Clinical trials: Atrial Fibrillation Catheter Ablation
Atrial Fibrillation
Dual Epicardial Endocardial Persistent Atrial Fibrillation(AF) Study (Staged DEEP)
The purpose of this study is to assess the safety and technical feasibility of treating subjects with Persistent Atrial Fibrillation or Longstanding Persistent Atrial Fibrillation in a minimally invasive thoracoscopic ablation…
- Trial name
- Staged DEEP (NCT01661205)
- Testing
- Ablation procedure staged catheter ablation
- Where
- 6 sites in United States, Belgium and 1 more
- Volunteers
- 30 people
- Sponsor
- AtriCure, Inc.
Atrial Fibrillation (AF)
Non-invasive Mapping-Guided Atrial Fibrillation Ablation
The goal of this pilot study is to test if noninvasive global mapping can guide catheter ablation defining personalized targets and improve the therapy of atrial fibrillation. It will also test the safety of such an approach.
- Trial name
- ELISA-AF (NCT07358611)
- Testing
- Non-invasive mapping-guided ablation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Clinic of Barcelona
Paroxysmal Atrial Fibrillation
Pilot Study Evaluating the Toray Satake Balloon Thermal Ablation System for Treatment of Paroxysmal Atrial Fibrillation
The purpose of this study is to collect preliminary safety and effectiveness data evaluating the Toray Satake Balloon Thermal Ablation System (TSB)to treat subjects with symptomatic paroxysmal atrial fibrillation that is…
- Trial name
- NCT01997736
- Testing
- Ablation
- Where
- 4 sites in United States
- Volunteers
- 41 people
- Sponsor
- Toray Industries (America), Inc.
Atrial Fibrillation, Heart Failure
Catheter Ablation Versus Medical Treatment of AF in Heart Failure
Heart failure and atrial fibrillation (AF) often coexist, and each increases the morbidity and mortality associated with the other.
- Trial name
- CAMTAF (NCT01411371)
- Testing
- Catheter ablation of persistent atrial fibrillation, Medical treatment alone
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Barts & The London NHS Trust
Heart Failure, Atrial Fibrillation
Catheter Ablation for Atrial Fibrillation in patientS With End-sTage Heart Failure and Eligibility for Heart Transplantation
CASTLE-HTx will determine if AF ablation has beneficial effects on mortality in patients with end stage HF who are eligible for HTx
- Trial name
- CASTLE-HTx (NCT04649801)
- Testing
- Atrial fibrillation ablation
- Where
- Germany
- Volunteers
- 194 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Paroxysmal Atrial Fibrillation
Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation
To obtain data for the Rhythmia™ Mapping System in conjunction with Boston Scientific Open-Irrigated (OI) Catheters for ablation of Paroxysmal Atrial Fibrillation (PAF) according to current international and local guidelines.
- Trial name
- INTERRUPT AF (NCT03729830)
- Testing
- Boston Scientific Open Irrigated Ablation Catheters
- Where
- 26 sites in United States, Germany and 4 more
- Volunteers
- 415 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation
Efficacy, Safety and Efficiency Study of CARTO® 3 System Guided THERMOCOOL® Catheter Ablation Versus Fluoroscopy Guided Ablation With the Pulmonary Vein Ablation Catheter® (PVAC®)
The purpose of this study is to compare the efficacy, safety and efficiency of CARTO® 3 system guided THERMOCOOL® catheter ablation and fluoroscopy guided Pulmonary Vein Ablation Catheter® (PVAC®) guided ablation for the…
- Trial name
- CLARITY-AF (NCT01116557)
- Testing
- Radiofrequency Ablation procedure
- Volunteers
- 79 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation (AF), Coronary Artery Disease
OPTIA-AF Trial: Rhythm-Guided Antithrombotic Strategy After AF Ablation
The OPTIA-AF trial is a prospective, multicenter randomized controlled trial designed to evaluate a rhythm-guided antithrombotic strategy in patients with atrial fibrillation (AF) who maintain durable sinus rhythm after catheter…
- Conditions
- Atrial Fibrillation (AF), Coronary Artery Disease, Drug-eluting Stent
- Trial name
- OPTIA-AF (NCT07496281)
- Testing
- Oral anticoagulation, Single antiplatelet therapy
- Where
- South Korea
- Volunteers
- 2 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Atrial Fibrillation, Subclinical Hyperthyroidism
Is a Low Thyreotropin Level Predictive of Recurrent Arrhythmia After Catheter Ablative Surgery?
Overt hyperthyroidism (so-called "goiter" in lay language) is a hormonal disturbance that is known to increase the risk of atrial fibrillation (a common heart arrhythmia with potentially severe consequences) in some patients.
- Trial name
- TABLAS (NCT01789541)
- Where
- 2 sites in Sweden
- Volunteers
- 327 people
- Sponsor
- Karolinska Institutet
Atrial Fibrillation, Atrial Fibrillation, Persistent
Electrical Cardioversion As a Predictor in Postoperative Preservation of Sinus Rhythm
The aim of this study is to evaluate benefits of electric cardioversion in the early and long-term postoperative period in patients after radiofrequency catheter isolation of pulmonary veins.
- Trial name
- NCT06654401
- Testing
- Transthoracic echocardiography, 24-hour ECG Monitor, Electroanatomic mapping
- Where
- Russia
- Volunteers
- 125 people
- Sponsor
- Saint Petersburg State University, Russia
Atrial Fibrillation, Persistent, Heart Failure
Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure
The goal of this clinical trial is to evaluate two treatment strategies in patients with chronic atrial fibrillation and heart failure, who are eligible for atrial fibrillation ablation.
- Trial name
- ABACUS (NCT06207383)
- Testing
- Conduction system pacing, Atrioventricular nodal ablation, Atrial fibrillation ablation
- Where
- 18 sites in Austria, Belgium and 12 more
- Volunteers
- 220 people
- Sponsor
- University Hospital, Geneva
Atrial Fibrillation
Safety and Effectiveness of STSF Catheter Evaluated for Treating Symptomatic Persistent Atrial Fibrillation (PsAF)
This is a prospective, multicenter, non-randomized clinical evaluation utilizing the THERMOCOOL SMARTTOUCH® SF catheter compared to a predetermined performance goal.
- Trial name
- PRECEPT (NCT02817776)
- Testing
- THERMOCOOL SMARTTOUCH® SF catheter
- Volunteers
- 381 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation
Atrial Fibrillation After Catheter Versus Thoracoscopic Ablation Using Patient Activated Implantable Loop Recorders: The ACTUAL Study
Atrial fibrillation (AF) is a common but often distressing condition. It can be treated with medications, but these are not always effective or tolerated.
- Trial name
- ACTUAL (NCT01503268)
- Testing
- Implantation of implantable loop recorder, Percutaneous ablation of atrial fibrillation, Surgical ablation of atrial fibrillation
- Where
- 2 sites in United Kingdom
- Sponsor
- East Sussex Healthcare NHS Trust
Atrial Fibrillation
Edoxaban Treatment Versus Vitamin K Antagonist (VKA) in Patients With Atrial Fibrillation (AF) Undergoing Catheter Ablation
There are insufficient data on the safety and efficacy of edoxaban therapy in subjects with AF following catheter ablation. This phase 3b study is designed to evaluate the safety and to explore the efficacy of an edoxaban-based…
- Trial name
- ELIMINATE-AF (NCT02942576)
- Testing
- Edoxaban, VKA-Based Regimen
- Where
- 75 sites in Belgium, Canada and 9 more
- Volunteers
- 632 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Atrial Fibrillation
Atrial Fibrillation Ablation: Radiofrequency or Cryoablation?
The study aims to compare 3 techniques routinely used for paroxysmal atrial fibrillation ablation: radiofrequency catheter ablation without contact-force, radiofrequency catheter ablation with contact-force and cryoablation.
- Trial name
- ARCFA (NCT03774550)
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Atrial Fibrillation (AF)
Utility of Analyzing Atrial Signal Electrograms in Patients with Atrial Fibrillation Using Next-Generation Ensite X Software: a Prospective Study
A single-center clinical trial on the analysis of intracardiac atrial electrogram mapping before and after ablation with the HD Grid Mapping Catheter and Ensite X Software, as a prospective study.
- Trial name
- NCT06632925
- Testing
- Catheter ablation
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Persistent Atrial Fibrillation
Benefit of CFAE Ablation
The optimal strategy for catheter ablation of persistent atrial fibrillation is not clearly defined. This study investigates if Complex Fractionated Atrial Electrogram (CFAE) ablation in addition to pulmonary vein isolation and…
- Trial name
- BOCA (NCT01711047)
- Testing
- Radiofrequency catheter Ablation
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Oxford University Hospitals NHS Trust
Atrial Fibrillation
Manual vs Amigo SmartTouch Atrial Fibrillation Study
Atrial fibrillation is a common form of heart rhythm disturbance that for some patients is treated by catheter ablation (making an ablation lesion or burn inside the heart using a fine wire (catheter)).
- Trial name
- MAST-AF (NCT01583855)
- Testing
- Catheter ablation for atrial fibrillation, manual, Ablation using Amigo remote catheter system
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Leicester
Atrial Fibrillation (AF), Atrial Flutter
Electrophysiological Registry Duesseldorf
This registry at University Hospital Düsseldorf collects retrospective and prospective (from 2019 onward) data on patients undergoing electrophysiological studies (EPS), catheter ablation, and electrical cardioversion.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Supraventricular Tachycardias, Ventricular Tachycardia (VT)
- Trial name
- NCT07196176
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Atrial Fibrillation
Clinical Benefits of Additional Complex Fractionated Atrial Electrogram Targeted Catheter Ablation for Longstanding Persistent Atrial Fibrillation
1. Purpose of the study 1) To compare clinical outcome, procedure time, complication rate of persistent atrial fibrillation patients between conventional additional linear ablation and additional complex fractionated atrial…
- Trial name
- NCT02175043
- Testing
- atrial electrogram and liner ablation
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University