Clinical trials: Assessment Time
Anesthesia
Prediction of Hypotension During Induction of General Anesthesia
Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents.
- Trial name
- NCT06078228
- Testing
- Propofol - Fentanyl- Atracurium
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
HIV Infections
First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4011499 in Healthy Participants
This FTIH study aims to evaluate the safety, tolerability and PK of the novel investigational Human immunodeficiency virus (HIV)-1 capsid inhibitor VH4011499 in healthy adults.
- Trial name
- NCT05393271
- Testing
- VH4011499, Midazolam
- Where
- 2 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Respiratory Tract Infection, Infections, Bacterial
A Three-Part Study Of GSK580416 In Healthy Subjects
Studies for GSK580416 have been completed in rats and dogs. The main toxic effects seen in animals affected the digestive system and blood cells. Study OPS106400 will be the first administration of GSK580416 in humans.
- Trial name
- NCT00427141
- Testing
- GSK580416
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Menopause, Thrombophilia
Effect of DT56a (Femarelle) on the Coagulation System in the Treatment of Postmenopausal Women
The purpose of this study is to determine if Femeralle (DT56a) has an effect on the coagulation system, measured by platelet adhesion and aggregation, of normal and thrombophilic postmenopausal women.
- Trial name
- NCT00883272
- Testing
- DT56a (Femarelle) [Se-cure pharmaceuticals, Dalton, Israel]
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Influenza
A Study to Evaluate the Immune Responses of Subunit Influenza Vaccine in Healthy Adults
This is a prospective, open-label, parallel time-cohort study designed to characterize the humoral and cellular immune responses induced by a subunit influenza vaccine (manufactured by Ab\&B Bio-tech Co., Ltd.JS) in healthy…
- Trial name
- NCT07854392
- Testing
- Group A, Group B
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
Premature Ejaculation
Effect of Exercise on Premature Ejaculation
Premature ejaculation (PE) is one of the prevalent disorders in men; its leading sequel such as lack of self-confidence, anxiety, depression and unsatisfactory intercourse in men and their partners.
- Trial name
- NCT02984592
- Testing
- physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Jaundice, Deep Learning
A Prospective Study: Smart Phone Application for Measure Serum Bilirubin Through Sclera Images
The primary efficacy endpoints are the standard deviation and coefficient of determination (R2) between predicted and actual values for the bilirubin regression model, and the grading accuracy for the jaundice severity…
- Conditions
- Jaundice, Deep Learning, Hyperbilirubinemia, Sclera
- Trial name
- NCT06421844
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Meningococcal Infection
Duration of hSBA Response After a Primary Series of Bivalent rLP2086 Followed by a Booster Dose
This study is to assess the longevity of immune response in adolescents for approximately 48 months after receipt of a primary series of bivalent rLP2086 vaccination, which is then followed by a booster dose and an assessment of…
- Trial name
- NCT01543087
- Testing
- blood sampling, bivalent rLP2086
- Where
- 56 sites in United States, Czechia and 4 more
- Volunteers
- 698 people, healthy volunteers welcome
- Sponsor
- Pfizer
ACL Injury
Real-time Sensorimotor Feedback for Injury Prevention in Males Assessed in Virtual Reality
Even though females are 2- to 10-times more likely to suffer an anterior cruciate ligament (ACL) injury, males represent the largest population of total ACL injuries.
- Trial name
- MaNMT (NCT04068701)
- Testing
- MaNMT Biofeedback
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Safety and Tolerability
Phase 1 Clinical Study of JMKX003142 Tablets
Phase I clinical study to evaluate the safety, tolerability, and pharmacokinetic characteristics of JMKX003142 tablets administered randomly, double-blind, placebo-controlled single and multiple times in healthy adult subjects…
- Trial name
- NCT06079541
- Testing
- JMKX003142 will be administered orally
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Jemincare
Myopia, Obesity
Trial of a Novel Family-Based Intervention to Increase Outdoor Time and Fitness
This study aims to implement a new family-based health behavior community program to increase time spent outdoors and physical activity among Singapore children aged 6 to 12 years in a 1-year randomized clinical trial.
- Trial name
- FIT (NCT01388205)
- Testing
- Family-based Outdoor program
- Where
- Singapore
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Sunburn, Erythema, Sun Protection
UV Exposure Assessed With Wearable Sensor and Sun Protection
The goal is to prevent ultraviolet light (UV) overexposure by providing consumers with relevant, easy-to-access, specifically actionable information.
- Trial name
- NCT03344796
- Testing
- Goal attainment
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Attention Deficit, Hyperactivity Disorder
Brain Activity Associated With Inhibition of Action in Attention-deficit
Inhibitory control allows individuals to suppress unwanted actions and to resist irrelevant stimuli. It is thought to be a core deficit in Attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- INHIB'MOV (NCT04768556)
- Testing
- EEG experimental sessions 1, EEG experimental sessions 2
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Temporomandibular Joint and Muscle Disorder
An Implementation and Biobehavioral Study of Temporomandibular Joint and Muscle Disorder (TMJMD)
With the great economic costs and traditionally poor outcomes among chronic temporomandibular joint and muscle disorder (TMJMD) patients, it has become important to treat patients in the acute state, in order to prevent these…
- Trial name
- NCT00952900
- Testing
- Biobehavioral, Active Coping/Attention Intervention
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Malocclusion
Evaluation of a "Flash-free" Adhesive Resin for Orthodontic Bracket Bonding
The purpose of this study is to compare bonding time, bond survival, amount of adhesive remaining on the tooth surface after bracket debonding, and time required for adhesive remnant cleanup between a new "flash-free" and a…
- Trial name
- NCT02030002
- Testing
- APC Flash-Free Adhesive Coated Appliance System, APC II Adhesive Coated Appliance System
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diabetes Mellitus, Type 2
Single, Ascending Dose, First Time in Human Study for GZR18 in Healthy Subjects
Single ascending dose first time in human study for GZR18 in healthy subjects
- Trial name
- NCT05328726
- Testing
- GZR-18
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Sleep, Physical Fitness
Fitness and Sleep in People With Family History of Type 2 Diabetes.
Currently, it is not known if the amount of nighttime sleep has any effect on the overall physical fitness, and on how much energy do people who have a relative with type 2 diabetes (parent, sibling, or grandparent) use to…
- Conditions
- Sleep, Physical Fitness, Type 2 Diabetes
- Trial name
- NCT00721084
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Sedentary Behavior, Cognitive Impairment
A Physical Activity Program to Disrupt Sedentary Time in Older Latinos
To test the feasibility of an intervention designed to replace sedentary time with physical activity in older Latinos, delivered in their homes to improve cognitive function and brain connectivity.
- Trial name
- PAIS (NCT04507464)
- Testing
- Ecological Momentary Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Pneumonia
Evaluation of Ventilatory Strategies During Laparoscopic Surgery
Atelectasis involving declive areas often occurs during general anesthesia and may persist postoperatively. This phenomenon could be amplified by pneumoperitoneum and Trendelenburg position.
- Trial name
- NCT01923038
- Testing
- First arm: patients ventilated with zero end expiratory pressure, Patients ventilated with Positive End Expiratory Pressure, Patients ventilated with Positive End Expiratory Pressure plus Recruitment maneuver
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maria Vittoria Hospital
Pregnancy
Evaluation of the Efficacy of the Becoming Parents Program
The primary aim of this study is to test the effectiveness of the Becoming Parents Program--a couple focused educational program for couples having a first child--on individual and couple well being and the parent-infant…
- Trial name
- NCT00243997
- Testing
- Becoming Parents Program
- Volunteers
- 940 people, healthy volunteers welcome
- Sponsor
- University of Washington