Clinical trials: Aspiration
Inadequate or Impaired Breathing Pattern or Ventilation
Supreme LMA and Proseal LMA in Prone Anesthetized Patient
There is no significant difference about success rate of two devices.
- Trial name
- SPLMA (NCT01814306)
- Testing
- Supreme LMA, Proseal LMA
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Bronchopulmonary Dysplasia
Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm Infants
Bronchopulmonary dysplasia (BPD) remains one of the most common complications in extremely preterm infants despite advances in neonatal intensive care.
- Trial name
- EPIRESP (NCT07771387)
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pulmonary Aspiration, Emergency Surgery
Aspiration Risk Assessment by Gastric Ultrasound in eMErgency Surgery and ANesThetic Decision-making: The ARGUMENT Study
Pulmonary aspiration of gastric contents is a serious patient safety problem accounting for 50% of anesthesia-related mortality.
- Trial name
- NCT06303492
- Testing
- GUS
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
COVID-19
Inhaled Ivermectin and COVID-19
Coronavirus disease-19 is global healthcare crisis. Till May 20, 2020, there were approximately 4,789,205 cases and 318,789 related mortalities were identified globally.
- Trial name
- CCOVID-19 (NCT04681053)
- Testing
- Ivermectin Powder
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Nitrous Oxide, Electroencephalography
Effect of Nitrous Oxide on EEG
Our recent preclinical observations suggest that monitoring of slow electroencephalogram (EEG) oscillations may be used to predict the efficacy of rapid-acting antidepressants such as ketamine or nitrous oxide.
- Conditions
- Nitrous Oxide, Electroencephalography, Anesthetic, Inhalation
- Trial name
- HUMANOID (NCT04884893)
- Testing
- Nitrous Oxide
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Glucose Homeostasis, Protein Metabolism
The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease
Background: Glucocorticoids are primary stress response hormones released from the adrenal gland when an individual is under stress.
- Conditions
- Glucose Homeostasis, Protein Metabolism, Lipid Metabolism, Respiratory Function
- Trial name
- NCT01143493
- Where
- United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Yoga
Ultrasound Imaging of the Diaphragm During Yoga Breathing
INTRODUCTION The practice of yoga in recent years is becoming more common. Originating in India, yoga combines physical postures with a philosophy of life and breathing (pranayama).
- Trial name
- NCT05330026
- Testing
- Diaphragm´s study during yoga breathing
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Pulmonary Disease, Chronic Obstructive
Safety, Tolerability and Pharmacokinetics (PK) Study of GSK2269557 in Healthy Subjects
GSK2269557 is being developed as an anti-inflammatory and anti-infective agent for the treatment of inflammatory airways diseases.
- Trial name
- NCT03189589
- Testing
- GSK2269557 500 µg, GSK2269557 750 µg
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fasting, Delayed Gastric Emptying
Gastric Assessment of Pediatric Patients Undergoing Surgery
The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastric emptying in the…
- Conditions
- Fasting, Delayed Gastric Emptying, Aspiration Pneumonia, Respiratory Aspiration of Gastric Content
- Trial name
- NCT05674643
- Testing
- Gastric Ultrasound Baseline Scans, Acetaminophen Absorption Test (AAT), Gastric Ultrasound Serial Scans
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Children, Breathing Patterns
Animation-Based Breathing Therapy for School-Age Children
This randomized controlled trial aims to investigate the efficacy of animation-based breathing therapy on the physical (cough strength, chest expansion, and walking speed) and psychological health (perceived stress level…
- Conditions
- Children, Breathing Patterns, Stress, School Health
- Trial name
- NCT06988254
- Testing
- Animation-based breathing therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Fibromyalgia
Breathing and Chest Wall Mobility in People With Fibromyalgia.
The aim of this study is to examine differences between respiratory function in female fibromyalgia patients and healthy controls. The study will also examine differences in spine mobility and pain intensity.
- Trial name
- NCT03495687
- Where
- Sweden
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Cardiac Arrest
Intra-Arrest-Ventilation in Human Cadavers
The study investigates the influence of non-synchronized bag-device-ventilation and intermittent positive pressure ventilation (IPPV), as recommended in the current resuscitation guidelines of the European Resuscitation Concil…
- Trial name
- NCT06306898
- Testing
- Endotracheal Intubation, Laryngeal tube, Laryngeal mask
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Gerrit Jansen
Airway Obstruction, Foreign-Body, Cardiopulmonary Resuscitation
Cardiopulmonary Resuscitation and Choking Management Education for Caregivers of Infants Under 1 Year: Comparison Between Practical Workshop and Informational Leaflet
Objective: to evaluate the effectiveness of an educational workshop versus standard information in improving knowledge and perceived self-efficacy in basic life support.
- Conditions
- Airway Obstruction, Foreign-Body, Cardiopulmonary Resuscitation, Infant, Health Education
- Trial name
- NCT07567638
- Testing
- Explanation of the informational sheet, Theoretical-practical workshop
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Parkinson's Disease
Cough According to Stimulus Type in PD
Aspiration pneumonia (APn) occurs at a higher rate in patients with Parkinson's disease (PD) versus healthy adults. This is of particular public health concern given that death secondary to aspiration pneumonia and lung infection…
- Trial name
- NCT02390089
- Testing
- Capsaicin vapor, fog, Videofluoroscopic swallow evaluation
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Florida
Airway Aspiration, Cardiopulmonary Arrest
The Impact of Soiled Airway Management on CPR Quality
Regurgitation is an adverse event common during cardiopulmonary resuscitation (CPR) and occurs in 20%-32% of patients experiencing out-of-hospital cardiac arrest (OHCA).
- Trial name
- NCT05278923
- Testing
- SALAD simulation device
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Head and Neck Neoplasms, Swallowing Sparing IMRT
The SWOAR Trial Sparing of Swallowing and Aspiration Related Organs at Risk & Submandibular Gland With Intensity Modulated Radiotherapy Versus Standard IMRT in Head and Neck Squamous Cell Carcinomas
The aim of SWOAR TRIAL is to test sparing of Dysphagia/ Aspiration risk structures (DARS) and contra lateral submandibular gland by IMRT.
- Trial name
- SWOAR (NCT05187091)
- Testing
- Swallowing and submandibular sparing IMRT, Standard IMRT with medical CRT/RT, Cisplatine
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Critical Illness
Effect of Early Physical Exercise on Pulmonary Ventilation and Recruitment
In the critically patient bed rest and immobilization are some of the responsable of the development of respiratory complications.
- Trial name
- EFRA (NCT02226406)
- Testing
- A: Chair - Leg Cycle ergometer, B: Chair - Arm Cycle ergometer, C: Walk in place
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Breathing, Lung Function Decreased
Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function
This study will examine the relationship of airways resistance measured by oscillometry with ventilation defects measured by Phase Resolved Functional Lung (PREFUL) MRI in healthy human subjects.
- Conditions
- Breathing, Lung Function Decreased, MRI Imaging, Healthy
- Trial name
- PROOF (NCT07614685)
- Testing
- Airway Oscillometer, Phase Resolved Functional Lung MRI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Post COVID-19
Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
When the literature search is conducted, it is seen that there are many studies examining the effects of COVID-19 disease on individuals in various disease groups (MS, stroke, Parkinson, COPD, asthma, etc.) and age groups (adult…
- Trial name
- PEPICov (NCT05282043)
- Testing
- Evaluation of Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University