Clinical trials: Atelectasis
Pulmonary Atelectasis
Fraction of Inspired Oxygen and Atelectasis in Children
Investigators hypothesized that maintaining low fraction of inspired oxygen would be beneficial to prevent anesthesia-induced atelectasis in mechanically ventilated children undergoing general anesthesia.
- Trial name
- NCT02870842
- Testing
- Lung ultrasound, Respiratory management
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Respiratory Distress Syndrome, Newborn
Randomized Controlled Trial of Surfactant Administration by Laryngeal Mask Airway (LMA)
In this protocol we will conduct a randomized controlled trial where babies with respiratory distress syndrome (RDS) who have not yet reached criteria for intubation, will be randomized to receive surfactant by LMA or to continue…
- Trial name
- NCT00599651
- Testing
- Surfactant administered via Laryngeal Mask Airway (LMA), standard of care (nasal CPAP and supplemental oxygen)
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- University of Virginia
Pain, Postoperative, Pulmonary Atelectasis
Paravertebral Block Versus Erector Spinae Plane Block for Modified Radical Mastectomy in Womens.
postoperative pain following Modified radical mastectomy is severe specially after dissection of tissues .paravertebral plane block provides an excellent postoperative analgesia for women's,but it carry the risk of pneumothorax…
- Conditions
- Pain, Postoperative, Pulmonary Atelectasis, Mastectomy
- Trial name
- NCT03614091
- Testing
- Erector spinae plane block, Paravertebral plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preterm Birth, Respiratory Distress Syndrome
Surfactant Nebulization for the Early Aeration of the Preterm Lung
Respiratory distress syndrome is the most common cause of respiratory failure in preterm infants. Treatment consists of respiratory support and exogenous surfactant administration.
- Conditions
- Preterm Birth, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- SUNSET (NCT04315636)
- Testing
- Surfactant nebulisation
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- University of Zurich
Chemical Injury, Chemicals; Intoxication
The Medical Management in Patients Exposed to Weapons of Mass Destruction
Observation study measuring medical response in contaminated environment.
- Conditions
- Chemical Injury, Chemicals; Intoxication, Acute Respiratory Distress Syndrome, Distress Respiratory Syndrome
- Trial name
- CBRNEObs (NCT05026645)
- Testing
- Clinical interventions performed in acute settings (contaminated environment), Protection (clinician and patient), Decontamination (clinician and patient)
- Where
- 15 sites in United States, Canada and 4 more
- Volunteers
- 1,000 people
- Sponsor
- St. Justine's Hospital
Atelectasis, Postoperative
Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass
This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary…
- Trial name
- NCT07432477
- Testing
- Single Step Lung Recruitment Maneuver, Stepwise Lung Recruitment Maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ondokuz Mayıs University
Respiratory Distress of Newborn
Lung Ultrasound - Prospective Study
The goal of this clinical trial is to determine whether lung ultrasound can predict extubation success in neonates with respiratory distress. Participants will undergo a lung ultrasound pre- and post-extubation.
- Trial name
- NCT06140615
- Testing
- Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 71 people
- Sponsor
- University of Wisconsin, Madison
Atelectasis
Efficacy and Ventilatory Responses to VHI in Atelectasis Patients
The purpose of this study include (1) To investigate the efficacy of ventilator hyperinflation technique to re-expand lung atelectasis on patients with critical trauma who intubated and mechanical ventilation in the intensive…
- Trial name
- NCT02768350
- Testing
- Ventilator hyperinflation technique, Conventional treatment
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Khon Kaen University
Bariatric Surgery Candidate
Ultrasonograpahic Evaluation of Diaphragmatic Functions in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy
Major laparoscopic sleeve gastrectomy surgery requires steep Trendelenburg position with pneumoperitoneum for a long time leading to decrease pulmonary compliance and lung volumes due to cephalic displacement and decrease…
- Trial name
- NCT04130217
- Testing
- addition of positive end expiratory pressure in ventilated patients, addition of positive end expiratory pressure and recruitment maneuver in ventilated patients
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Coronary Artery Disease, Coronary Artery Bypass
Preload Dependency Evaluation With Stroke Volume Variation During Alveolar Recruitment Manoeuvres
The principal aim is to assess impact of alveolar recruitment manoeuvres (ARM) on stroke volume variation, evaluated by trans-oesophageal echocardiography (TEE).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass, Hypovolemia, Anesthesia, General
- Trial name
- PreDeARM (NCT02678559)
- Testing
- tee measurement, flotrac measurement, clearsight measurement
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atelectasis, Perioperative Oxygenation
Individualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia Surgery
During laparoscopic surgery under general anesthesia, lung function can be affected by increased abdominal pressure and patient positioning.
- Conditions
- Atelectasis, Perioperative Oxygenation, Laparoscopic Inguinal Hernia Repair, Mechanical Ventilation
- Trial name
- NCT07775573
- Testing
- Standard PEEP Ventilation, Individualized PEEP Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Postoperative Atelectasis
Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound
Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical…
- Trial name
- LUS-ATELEC (NCT07320092)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Atelectasis, Postoperative
Lung Recruitment in Laparoscpic Surgery
The goal of this clinical trial study is to assess the effectiveness of different methods of lung recruitment maneuver on the incidence of atelectasis in adults undergoing laparoscopic cholecystectomy surgery using lung…
- Trial name
- NCT06221449
- Testing
- Positive end expiratory pressure
- Where
- Egypt
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Preterm Birth, Distress Respiratory Syndrome
Adverse Neonatal Outcomes With a Shortened Clinical Regimen of Dexamethasone.
Respiratory morbidity, including respiratory distress syndrome (RDS), is a serious complication of preterm birth and the leading cause of early neonatal mortality and disability.
- Trial name
- UNODEXA (NCT06569251)
- Testing
- Dexamethasone 12 mg QD, Dexamethasone 6 mg BID
- Where
- Honduras
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Postoperative Pulmonary Atelectasis, Morbid Obesity
Perioperative Diaphragmatic Ultrasound as Predictive Index of Atelectasis in Bariatric Surgery
In this study the Authors assume that peri-operative changes in DIA are predictive of postoperative atelectasis, thus providing a clinically useful tool to stratify the need for high-intensity monitoring, including admission to…
- Trial name
- ECODIA (NCT04701541)
- Testing
- Diaphragmatic Ultrasound
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Complication of Surgical Procedure, Acute Respiratory Failure, Adult
Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric…
- Conditions
- Complication of Surgical Procedure, Acute Respiratory Failure, Adult, Postoperative Respiratory Complications, Pulmonary Failure
- Trial name
- PERISCOPE (NCT01346709)
- Where
- 63 sites in Albania, Belgium and 19 more
- Volunteers
- 5,450 people
- Sponsor
- European Society of Anaesthesiology
Respiratory Distress Syndrome (Neonatal), Surfactant Deficiency Syndrome Neonatal
Video vs. Direct Laryngoscopy for Less Invasive Surfactant Administration
Many preterm babies born between 22-28+6 weeks' estimated gestational age (EGA) need surfactant, a medicine that helps the lungs.
- Trial name
- VID LISA (NCT07426016)
- Testing
- Video Laryngoscopy, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas Southwestern Medical Center
Bronchoscopy, Atelectasis
Pulmonary Ventilation After Fiberoptic Bronchoscopy Using EIT
Background: Fiber bronchoscopy is a routine operation in intensive care unit (ICU), but it may cause local collapse of the lung.
- Conditions
- Bronchoscopy, Atelectasis, Mechanical Ventilation
- Trial name
- NCT05875662
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Lung Collapse, Lung Diseases
The Accuracy of Pediatric Air Test as a Non-invasive Atelectasis Diagnostic Tool
HYPOTHESIS: During anesthetic pre-oxygenation with high FiO2, pulmonary atelectasis occur, especially in patients < 6 years old, where FRC and pulmonary closing volume may overlap.
- Conditions
- Lung Collapse, Lung Diseases, Atelectasis, Atelectasis Without Respiratory Distress Syndrome
- Trial name
- NCT04506203
- Testing
- Air test
- Where
- 3 sites in Argentina, Spain
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Atelectases, Postoperative Pulmonary, Prone Position
ORI-Guided FiO₂ Titration in Prone Spine Surgery: Impact on Postoperative Atelectasis Assessed by Lung Ultrasound
Atelectasis is a frequent pulmonary complication after general anesthesia, often triggered by preoxygenation and intraoperative hyperoxia.
- Conditions
- Atelectases, Postoperative Pulmonary, Prone Position, Spine Surgery, Lung Ultrasound
- Trial name
- NCT07375173
- Testing
- Titrated Oxygen, Fixed oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital