Clinical trials: Assisted Reproductive Technology
Pain, Oocyte Retrieval
Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF Patients
This is a randomized controlled trial evaluating the efficacy of preoperative analgesic medications - Indomethacin (100 mg per rectum) and Paracetamol/Acamol (1,000 mg intravenously) - for pain management during oocyte retrieval…
- Trial name
- NCT07536425
- Testing
- Indomethacin 100Mg Suppository, Paracetamol / Acetaminophen
- Where
- Israel
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Adenomyosis
Adenomyosis and ART
The goal of this clinical trial is to: Prospectively investigate the association of Adenomyosis with fertility outcomes in relation to COH protocols for ART (long or ultra- long protocol) with a preventive high-dose…
- Trial name
- ADENOFERT (NCT05937490)
- Testing
- Enantone, Dienogest 2 MG (milligram), long GnRH agonist or flexible GnRH antagonist protocol.
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Role of Vitamin D in IVF for Better Outcome
Vitamin D as a Prognostic Marker on Assisted Reproductive Technologies Outcomes.
Studying the effect of Vitamin D administration on assisted reproductive outcomes in women undergoing Intra Cytoplasmic Sperm Injection (ICSI) by giving a dose of vitamin D and determining the effect of this dose on both the…
- Trial name
- NCT05091203
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Female Infertility Due to Advanced Maternal Age
Mitochondrial Energy Production in ART (Assisted Reproductive Technology )
Oocyte maturation requires a lot of energy, which is provided by the mitochondria via the synthesis of ATP. The majority of patients with advanced maternal age (AMA) have poor egg quality.
- Trial name
- Mitenergy (NCT02727400)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Infertility
Sperm Selection for Infertility Treatment (SSA)
Infertility is considered a disease by the World Health Organization and it is increasing worldwide affecting more than 70 million couples. About 50% of the cases are due to male inability to fertilize the oocyte.
- Trial name
- SSA (NCT02867111)
- Testing
- Sperm Selection Assay, Attractant Substance, ICSI
- Where
- 2 sites in Argentina
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
Infertility Assisted Reproductive Technology
fertiShare Evaluation
Sharing bad news (SBN) is a daily challenge for fertility staff and patients. Bad news happens at all stages of fertility care and includes e.g., diagnosing infertility, reporting unexpected, repeated, or definitive treatment…
- Trial name
- NCT06587360
- Testing
- fertiShare intervention - sharing bad news eLearning course, fertiShare control - basic communication skills eLearning course
- Where
- 5 sites in United Kingdom
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Reproductive Techniques, Assisted, DNA Methylation
First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization
To determine whether using DNA methylome to select embryos can increase the live birth rate.
- Trial name
- NCT05442125
- Testing
- Using DNA methylome to select embryos, Using morphologic score to select embryos
- Where
- 28 sites in China, Thailand
- Volunteers
- 1,146 people, healthy volunteers welcome
- Sponsor
- Shandong University
Fertilization in Vitro
Ejaculation Abstinence Time and Assisted Reproductive Technology Outcomes
The goal of this clinical trial is to learn if reducing the ejaculation abstinence time can improve the outcome of assisted reproductive technology.
- Trial name
- NCT06410417
- Testing
- Shorten abstinence time
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Infertility
Maternal and Fetal Compatibility in Assisted Reproductive Technology (ART)-Oocyte Donor Influences Live Birth Rate
Has the maternal KIR haplotype an impact in pregnancy, miscarriage and live birth rates per embryo transfer in donor oocytes -ART by paternal and oocyte donor HLA-C?
- Trial name
- NCT02718105
- Testing
- KIR HLAC determinations
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Infertility, Obesity
IVF Outcome After Bariatric Surgery
This case-control study compares IVF results and live birth rates in women undergoing IVF with a history of bariatric surgery as compared to 2 age-matched control groups composed of (A) non-operated women matched on cases'…
- Trial name
- NCT02884258
- Where
- France
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Clinique Mathilde
Infertility, Female
Endometrial Compaction in Assissted Reproduction
To record the dynamic change of endometrial thickness (Day of embryo transfer Versus. Day of ovulation trigger administration in case of fresh cycles or end of estrogen phase in frozen cycles), and to investigate the impact of…
- Trial name
- NCT04962789
- Testing
- transvaginal ultrasound on the uterus
- Where
- Egypt
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fetal Growth Restriction (FGR), Preeclampsia
Association of Assisted Reproductive Technologies Parameters With the Perinatal Outcome
The goal of this prospective cohort study is to examine how different parameters of assisted reproductive technologies (ART) are associated with the perinatal outcome in individuals with singleton or multiple gestations.
- Conditions
- Fetal Growth Restriction (FGR), Preeclampsia, Stillbirth, Placenta Previa
- Trial name
- NCT06918236
- Where
- 6 sites in Bulgaria, Greece and 1 more
- Volunteers
- 12,084 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
IVF Cycle, Ovarian Stimulation
Efficacy and Safety of Medication Used to Stimulate Ovulation
Individuals undergoing In Vitro Fertilization must undergo controlled ovarian hyperstimulation (COH) to produce enough quality eggs for fertility treatment.
- Conditions
- IVF Cycle, Ovarian Stimulation, Egg Retrieval, Pregnancy
- Trial name
- NCT02715336
- Testing
- Ovulation induction with hCG and Lupron (GnRH agonist)
- Where
- Canada
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Create Fertility Center
Infertility Assisted Reproductive Technology
The Impact of Uterine Immunity and Its Alterations on the Embryo Implantation Process
Evaluation of uterine immunity, histological picture, and endometrial microbiome for embryo implantation
- Trial name
- UTIMEE (NCT07120958)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Momo Fertilife
HIV
HIV Physician's Survey
This is a survey study to assess the variability in the current management of pregnancy, reproductive care and assisted reproductive technologies for HIV-positive individuals in Canada to estimate interest for further projects.
- Trial name
- NCT01104974
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Ectopic Pregnancies
Activin A and Inhibin A in Predicting Outcome of Pregnancies of Unknown Location After Assisted Reproductive Technology
The purpose of this study is to determine the predictive value of a single serum determination of activin A and inhibin A for the prognosis of ectopic pregnancy after in Vitro Fertilization (IVF) cycles, in both native and…
- Trial name
- NCT01589016
- Where
- Spain
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertilities
Comparison of the Efficiency of Intra-uterine Insemination and in Vitro Fertilization in Women Over 37 Years
As age increases the chances for a woman to become pregnant decrease as well spontaneously as through assisted reproductive technologies (ART).
- Trial name
- AMPAGE (NCT02001870)
- Testing
- In Vitro Fecundation (IVF), Intra Uterine Insemination (IUI)
- Where
- 12 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Infertility
Use of Nitric Oxide Metabolites for Predicting Embryo Quality in In-Vitro Fertilization (IVF)
Improvements in In-Vitro Fertilization (IVF) outcomes have largely been due to the generation of excess embryos allowing for multiple embryo transfer.
- Trial name
- NCT00788619
- Testing
- Transfer of embryos on day 3 or day 5 after fertilization., Day 5 transfer
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Infertility
The Role of Progesterone and PIF for Successful Implantation and On-going Pregnancy in Assisted Reproductive Technology
The aim of this study is to achieve a more profound understanding of the endocrine alteration in luteal progesterone level after gonadotrophin stimulated IVF/ICSI cycles and to explore the optimal progesterone level needed for…
- Trial name
- NCT02129998
- Testing
- IVF/ICSI treatment
- Where
- Denmark
- Volunteers
- 873 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Assisted Reproductive Techniques
Double Stimulation in Women With Low Prognosis in ART
The main objective of this study is to compare the cumulative ongoing pregnancy rates of two different IVF protocols in women candidate for ART characterized by low prognosis.
- Trial name
- NCT04531644
- Testing
- double stimulation, conventional ovarian stimulation
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital