlled trial is to investigate the effects of core training and inspiratory muscle training (IMT) on muscle oxygenation and athletic performance in youth male soccer players aged 15-18.
- Conditions
- Athletic Performance, Muscle Oxygenation, Respiratory Function
- Trial name
- NCT07657065
- Testing
- Core Training Program, Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istinye University
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