Clinical trials: Atherosclerosis Cerebral
Death, Carotid Artery Disease
NOR-SYS: The Norwegian Stroke in the Young Study
NOR-SYS is a clinical research program about young ischemic stroke patients from 15 to 60 years. Patients, partners and the couple´s adult children who are at least 18 years old, are all invited to ultrasound examinations due to…
- Conditions
- Death, Carotid Artery Disease, Cardiovascular Disease, Peripheral Artery Disease
- Trial name
- NOR-SYS (NCT01597453)
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Atherosclerosis, Carotid Stenosis
Classification of Carotid Plaque With Computed Tomography With Fast kVp (Kilovolt Peak)-Switching Technique
Classification of carotid plaque vessel wall changes in carotid stenosis accordingly to AHA classification (American Heart Association)- comparison between histology and CT.
- Trial name
- NCT02436967
- Testing
- Carotid endarterectomy in clinical healthcare.
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- Karolinska Institutet
Familial Hypercholesterolemia, Hypercholesterolemia
Evaluation of a Digiphysical Screening Method to Identify and Diagnose Familial Hypercholesterolemia
Longitudinal and observational registry-based cohort study of individuals participating in the national digiphysical screening program for Familial Hypercholesterolemia.
- Trial name
- DigiLipids (NCT04929457)
- Where
- Sweden
- Volunteers
- 30,000 people
- Sponsor
- Karolinska Institutet
Chronic Venous Insufficiency, Peripheral Arterial Disease
Outpatient Office Based Endovascular Procedures
The results of this study will serve as a starting point for future trials concentrating on the effectiveness and clinical outcomes of the procedures performed in an office based angiosuite.
- Conditions
- Chronic Venous Insufficiency, Peripheral Arterial Disease, Dialysis Access Malfunction, Arterio-venous Fistula
- Trial name
- NCT04054440
- Where
- United States
- Volunteers
- 26,000 people
- Sponsor
- Methodist Health System
Stroke, Acute, Stroke, Ischemic
Carotid Artery Stenting During Endovascular Treatment of Acute Stroke
Rationale: Approximately 20% of the patients with acute ischemic stroke due to an intracranial large vessel occlusion (LVO) has a high-grade stenosis in the ipsilateral cervical carotid artery.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Carotid Stenosis, Carotid Atherosclerosis
- Trial name
- CASES (NCT06511089)
- Testing
- carotid artery stenting during EVT, no carotid artery stenting during EVT
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- University Medical Center Groningen
Carotid Atherosclerosis, Carotid Artery Stenting
Long-term Follow-up NIRS-IVUS Imaging of Pre-existing Carotid Stents
The 'Long-term Follow-up Near-infrared Spectroscopy and Intravascular Ultrasound Imaging of Internal Carotid Artery Stenosis Treated With Stenting' trial is an academic research project.
- Conditions
- Carotid Atherosclerosis, Carotid Artery Stenting, Atherosclerotic Plaque, Near Infrared Spectroscopy
- Trial name
- NCT03141580
- Testing
- Near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS)
- Where
- Czechia
- Volunteers
- 52 people
- Sponsor
- University Hospital, Motol
Atherosclerosis, Cardiovascular Diseases
Prevalence & Progression of Subclinical Atherosclerosis
To evaluate subclinical atherosclerotic disease in menopausal women.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Arteriosclerosis, Carotid Artery Diseases
- Trial name
- NCT00006503
- Sponsor
- Rush University Medical Center
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, 2nd Wave
The CLIMATE-II Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-II (NCT06407154)
- Where
- Germany
- Volunteers
- 578 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD)
VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN)
The goal of this study is to understand and compare an alternative model of care in comparison to the usual model of care in include male and female participants ≥18 years of age with a history of ASCVD (hear and blood vessels…
- Conditions
- Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD), Cerebrovascular Disease, Peripheral Arterial Disease (PAD)
- Trial name
- v-ASCERTAIN (NCT05834673)
- Testing
- SMS messages, Telephone-based support calls, GP Education
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Monash University
Intracranial Atherosclerosis, Atherosclerotic Plaque
Extra Alirocumab in Addition to Statin Therapy in Asymptomatic Intracranial Atherosclerotic Stenosis (EAST-aICAS)
The primary goal of the trial is to investigate whether the lipid lowering strategy using Alirocumab plus statin could cause more changes from baseline in intracranial atherosclerotic plaque and hemodynamic features during 6…
- Conditions
- Intracranial Atherosclerosis, Atherosclerotic Plaque, Stenosis
- Trial name
- EAST-aICAS (NCT06080256)
- Testing
- Alirocumab, Atorvastatin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Hyperlipidemias, Atherosclerosis
Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
A cholesterol/lipid profile screening project of high risk patients with hyperlipidaemia (secondary prevention) who already receive cholesterol-lowering therapy.
- Conditions
- Hyperlipidemias, Atherosclerosis, Coronary Heart Disease, Carotid Stenosis
- Trial name
- NCT00536965
- Where
- Austria
- Volunteers
- 951 people
- Sponsor
- AstraZeneca
Carotid Atherosclerosis
Artificial Intelligence Based Comprehensive Assessment System of Carotid Plaque Stability
Stroke is a common clinical disease with high disability and mortality, which seriously threatens human life and health.Carotid atherosclerotic plaque rupture is an important pathogenic basis of ischemic stroke, so judging the…
- Trial name
- NCT04544657
- Testing
- no intervention
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Myocardial Infarction, Ischemic Stroke
Alpha-linolenic Acid and the Risk of ASCVD
Background: The plant-derived omega-3 fatty acid alpha-linolenic acid (ALA, 18:3-n-3) may reduce the risk of atherosclerotic cardiovascular disease, including incident myocardial infarction, ischemic stroke and peripheral artery…
- Conditions
- Acute Myocardial Infarction, Ischemic Stroke, Peripheral Artery Disease
- Trial name
- NCT03258983
- Testing
- Alpha-linolenic acid
- Volunteers
- 57,053 people
- Sponsor
- Aalborg University Hospital
Coexistence of Cerebral and Coronary Atherosclerosis, Acute Ischemic Cerebrovascular Disease
Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry
Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is a single-center observational registry of patients hospitalized for acute ischemic cerebrovascular…
- Trial name
- CoCCA (NCT03788512)
- Testing
- observational only- no intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Artery Plaque
TMAO and Atherosclerosis in HIV
In the present study, the investigators sought to prospectively examine the associations of plasma levels of TMAO (trimethylamine oxide), choline, betaine, dimethylglycine, and sarcosine with risk of incident carotid artery…
- Trial name
- NCT03416257
- Testing
- No intervention
- Volunteers
- 737 people
- Sponsor
- Albert Einstein College of Medicine
Carotid Atherosclerosis, Peripheral Arterial Disease
Non-invasive Computer-Aided Phenotyping of Vasculopathy
The investigators use MRI and/or CT to evaluate the extent, as well as, the structure, composition, and functional aspects of atherosclerotic plaques in human carotid and femoral arteries in patients scheduled to undergo an…
- Trial name
- Q-CAMP (NCT02143102)
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- Elucid Bioimaging Inc.
Atherosclerosis, Atherosclerotic Plaque
Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque
This will be a pilot study of 9 patients undergoing standard-of-care clinically indicated carotid endarterectomy. The nine patients will receive an injection of Indocyanine green (ICG) at a dose of 0.25 mg/kg (maximum 25 mg) as…
- Conditions
- Atherosclerosis, Atherosclerotic Plaque, Carotid Stenosis
- Trial name
- BRIGHT-CEA (NCT01873716)
- Testing
- Indocyanine green
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Massachusetts General Hospital
Carotid Atherosclerosis
Shear Wave Elastography for Carotid Atherosclerotic Plaques
The goal of this prospective diagnostic accuracy cohort study is to compare the accuracy of carotid atherosclerotic plaques stiffness assessed by shear wave elastography (SWE) with greyscale median values (GSM), magnetic…
- Trial name
- NCT06214429
- Testing
- Vascular Ultrasound, Shear Wave Elastography, Greyscale Median
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Coronary Disease
The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease
Prior work (Chris, M. et al, Clinical Science 2005; 109, 55-60) has demonstrated that drinking a cup of coffee (80-100 mg of caffeine) an hour before endothelium-dependent FMD (flow-mediated dilatation) of the brachial artery…
- Trial name
- NCT00564824
- Testing
- Caffeine
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Carotid Artery Disease, Atherosclerosis
Telerobotic Ultrasound for Carotid Imaging - Feasibility Study
In this proposal, the investigators will demonstrate the feasibility and noninferiority of telerobotic ultrasonography as compared to traditional manual acquisition in performing a limited carotid Duplex examination and in…
- Conditions
- Carotid Artery Disease, Atherosclerosis, Atheromatous Plaques, Arteriosclerosis
- Trial name
- NCT05654935
- Testing
- Ultrasound for Carotid Arteries, Telerobotic Ultrasound for Carotid Arteries
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center