Clinical trials: Assessment Time
Constipation
Assessment of Whole Gut Transit Time Using the SmartPill Capsule
Our null hypothesis states that the two techniques (Sitzmarks radioopaque markers and SmartPill) are equivalent and is demonstrated if the study population shows a correlation of 0.7 or higher.
- Trial name
- WholeGut (NCT00603707)
- Where
- 8 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- The SmartPill Corporation
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Analgesia
Assessment of the Effect of Age on Duration of Analgesia From Single-shot Femoral Nerve Blocks
Cohort study to examine the effect of age on duration of analgesia in patients receiving single-shot femoral nerve block prior to surgery, by postoperative phone follow-up questionnaire.
- Trial name
- NCT04495413
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Heart Rate, All-day Steps
Assessing the Effect of Cool Roofs on Health Using Smartwatches in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Heart Rate, All-day Steps, Distance Walked, Active Minutes
- Trial name
- REFLECT (NCT06571019)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Cytomegalovirus Infections
A Study of Safety and Immune Response to Different Doses of a Cytomegalovirus Vaccine in Healthy Adults
The purpose of this study is to assess the safety, reactogenicity and immune response of the candidate CMV recombinant protein subunit (CMVsu) vaccine consisting of a combination of glycoproteins B (gB) and pentamer antigens…
- Trial name
- NCT05089630
- Testing
- Pentamer (low)/gB(low)/Adjuvant vaccine, Pentamer (med)/gB(low)/Adjuvant vaccine, Pentamer (med)/gB(med)/Adjuvant vaccine
- Where
- 18 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Development of LIFU for Clinical Purposes
Investigation of the Duration of Low-intensity Focused Ultrasound
This project examines the effects of various durations of noninvasive neuromodulation on muscle contractions. The investigators believe this study will help to better understand noninvasive brain stimulation techniques that may…
- Trial name
- NCT05147103
- Testing
- Low-Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Dry Eye Syndrome
Evaluation of Tear Osmolarity Over Time With Sustained Use of Thera Tears Lubricating Drops
The objective of the study is to demonstrate a change in osmolarity over time when moderate to severe dry eye subjects are treated with TheraTears lubricating drops.
- Trial name
- AKORN (NCT02758327)
- Testing
- TheraTears Lubricating Eye Drops
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Koffler Vision Group
Endothelial Function
Study of Vascular Function Before vs After Smoking an E-cigarette as Compared to a Normal Cigarette
Investigation of the effect of one-time use of an electronic e-cigarette in comparison to smoking a conventional cigarette on in vivo conduit endothelial function in healthy long-term smokers
- Trial name
- ECIG-8 (NCT05598125)
- Testing
- electronic cigarette (e-cigarette), conventional tobacco cigarette
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- GWT-TUD GmbH
Colitis, Ulcerative
A First Time in Human Study to Evaluate the Safety and Tolerability of GSK4381406 in Healthy Participants
This is a 3-part First Time in Human (FTIH) study to evaluate the safety, tolerability, and pharmacokinetics (PK) profile of GSK4381406 following administration of single ascending doses (Part 1), repeat ascending doses (Part 2)…
- Trial name
- NCT05999708
- Testing
- GSK4381406, Indomethacin
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Neuromuscular Performance, Reaction Time
Effects of Virtual Reality Exergaming on Reaction Time, Physical Performance, and Muscle Activity in Children
This randomized controlled trial will investigate the immediate effects of virtual reality (VR) exergaming on reaction time, physical performance, balance, and muscle activity in children aged 10-14 years with different athletic…
- Conditions
- Neuromuscular Performance, Reaction Time, Postural Balance
- Trial name
- PED-VR-EMG (NCT07916155)
- Testing
- Immersive Virtual Reality Exergaming
- Where
- Romania
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
User-Computer Interface, Clinical Skills
Establishing Learning Curves in Virtual Simulation Training of Mastoidectomy
The purpose of this study is to establish learning curves of mastoidectomy training in virtual surgical simulation training, to establish the long-term effect of repeat simulation training and to explore the transfer of skills…
- Conditions
- User-Computer Interface, Clinical Skills, Motor Skills, Temporal Bone
- Trial name
- NCT01966185
- Testing
- Tutor function on
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy
A Study With an Open-Label Active Control to Evaluate the Potential of Nestorone® to Delay Cardiac Repolarization in Healthy Female Volunteers
The purpose of the study is to evaluate the effect of Nestorone (NES) administered as an bolus injection on the corrected QT interval using Fridericia's formula (QTcF).
- Trial name
- NCT02236026
- Testing
- Supratherapuetic dose of Nestorone, Moxifloxacin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Population Council
Physical Activity, Self Efficacy
A Video Chat Intervention for Enhancing Self-efficacy for Lifestyle Physical Activity
The purpose of this study is to evaluate the efficacy of three, brief (10-minute) theory-guided video chats for increasing self-efficacy for lifestyle physical activity versus a time-matched video chat comparison group designed…
- Conditions
- Physical Activity, Self Efficacy, Working Adults
- Trial name
- NCT03906955
- Testing
- Efficacy for Lifestyle PA, Efficacy for Work-life Balance
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Tuberculosis
First Time in Human (FTIH) Safety and Pharmacokinetics (PK) Study of GSK3036656 in Healthy Subjects
GSK3036656 is being developed by GSK for the treatment of tuberculosis (TB). This is the FTIH study for GSK3036656 to evaluate the safety, tolerability and PK of single ascending and repeat oral doses of GSK3036656 in healthy…
- Trial name
- NCT03075410
- Testing
- GSK3036656
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Non-Melanoma Skin Cancer (NMSC), Benign Skin Growth
Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically
The primary objective of this study is the evaluation of the efficacy of the tissue oxygen imager based on PpIX DF in differentiating benign skin growth from non-melanoma skin cancer (NMSC).
- Trial name
- PPIX (NCT07201376)
- Testing
- Ameluz 10% Topical Gel, Protoporphyrin IX
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Physical Activity, Sedentary Behavior
School Intervention to Promote Physical Activity and Reduce the Sedentary Time of Low-income Children Aged 6-13 Years
This study is realized in 2 primary schools in the city of Tarbes (France), located in a disadvantaged neighbourhood : 352 children are included in the study.
- Conditions
- Physical Activity, Sedentary Behavior, Children, School-based Intervention
- Trial name
- NCT03983447
- Testing
- School-based intervention to promote PA and reduce ST
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Pau and Pays de l'Adour
Obstetric Labour, Premature, Premature Ejaculation
A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.
A study conducted on healthy volunteers to determine the safety, tolerability and affect on the human body by experimental drug GSK557296.
- Trial name
- NCT00549211
- Testing
- GSK557296
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hepatitis B
Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection
This Phase 1/2a multiple part study is a first time-in-human (FTIH) study designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of single (Part 1) and repeat doses (Part 2) of GSK3965193 in healthy…
- Trial name
- NCT05330455
- Testing
- GSK3965193, Bepirovirsen
- Where
- 14 sites in Canada, France and 4 more
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Children
The Laryngeal Mask Airway (LMA) Unique and the Air-Q Intubating Laryngeal Airway (ILA) in Pediatric Patients
The air-Q® intubating laryngeal airway (ILA) is an supraglottic device used for both airway maintenance during routine anesthesia and as a conduit for tracheal intubation for patients with a difficult airway.
- Trial name
- NCT01314248
- Testing
- each child will receive both the LMA and ILA
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Sedentary Lifestyle, Diabetes Mellitus, Gestational
The Blossom Project: "BlossomUP" Methods to Decrease Sedentary Time in Pregnancy
Multiple studies have demonstrated a very low prevalence of women meeting physical activity and weight gain recommendations during pregnancy.
- Trial name
- BUP (NCT02909725)
- Testing
- Limit accumulation of sedentary time, Walk, Normal daily routine; Usual Care
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Iowa State University