Clinical trials: Aspiration, Respiratory
Healthcare Associated Infection
Monitors to Improve Indoor Carbon Dioxide (CO2) Concentrations in the Hospital
Ventilation with fresh outdoor air has recently gained considerable attention as a means to reduce the potential risk of indoor aerosol transmission of respiratory pathogens such as severe acute respiratory syndrome coronavirus 2…
- Trial name
- MICH (NCT04770597)
- Testing
- Aranet4 Home CO2 monitor
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Imelda Hospital, Bonheiden
Non-small Cell Lung Cancer
Role of Rapid On-site Evaluation for Mutational Analysis of EBUS-TBNA Specimens
The purpose of the study is to determine if rapid on-site evaluation of EBUS-TBNA samples can increase the percentage of patients with advanced non-squamous non-small cell lung cancer in whom both pathologic subtyping and…
- Trial name
- NCT01799382
- Testing
- Rapid on-site evaluation, EBUS-TBNA
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Disabilities Multiple
Investigation of the Relationship Between Pulmonary Function and Muscle Strength in Athletes With Disability
To investigate the relationship between respiratory function and core muscles strength in athletes with disabilities and compare with healthy athletes.
- Trial name
- NCT03769480
- Testing
- Muscle strength evaluation and Respiratory function Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
COVID-19
Phase Ⅰ Clinical Trial of a Candidate COVID-19 Vaccine
In this trial, a single-arm, open-label study design will be used to evaluate the safety and tolerability after vaccination with escalating doses of the investigational vaccine (Recombinant COVID-19 Vaccine (chimpanzee adenovirus…
- Trial name
- NCT05706324
- Testing
- Recombinant COVID-19 Vaccine (chimpanzee adenovirus vector) for Inhalation
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wuhan BravoVax Co., Ltd.
Respiration, Artificial
Continuous Measurement of Diaphragm Excursion as a Predictor of Extubation Failure
Background: Patients are put under invasive mechanical ventilation (MV) during respiratory failure because they can no longer breathe in a way that delivers enough oxygen to their body.
- Trial name
- NCT03896048
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Respinor AS
Respiratory Function, Pediatric Anesthesia
Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients
This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia.
- Conditions
- Respiratory Function, Pediatric Anesthesia, General Anesthesia
- Trial name
- NCT07323420
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
COVID-19
A Study to Evaluate the Safety and Immunogenicity of Ad5-nCoV and Ad5-nCoV-IH in CoronaVac Immunized Children and Adolescents
This is a multicenter, randomized, and open-label study to evaluate the immune responses and safety profiles of children aged 6-12 years and adolescents aged 13-17 years receiving Ad5-nCoV (intramuscular injection) or Ad5-nCoV-IH…
- Trial name
- NCT05169008
- Testing
- Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector), Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH)
- Where
- 2 sites in Chile
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Amyotrophic Lateral Sclerosis (ALS)
Humanitarian Device Exemption Post-Approval Study of NeuRx Diaphragm Pacing System for Amyotrophic Lateral Sclerosis
This post-approval study will follow 60 participants who have ALS, documented chronic hypoventilation, and bilateral phrenic nerve function, and who undergo the surgical implantation procedure to receive the NeuRx Diaphragm…
- Trial name
- NCT01605006
- Testing
- NeuRx Diaphragm Pacing System (DPS)
- Where
- 11 sites in United States
- Volunteers
- 97 people
- Sponsor
- Synapse Biomedical
Chronic Obstructive Pulmonary Disease
ACBT and High Frequency Chest Wall Oscillations in COPD Patients
Chronic obstructive pulmonary disease (COPD) patients with mucus hyper secretion tend to demonstrate increased frequency of infective exacerbations and a steeper slope of decline in lung function.
- Trial name
- NCT05424133
- Testing
- High frequency chest wall oscillation, Active cycle of breathing
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Inhalation Pneumonia
PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration
There is actually no consensus in place defining for which patients with suspected inhalation pneumonia antibiotic treatment should be initiated and what the duration of this antibiotic treatment should be.
- Trial name
- PROPASPI (NCT02862314)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Meconium Aspiration Syndrome
Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies
The purpose of this study is to evaluate the role of endotracheal suction on the occurrence of meconium aspiration syndrome in depressed meconium stained babies.
- Trial name
- ETMAS (NCT01758822)
- Testing
- No endotracheal suction
- Where
- India
- Volunteers
- 175 people
- Sponsor
- Lady Hardinge Medical College
COPD
Effectiveness of Chest Wall Mobilization Program in Improving Respiratory Function for Patients With COPD
Patients with severe COPD will be recruited from the Respiratory Outpatient Clinic of Kowloon Hospital. Baseline (pre-intervention) assessment for all recruited subjects will be conducted by one physiotherapist assessor who is…
- Trial name
- NCT04122365
- Testing
- Chest Wall Mobilization Program, Control
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Pulmonary Emphysema, COPD
AeriSeal® System for Lung Volume Reduction in Patients With Advanced Emphysema
The purpose of this study is to assess the procedural and post-procedural safety and efficacy of AeriSeal therapy at up to 4 subsegments during a single treatment session in patients with GOLD Stage III/IV homogeneous or…
- Conditions
- Pulmonary Emphysema, COPD, Lung Diseases
- Trial name
- NCT01181466
- Testing
- AeriSeal System
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Aeris Therapeutics
Airway Anesthesia, Ventilation, Mechanical
The Two-handed Mask Ventilation Study
The goal of this clinical trial is to find out which two-handed face mask ventilation technique is the most effective in delivering oxygen to adult patients with Body Mass Index (BMI) less than 30 kg/m2, able to lie supine, have…
- Trial name
- NCT07735845
- Testing
- V-E two handed mask ventilation technique, C-E two handed mask ventilation technique
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Electric Impedance Tomography, Stress Echocardiography
Stress Echo and Electric Impedance Tomography (EIT) Pilot Study
Electric Impedance Tomography (EIT) is a technique based on the injection of small currents and voltage measurements using electrodes on the skin surface generating cross-sectional images representing impedance change in a slice…
- Conditions
- Electric Impedance Tomography, Stress Echocardiography, Cardiac Output, Ventilation
- Trial name
- NCT01168557
- Testing
- EIT (Electrical Impedance Tomography)
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- RWTH Aachen University
Respiratory Insufficiency, Respiratory Distress Syndrome, Adult
Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet
The aim of this study is to compare two methods of delivery of noninvasive mechanical ventilation (NIV). Since patient compliance and mechanical characteristics of the delivery devices are two fundamental variables in the success…
- Conditions
- Respiratory Insufficiency, Respiratory Distress Syndrome, Adult, Chronic Obstructive Pulmonary Disease, Pulmonary Edema
- Trial name
- NCT00944437
- Testing
- Helmet, Full-face mask
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- University of Parma
Anaesthesia Induction
Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial
Intravenous anaesthesia induction is nowadays considered as gold standard, mainly because of the possibility of the rapid therapeutic intervention while having secured i.v. line.
- Trial name
- Induration (NCT04527757)
- Testing
- Inhalation induction, Intravenous induction
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Brno University Hospital
Healthy
Single Ascending Dose and Multiple Ascending Dose Study of Voriconazole Inhalation Powder in Healthy Adult Subjects
This is a Phase 1 (healthy adult volunteers), 2-part, double-blind, randomized, placebo controlled trial to evaluate the safety and pharmacokinetic (PK) profiles of escalating single doses of Voriconazole Inhalation Powder versus…
- Trial name
- NCT04872231
- Testing
- Voriconazole Inhalation Powder
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- TFF Pharmaceuticals, Inc.
Esophageal Cancer, Lung Cancer
Minimizing Pathologic Aspiration in Patients Undergoing Esophageal and Lung Resections for Cancer
The aim of this study is to reduce pathologic aspiration and pneumonia in the perioperative period by providing an oral care and oral hygiene education to patients preoperatively.
- Trial name
- NCT04251312
- Testing
- Oral Hygiene Education and Oral Hygiene Packets
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Mississippi Medical Center
Aging, Respiration, Artificial
ABC Trial: Awakening and Breathing Controlled
The purpose of this study is to determine the impact of a new RN/RRT (Registered Nurse/Registered Respiratory Therapist) directed 2-step protocol to wean patients off of a ventilator.
- Trial name
- NCT00097630
- Testing
- SAT: Spontaneous Awakening Trial, SBT: Spontaneous Breathing Trial
- Where
- 4 sites in United States
- Volunteers
- 334 people
- Sponsor
- National Institute on Aging (NIA)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.