Clinical trials: Assessment
Healthy Adult Participants
Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults
This is a single ascending dose study of L608 in healthy participants and is being conducted to evaluate the safety of L608 with dose level ranging from 10 μg to 20 μg.
- Trial name
- NCT06429930
- Testing
- L608 Liposomal inhalation suspension
- Where
- New Zealand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pharmosa Biopharm Inc.
Influenza, Human
A Study to Evaluate the Bioequivalence of Over-encapsulated Oseltamivir Capsules to Marketed Oseltamivir Capsules in Healthy Volunteers
This is a study in healthy adult volunteers to assess the bioequivalence of over-encapsulated oseltamivir capsules to commercially available oseltamivir capsules. Both formulations will be administered in the fasting state.
- Trial name
- NCT01258530
- Testing
- over-encapsulated oseltamivir, oseltamivir
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
The Aim of This Study is to Evaluate the Effects of Acute Exercise on Serum Oncostatin M Levels in Healthy, Recreationally Active Males
Exercise-Induced Changes in Serum Oncostatin M Levels in Recreationally Active Males
The aim of this study was to compare the effects of workload-matched acute moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) on serum OSM levels on a cycle ergometer in recreationally…
- Trial name
- NCT07195630
- Testing
- Moderate-Intensity Continuous Exercise, High-Intensity Interval Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy
Tolerability, Safety and Pharmacokinetic Study Of Mianhuahua Flavonoids Tablets in Healthy Adult Subjects
The purpose of this study is to determine the safety and tolerability, and to evaluate the pharmacokinetic characteristics of Mianhuahua Flavonoids Tablets after oral administration in healthy adult subjects.
- Trial name
- NCT02622230
- Testing
- Mianhuahua Flavonoids Tablets
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xinjiang Uygur Pharmaceutical Co., Ltd.
Medical Device Site Injury, Pressure Injury
Prevent Medical Device-Related Pressure Injury
Medical Device-Related Pressure Injury (MDRPI) is a localized skin and/or subcutaneous tissue injury that occurs due to the pressure exerted by devices used for diagnostic or therapeutic purposes, taking the form of the medical…
- Trial name
- NCT06563830
- Testing
- educational application
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Osteoarthritis, Knee
Evaluation of the Effectiveness of Manual Therapy in Patients With Knee Osteoarthritis
The aim of this study is to investigate the effects of three different applications (Manual therapy, electrotherapy and home program) on long-term pain, joint range of motion and, secondarily, the functional level of the knee.
- Trial name
- NCT06329128
- Testing
- Experimental: Study Group, Active Comparator: Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
MTBI - Mild Traumatic Brain Injury, Concussion, Mild
Controlled DTI Evaluations in High School Football and Female Soccer to Evaluate Efficacy of Jugular Compression Collar
The purpose of the study is to monitor longitudinal changes in brain structure between the preseason and postseason, in a population of football and soccer playing athletes wearing the Device and compared to a similar population…
- Trial name
- NCT04068883
- Testing
- Q collar
- Where
- 2 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Invasive Aspergillosis
Evaluation of Immediate Release Tablet
Single dose comparison of liquid and solid formulation, followed by study of effect of high fat breakfast. Evaluation of multiple dose pharmacokinetics and tolerability
- Trial name
- NCT02808741
- Testing
- F901318 SDD, F901318 IR, F901318 IR Fasting
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- F2G Ltd
Opioid Use Disorder
Social Functioning in Opioid Use Disorder
Problems with social functioning are core to opioid use disorder (OUD), though specific, modifiable social functioning targets and how they relate to OUD treatment outcomes are poorly understood.
- Trial name
- OUD (NCT07044466)
- Testing
- CBT4CBT-Buprenorphine
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healthy Subjects
A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects
The primary purpose of this first-in-man study is to investigate whether AC-084 is safe and well-tolerated when orally administered at single- and multiple-ascending dose to healthy adults
- Trial name
- NCT02905253
- Testing
- AC-084
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy Participants, Nutrition Intervention
Implementation and Evaluation of Nutrition Interventions
This project aims to implement and evaluate two multi-component dietary interventions focused on promoting healthy and sustainable eating behaviors and preventing weight gain among Flemish higher education students.
- Conditions
- Healthy Participants, Nutrition Intervention, Higher Education Students
- Trial name
- EATFITS (NCT06876272)
- Testing
- Healthy eating promoting programme
- Where
- 4 sites in Belgium
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
COPD, Asthma
Pathogenetic Mechanisms of Chronic Obstructive Pulmonary Diseases
Asthma and chronic obstructive pulmonary disease(COPD) are common diseases, which tend to even increase in many countries. Both from a clinical and a pathophysiological point of view, this is an important issue.
- Trial name
- CAPTA (NCT01378039)
- Testing
- comparison of treatment effect on different markers
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Development and Validation of Gut Permeability Sensor, Permeability; Increased
Fluorescence Spectroscopy for Gut Permeability Assessment
This research aims to develop portable devices - known as fluorescence spectrometers - to monitor the leakage of fluorescent dyes out of the gut into the blood stream.
- Conditions
- Development and Validation of Gut Permeability Sensor, Permeability; Increased, Celiac Disease, Inflammatory Bowel Diseases
- Trial name
- GutPerm (NCT03434639)
- Testing
- Spectroscopic gut permeability test
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Overweight, Obesity
Study to Learn About How the Study Medicines Called PF-07976016 and PF-06882961 Are Taken Up by the Body, and if Either of Them Change How the Body Processes the Other Medicine in Otherwise Healthy Adults With Overweight or Obesity
The purpose of this study is to see how two study medicines, PF-07976016 and danuglipron, taken together affect the level of each other in the blood of participants who have overweight or obesity.
- Trial name
- NCT06910839
- Testing
- PF-07976016, PF-06882961
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Pfizer
Blood Pressure, Body Composition
ENRICH Nurse-Family Partnership Study
The overarching goal of the proposed study is to develop and test an enrichment to Nurse-Family Partnership (NFP) using an existing, evidence-based program to improve clients' and their children's cardiovascular health from early…
- Conditions
- Blood Pressure, Body Composition, Blood Sugar, Body Weight
- Trial name
- NCT05798039
- Testing
- ENRICH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Coronary Artery Disease, Physical Activity
Lifetime Endurance Exercise to Prevent Coronary Artery Disease
The primary objective of the Master@Heart Trial is to investigate whether lifelong endurance exercise reduces the incidence of non-calcified plaques (both mixed and soft plaques) as compared to late-onset endurance exercise and a…
- Conditions
- Coronary Artery Disease, Physical Activity, Lifestyle
- Trial name
- MASTER@HEART (NCT03711539)
- Where
- 3 sites in Belgium
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Irritable Bowel Syndrome
Investigation of Acupoint in Irritable Bowel Syndrome Based on Biological Characteristics
Irritable bowel syndrome (IBS) is a common functional disorder of the digestive system characterized by recurrent abdominal pain associated with bowel movements or changes in bowel habits.
- Trial name
- NCT06365801
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Huntington Disease, Tardive Dyskinesia
A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects
This is a single-center, randomized, double-blinded, placebo-controlled, dose escalation trial to evaluate the safety, tolerability and pharmacokinetic of LPM3770164 sustained-release tablets orally administered in healthy…
- Trial name
- NCT05238701
- Testing
- LPM3770164 sustained release tablet, LPM3770164 sustained release tablet simulant
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Blood Pressure
Evaluation of the Effect of Sodium Bicarbonate Water on Blood Pressure in Normotensive Subjects
ROX_TENSIO18 is a randomised cross-over trial and the main objective is to evaluate the effect of daily consumption of sodium bicarbonate water for 15 days on blood pressure.
- Trial name
- ROX_TENSIO18 (NCT04282512)
- Testing
- Sodium bicarbonate-rich mineral water
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- My Goodlife SAS
Mild Cognitive Impairment
Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
The prevalence of dementia will double in the next three decades in the U.S.; effective treatment or prevention for dementia is urgently needed.
- Trial name
- NCT05948930
- Testing
- Progressive aerobic exercise, Adaptive cognitive training, Combined
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
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