Clinical trials: Assessment Time
Childhood Obesity, Well-Being, Psychological
Generation Healthy Kids: A Cluster-randomized Trial of a Multi-component, Multi-setting Intervention
The GHK intervention was developed according to the United Kingdom Medical Research Council's framework for developing and evaluating complex interventions.
- Conditions
- Childhood Obesity, Well-Being, Psychological, Physical Inactivity, Sleep
- Trial name
- GHK (NCT05940675)
- Testing
- Food and Nutrition, Physical Activity (FitFirst), Sleep and screen media
- Where
- 2 sites in Denmark
- Volunteers
- 1,372 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cystic Fibrosis (CF)
MRI Assessment of Lung Airways in Cystic Fibrosis: Evaluate MRI's Ability to Detect Changes in Airway Structure .
This study is being done to determine whether MRI can produce high quality lung and airway images in healthy and CF patients and if MRI can be used to evaluate size and shape of the airways with computer assistance.
- Trial name
- UTE Airway MR (NCT07454681)
- Testing
- Advanced ultrashort echo time (UTE) MRI - Ultrashort echo time (UTE) imaging is a technique that can quickly capture the fast-decaying 1H lung signal., Multiple Breath Wash out (MBW)
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Physical Inactivity, Overweight or Obesity
eMOTION Formative Study
The eMOTION Study is a two-part ORBIT model phase 1 trial. The first part, called the Formative Study, will assess acceptability and feasibility of a novel physical activity intervention in adults at increased risk for cancer due…
- Conditions
- Physical Inactivity, Overweight or Obesity, Cancer
- Trial name
- NCT06125964
- Testing
- Intensity-Based Goals, Affect-Based Goals, TYPE/CONTEXT Enhancement
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Celiac Disease, Coeliac Disease
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole
This is a 3-part first time into human study (FTIH) study for GSK3915393. Parts A and B of the study will evaluate the safety, tolerability and pharmacokinetics (PK) of single ascending and repeat oral doses of GSK3915393 in…
- Trial name
- NCT04604795
- Testing
- GSK3915393 Capsules, GSK3915393 Solution for Infusion, Itraconazole
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Virus Diseases
A Study of the Safety of and Immune Response to Varying Doses of a Vaccine Against COVID-19 in Healthy Adults
The purpose of this study is to assess the safety, reactogenicity and immune response of a self-amplifying mRNA (SAM) lipid nanoparticle (LNP) platform with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike…
- Trial name
- NCT04758962
- Testing
- 1 µg CoV2 SAM (LNP)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Cancer, Aging
Real-time Behavioral Interventions
The goal of this study is to adapt an evidence-based sedentary behavior reduction intervention for men and women living in Alabama and determine its feasibility, acceptance, and limited efficacy.
- Conditions
- Cancer, Aging, Comorbidities and Coexisting Conditions
- Trial name
- NCT04457128
- Testing
- Just-in-Time Adaptive Intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Respiratory Tract Infections
Safety And Pharmacokinetics Study Of PF-04287881 In Healthy Adults
The purpose of this study is to determine the safety, tolerability and pharmacokinetics of PF-04287881 after a single oral dose in healthy adult volunteers.
- Trial name
- NCT00793000
- Testing
- PF-04287881
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pfizer
Hepatitis B
First Time in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of GSK3389404 in Healthy Subjects
This study is a Phase 1, randomized, double-blind (Sponsor unblinded), placebo controlled, dose escalation study to determine the safety, tolerability and pharmacokinetics (PK) profile of GSK3389404 as single (Part 1) and…
- Trial name
- NCT02647281
- Testing
- GSK3389404
- Where
- 2 sites in United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Rhinitis, Allergic, Seasonal
An Investigation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2245035 in Healthy Volunteers and Allergic Rhinitics.
GSK2245035 is a highly selective Toll-like Receptor 7(TLR7) agonist capable of preferentially inducing the production of interferon alpha (IFNα) versus tumor necrosis factor alpha (TNFα).
- Trial name
- NCT01480271
- Testing
- 2 ng GSK2445053, 20ng GSK2445053, 100ng GSK2445053
- Where
- Netherlands
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Breast Cancer
Margin Optimisation Using Z-axis Assessment With Real-time Tomosynthesis (MOZART Study).
Breast-conserving surgery is commonly performed to remove early-stage breast cancer or ductal carcinoma in situ (DCIS). During surgery, the goal is to completely remove the tumour with a clear margin of normal tissue around it.
- Trial name
- MOZART (NCT07426809)
- Testing
- Standard 2D Specimen Mammography, Mozart 3D Specimen Radiography System
- Where
- Ireland
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Influenza
A Study to Evaluate the Immune Responses of Subunit Influenza Vaccine in Healthy Adults
This is a prospective, open-label, parallel time-cohort study designed to characterize the humoral and cellular immune responses induced by a subunit influenza vaccine (manufactured by Ab\&B Bio-tech Co., Ltd.JS) in healthy…
- Trial name
- NCT07854392
- Testing
- Group A, Group B
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
Temporomandibular Joint and Muscle Disorder
An Implementation and Biobehavioral Study of Temporomandibular Joint and Muscle Disorder (TMJMD)
With the great economic costs and traditionally poor outcomes among chronic temporomandibular joint and muscle disorder (TMJMD) patients, it has become important to treat patients in the acute state, in order to prevent these…
- Trial name
- NCT00952900
- Testing
- Biobehavioral, Active Coping/Attention Intervention
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Leishmaniasis
Safety, Tolerability and Pharmacokinetics (PKs) Investigation of GSK3186899 in Healthy Subjects
The purpose of this study is to evaluate the safety, tolerability and PK profile of single and repeat ascending doses of GSK3186899 in healthy subjects.
- Trial name
- NCT03874234
- Testing
- GSK3186899
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Health Risk Behaviors
Core Endurance in Healthy Young Adults
This study aimed to examine the effect of core endurance levels on upper extremity function, muscle strength and reaction time in healthy young adults.
- Trial name
- NCT06260540
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Healthy Participants
A Study to Examine the Acceptable Taste and to Estimate the Amount of Atazanavir and Cobicistat in the Body When Taken as a Combination Product Versus When Taken as Separate Products at the Same Time
The purpose of this study is to compare the amount of Atazanavir (ATV) and Cobicistat (COBI) in the bodies of healthy adult participants when taken as a combination formulation, and when ATV is administered as an oral powder at…
- Trial name
- NCT04263350
- Testing
- Atazanavir/Cobicistat, Reyataz Atazanavir, Cobicistat
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Internet Gaming Disorder
Investigation of the Relationship Between Internet Gaming Disorder and Sensorimotor Functions in Adolescents
Using computer for long have been shown to cause vision problems, musculoskeletal pain particularly in neck, postural deviations, obesity and physical inactivity in several studies.
- Trial name
- NCT04631523
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Degenerative Lumbar Spine Diseases
Remote Intelligent Interactive Virtual Reality Assessment in Patients With Degenerative Lumbar Spine Diseases
This study will combine virtual reality (VR) technology with machine learning to focus on functional movement. Patients' symptoms will be evaluated, and exercise instruction with real-time feedback will be provided.
- Trial name
- NCT05425680
- Testing
- Core muscle training
- Where
- 2 sites in Taiwan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Reproductive Medicine
Application of Deep Learning to Jointly Assess Embryo Development to Improve Pregnancy Outcome of Embryo Transfer
Aim of this research is to apply the deep learning automation based on Time-lapse imaging to jointly assess embryo development，so that it can ensure the consistency of embryo evaluation and improve the accuracy of evaluation.
- Trial name
- NCT05671601
- Testing
- Automatic picture recognition, Manual Assessment Group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Infections, Rotavirus, Rotavirus Vaccines
To Evaluate Safety & Reactogenicity of GSK Bio's Human Rotavirus (HRV) Vaccine in Filipino Infants at Least 6 Weeks of Age at First Vaccination
GSK has submitted a registration file for its live attenuated oral human rotavirus (HRV) vaccine in several countries. In view of its registration in the Philippines, the present study will collect data on the safety of the…
- Trial name
- NCT00353366
- Testing
- Rotarix, Data collection
- Where
- 18 sites in Philippines
- Volunteers
- 1,439 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline