Clinical trials: Aspiration, Respiratory
Bronchiolitis
Bronchiolitis All-study, SE-Norway
Bronchiolitis is a common lower respiratory disease typically affecting infants and children generally younger than 2 years of age.
- Trial name
- NCT00817466
- Testing
- Racemic adrenaline, Isotonic saline
- Where
- 9 sites in Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Dysphagia, Aspiration
Aspiration in Acute Respiratory Failure Survivors 2
The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.
- Trial name
- NCT05108896
- Testing
- 3-Screenings Protocol, FEES, Tracheal Ultrasound
- Where
- 5 sites in United States
- Volunteers
- 855 people
- Sponsor
- University of Colorado, Denver
Cardiac Arrest
Intra-Arrest-Ventilation in Human Cadavers
The study investigates the influence of non-synchronized bag-device-ventilation and intermittent positive pressure ventilation (IPPV), as recommended in the current resuscitation guidelines of the European Resuscitation Concil…
- Trial name
- NCT06306898
- Testing
- Endotracheal Intubation, Laryngeal tube, Laryngeal mask
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Gerrit Jansen
Depressive Disorder, Anxiety
Enhancing Brain And Mental Health Through Breathing Practice
The purpose of this study is to evaluate the feasibility of a structured breathing intervention in rural and non-rural adolescents diagnosed with anxiety and depression, recruited from outpatient pediatric and child/adolescent…
- Conditions
- Depressive Disorder, Anxiety, Adolescent
- Trial name
- NCT07369752
- Testing
- Breathing Intervention
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Dysphagia, Pneumonia
How Does Dysphagia Assessment in Acute Stroke Affect Pneumonia?
Stroke-associated pneumonia (SAP) is common in acute stroke. A significant risk factor is dysphagia. To identify dysphagia, patients are screened using a bedside tool and those suspected of dysphagia then have a specialist Speech…
- Conditions
- Dysphagia, Pneumonia, Acute Stroke
- Trial name
- NCT04779710
- Testing
- Staff Survey
- Where
- United Kingdom
- Volunteers
- 113 people
- Sponsor
- Manchester Metropolitan University
Hemodynamic Stability, Pulmonary Diseases or Conditions
A Study Comparing Sevoflurane and Propofol in Patients Undergoing Endobronchial Ultrasound Guided Needle Aspiration
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used to obtain samples from mediastinal and hilar lymph nodes or lung parenchymal lesions for diagnostic and staging…
- Conditions
- Hemodynamic Stability, Pulmonary Diseases or Conditions, Complication of Anesthesia
- Trial name
- NCT07338578
- Testing
- propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi
Microaspiration, Acute Respiratory Distress Syndrome (ARDS)
Does Cricoid Pressure Reduce the Risk of Aspiration?
In modern anesthesia practice, the application of cricoid pressure during intubation is not infrequently used with the goal of preventing gastric-to-pulmonary aspiration.
- Conditions
- Microaspiration, Acute Respiratory Distress Syndrome (ARDS), Hospital Acquired Pneumonia
- Trial name
- NCT02058004
- Testing
- Cricoid pressure
- Where
- 2 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Respiratory Insufficiency
Neurally Adjusted Ventilatory Assist (NAVA) in NonInvasive Ventilation (NIV)
Main hypothesis is that Neurally Adjusted Ventilatory Assist (NAVA) allows asynchrony reduction in non invasive ventilation (NIV) in comparison with reference Pressure Support (PSV) mode.
- Trial name
- NCT01426178
- Testing
- Neurally Adjusted Ventilatory Assist in Non Invasive Ventilation (Device)
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Clermont-Ferrand
Bariatric Surgery Candidate, Mechanical Ventilation
Comparison of Two Mechanical Ventilation Modes on Oxygenisation
Comparison the effect of two different mechanical ventilation modes on tissue oxygenization.
- Conditions
- Bariatric Surgery Candidate, Mechanical Ventilation, Hypoxia, Tissue Damage
- Trial name
- NCT04389047
- Volunteers
- 30 people
- Sponsor
- Bagcilar Training and Research Hospital
Mechanical Ventilation
Ventilation With ASV Mode in Children
ASV mode of ventilation is an automatic mode with closed-loop control used for mechanical invasive ventilation in intubated patients. It has been studied in adult patients but not in children.
- Trial name
- NCT03930147
- Testing
- ASV ventilation
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Lausanne Hospitals
Ventilator Weaning
Association Between P0.1 and Extubation Failure in Adult Patients With Acute Hypoxemic Respiratory Failure. A Multicenter Prospective Cohort Study
The goal of this observational study is to learn about the effect of the occlusion pressure during the first 100 miliseconds (P01) over the extubation failure in participants receiving mechanical ventilation for acute respiratory…
- Trial name
- NCT06662201
- Where
- Argentina
- Volunteers
- 256 people
- Sponsor
- Argentinian Intensive Care Society
Environmental Sleep Disorder, Cheyne-Stokes Respiration
Monitoring of the Cerebral Tissue Oxygenation and Perfusion in the Adapting Climber During Sleep in High Altitude
One of the major challenges in adapting to high altitudes is that with increasing altitude sleeping quality declines rapidly. Thus, the night sleep can only provide limited to none regeneration.
- Conditions
- Environmental Sleep Disorder, Cheyne-Stokes Respiration, Altitude Sickness
- Trial name
- PerOxySleep (NCT01465971)
- Where
- Germany
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Goethe University
Apnea, Cardiopulmonary Resuscitation
Head Positions to Open the Upper Airway
Ventilation during basic life support improves survival in cardiac arrest patients significantly. Unfortunately, this is in contrast to the willingness of potential rescuers to perform mouth-to-mouth ventilation.
- Trial name
- NCT00869648
- Testing
- Extension, Neutral head position, Anaesthesiologist's position
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Bronchiectasis Adult, Yoga
Effects of an Online Yoga Program on Exercise Capacity and Quality of Life in Bronchiectasis Patients
Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life.
- Trial name
- YOGA-BR (NCT07540936)
- Testing
- Yoga Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Medipol University Hospital
Acute Mountain Sickness, High Altitude
CO2 Supplement for Treatment of Acute Mountain Sickness
It was reported that up to 76% people who rapidly ascend to the altitude higher than 4500 m without sufficient acclimatization will have AMS which often develops 6-8 hours after reaching at high altitude.
- Conditions
- Acute Mountain Sickness, High Altitude, Inhalation; Gas
- Trial name
- NCT06393998
- Testing
- Breathing with CO2 during daytime and night at high altitude, Sleep and doing exercise test under inhalation of air
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- State Key Laboratory of Respiratory Disease
Out-Of-Hospital Cardiac Arrest
Ventilation Monitoring in OHCA
This is a before-and-after study examining the impact of real-time ventilation monitoring during out-of-hospital cardiac arrest.
- Trial name
- NCT04988906
- Testing
- Zoll Accuvent Ventilation Monitor
- Where
- Canada
- Volunteers
- 412 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cardiac Arrest (CA), In-Hospital Cardiac Arrest
The Ventilation During In-hospital Cardiac Arrest Study
The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult…
- Conditions
- Cardiac Arrest (CA), In-Hospital Cardiac Arrest, Heart Arrest
- Trial name
- VENT-IHCA (NCT06809309)
- Testing
- Positive pressure ventilation during cardiopulmonary resuscitation
- Where
- 11 sites in Denmark, Norway
- Volunteers
- 900 people
- Sponsor
- University of Aarhus
Ventilator Associated Pneumonia
Efficacy of Two Intermittent Subglottic Secretion
The purpose of this study is to determine the efficacy of intermittent subglottic secretion lavage combined with aspiration preventing ventilator associated pneumonia in patients with severe neurological disease
- Trial name
- NCT03871985
- Testing
- Subglottic secretion lavage combined with aspiration, Subglottic secretion aspiration
- Volunteers
- 234 people
- Sponsor
- The First Hospital of Jilin University
Respiratory Failure, Cardiac Failure
Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects on Cardiac Performance
Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assist to spontaneous breathing based on the detection of the electrical activity of the diaphragm.
- Trial name
- NCT00647361
- Testing
- Neurally adjusted ventilatory assist (NAVA) provided by a commercially available mechanical ventilator (Servo i, Maquet Critical Care, Solna, Sweden).
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy Volunteers
AZD5423 Single Ascending Dose Study
The aim of the study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD5423 following single ascending dose administrations in healthy male subjects.
- Trial name
- NCT00963183
- Testing
- AZD5423
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
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