Clinical trials: Aspiration; Liquids
Respiratory Distress
Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation
The stomach of the newborn baby is often emptied soon after birth to prevent breathing problems (respiratory distress). Babies born with meconium-stained amniotic fluid and those with increased secretions associated with birth by…
- Trial name
- NCT00729989
- Testing
- Gastric suctioning
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Stevens
Infertility
Ultrasound Guided Aspiration of Hydrosalpingeal Fluid and IVF-ET Outcomes
The aim of this study is to determine whether the ultrasound guided aspiration of hydrosalpingeal fluid at the time of oocyte retrieval can improve the outcomes of IVF-ET .
- Trial name
- NCT01040351
- Testing
- ultrasound guided aspiration of hydrosalpingeal fluid
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Cairo University
Spinal Muscular Atrophy, Spine Deformity
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects with spinal muscular atrophy (SMA).
- Conditions
- Spinal Muscular Atrophy, Spine Deformity, Scoliosis
- Trial name
- PIERRE (NCT05866419)
- Testing
- ThecaFlex DRx System
- Where
- 21 sites in United States, Germany and 3 more
- Volunteers
- 90 people
- Sponsor
- Alcyone Therapeutics, Inc
Pulmonary Aspiration
Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor (GLP-1 RA) Agonist Prior to Anesthesia
The purpose of this study is to determine if prolonged fasting from solids and transitioning to a CLD for 24 hours is protective to decrease RGC in patients on GLP-1 RAs presenting for upper endoscopy, to determine if prolonged…
- Trial name
- NCT06654219
- Testing
- GLP-1 RA users with prolonged fasting instructions, GLP-1 RA users with standard NPO instructions
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- The University of Texas Health Science Center, Houston
Infertility
Salpingectomy Versus Aspiration of Hydrosalpingeal Fluid Prior to IVF-ET
The aim of this randomized controlled trial is to compare the efficacy of ultrasound guided aspiration of hydrosalpingeal fluid with salpingectomy in the management patients with ultrasound visible hydrosalpinges undergoing…
- Trial name
- NCT02008240
- Testing
- Needle aspiration of hydrosalpinx, Salpingectomy
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Aljazeera Hospital
Dysphagia, Stroke
Reduction of Aspiration Through Cohesive Thin Liquids (CTL) in Patients With Mild Oropharyngeal Dysphagia
The aim of the trial is to identify any systematic effect of cohesiveness on the efficacy of swallowing in patients having dysphagia problems.
- Trial name
- NCT02522351
- Testing
- Cereal extract concentration 1, Cereal extract concentration 2, Cereal extract concentration 3
- Where
- 2 sites in Belgium, France
- Volunteers
- 35 people
- Sponsor
- Société des Produits Nestlé (SPN)
Medullary Thyroid Carcinoma, Nodular Goiter
Calcitonin in Needle Wash Using Electrochemiluminescence Method For Diagnosis Of Medullary Thyroid Carcinoma.
Medullary thyroid carcinoma (MTC) is a tumor originating from parafollicular C cells of the thyroid. (1) Representing 1 to 7% of all thyroid carcinoma cases (2, 3, 4).
- Trial name
- NCT06067594
- Testing
- Fine Needle Aspiration Cytology (FNAC) procedure+calcitonin measurement
- Where
- Argentina
- Volunteers
- 155 people
- Sponsor
- Austral University, Argentina
Meconium Aspiration Syndrome
Interleukin-6 in the Development of Meconium Aspiration Syndrome in Newborn
This trial is intended to assess the serum levels of interleukin-6 as a predictive factor for the occurrence of meconium aspiration syndrome in infants born with MSAF.
- Trial name
- NCT07394322
- Testing
- serum interleukin 6
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Breathing
Diagnostic Accuracy of the Central Venous Pressure (CVP) Variation to Predict Fluid Responsiveness in Spontaneously Breathing Patients
Volume expansion (VE) is often administered in intensive care (ICU)-patient to improve arterial oxygen delivery. Such effect is secondary to an increase in stroke volume and cardiac output.
- Trial name
- VPVC (NCT03780660)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Lille
Meconium Aspiration Syndrome
Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies
The purpose of this study is to evaluate the role of endotracheal suction on the occurrence of meconium aspiration syndrome in depressed meconium stained babies.
- Trial name
- ETMAS (NCT01758822)
- Testing
- No endotracheal suction
- Where
- India
- Volunteers
- 175 people
- Sponsor
- Lady Hardinge Medical College
Pancreas Cyst
DNA-mutation Analysis in Cyst Fluid of Suspected Intraductal Papillary Mucinous Neoplasia of the Pancreas
Diagnostic tools are needed to identify mucinous cysts for further evaluation or follow-up respectively to identify cysts with HGD or invasive cancer at an early stage for surgical resection.
- Trial name
- NCT03820531
- Testing
- Next Generation Sequencing, CEA and lipase, Cytology
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Theresienkrankenhaus und St. Hedwig-Klinik GmbH
CSF Circulation
Influence of Yogic Breathwork on CSF Circulation
The purpose of this research study is to determine the influence of yoga breathing practices on cerebrospinal fluid (CSF) circulation, and to find out primarily if a regular practice of 8-week yoga breathing would enhance CSF…
- Trial name
- CSF (NCT03858309)
- Testing
- Breathing Group 1, Breathing Group 2
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
ARDS, Human, Aspiration Pneumonia
Potential Biomarkers and Pathogenic Mechanism for Reflux Aspiration-induced Lung Injury.
There is limited research on aspiration pneumonia-induced ARDS (Acute Respiratory Distress Syndrome), and currently there is a lack of studies on corresponding biomarkers and pathogenic mechanisms.
- Trial name
- NCT06164639
- Testing
- aspiration, bronchial alveolar fluid, EIT V/Q test
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Shanghai Zhongshan Hospital
Postoperative Cardiorespiratory Failure
Hypertonic Saline-hetastarch in Cardiac Surgery
Cardiopulmonary bypass(CPB) is associated with increased fluid extravasation and edema formation. A continuous infusion of a mixture of hypertonic saline/hydroxyethyl starch (HSH)during CPB reduced fluid extravasation and total…
- Trial name
- HH (NCT00469716)
- Testing
- Hypertonic saline (7.2%) hetastarch (6 %)(200/0.5)
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Intraventricular Hemorrhage
ACTIVE Study - Use of ACTIVE Fluid Exchange to Treat Intraventricular Hemorrhage
Randomised controlled trial evaluating active irrigation using IRRAflow device in patients with intraventricular hemorrhages (IVH).
- Trial name
- NCT05204849
- Testing
- IRRAflow, Standard ventriculostomy
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- University of Aarhus
Respiration Disorders, Swallowing Disorder
Artificial Intelligence in Diagnosing Dysphagia Patients
In this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device.
- Conditions
- Respiration Disorders, Swallowing Disorder, Phonation Disorder, Stroke
- Trial name
- NCT05098808
- Testing
- Acoustic features (from signals obtained during phonation)
- Where
- South Korea
- Volunteers
- 449 people
- Sponsor
- The Catholic University of Korea
Meconium Aspiration Syndrome
Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration Syndrome
The purpose of the study is to evaluate the role of routine suctioning of the oropharynx before the delivery of shoulders in preventing breathing difficulty and subsequent lung disease in babies born through meconium stained…
- Trial name
- MSAF-OPS (NCT01328483)
- Testing
- Intrapartum Oropharyngeal Suctioning
- Where
- India
- Volunteers
- 540 people
- Sponsor
- Lady Hardinge Medical College
Deep Sedation, Respiration, Artificial
Fluid Leakage Past Tracheal Tube Cuff : Effect of Suctioning Manoeuvre
The leakage of oropharyngeal secretions around high-volume low-pressure tracheal tube cuffs is usually considered as a major risk factor for bacterial tracheal colonization and subsequent development of ventilator-associated…
- Trial name
- NCT01170156
- Testing
- Hi-Lo Evac tube (Mallinckrodt Inc, USA) (Instilled blue dye)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier de Roanne
Ovarian Neoplasms, Ovarian Cancer
OveRcoming immunosupprEssion aNd rebAlancing the Immune reSponSe in ovAriaN CancEr Study
Ovarian cancer (OC) is one of the most lethal cancers in the world due to late-stage disease at diagnosis. Standard therapy consists of debulking surgery and chemotherapy.
- Conditions
- Ovarian Neoplasms, Ovarian Cancer, Ovarian Carcinoma, Immune Suppression
- Trial name
- RENAISSANCE (NCT06611072)
- Testing
- Bone marrow aspiration, Vena puncture, Peritoneal fluid
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gynaecologisch Oncologisch Centrum Zuid
Aspiration; Liquids, Fasting
Gastric Emptying of Maltodextrin Solution in Elderly and in Adults
Gastric volume will be measured before, 5, 30, 60, 90 and 120 min after drinking 450ml of maltodextrin in young adults and elderly.
- Conditions
- Aspiration; Liquids, Fasting, Perioperative Pulmonary Aspiration
- Trial name
- GEMA (NCT04288466)
- Testing
- maltodextrin
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brasilia University Hospital