Clinical trials: Atrial Tachyarrhythmia
Tachyarrhythmia, Atrial Flutter
MCG for Localization of Tachyarrhythmia's Origin
This is an exploratory research aiming to accurately identify the site of origin of tachyarrhythmia using Magnetocardiography (MCG), which will have guiding significance for early diagnosis, the formulation of treatment plans and…
- Conditions
- Tachyarrhythmia, Atrial Flutter, Paroxysmal Supraventricular Tachycardia, Atrial Tachycardia
- Trial name
- NCT06327425
- Testing
- Magnetocardiography
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Qilu Hospital of Shandong University
Atrial Fibrillation, Tachycardia
Management and Detection of Atrial Tachyarrhythmias in Patients Implanted With BIOTRONIK DX Systems
This is an observational registry study aiming to collect data on efficacy and safety of the single chamber Biotronik DX system with enhanced atrial diagnostics. The minimal follow-up period is 24 months.
- Conditions
- Atrial Fibrillation, Tachycardia, ICD Therapy, Thromboembolic Events
- Trial name
- MATRIX (NCT01774357)
- Where
- Germany
- Volunteers
- 2,054 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Fibrillation (AF), Atrial Fibrillation Ablation Procedure
Efficacy and Safety of a Voltage-Guided Stepwise Strategy for Pulmonary Vein Isolation
The goal of this clinical trial is to learn if a voltage-guided stepwise pulmonary vein isolation (PVI) strategy can achieve effective PVI while potentially reducing lesion delivery, compared with conventional circumferential…
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Ablation Procedure, Atrial Tachyarrhythmia Recurrence, Esophageal Thermal Injury
- Trial name
- VoS-PVI (NCT07354737)
- Testing
- Radiofrequency ablation catheter system
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Ajou University School of Medicine
Tachyarrhythmia, Atypical Atrial Flutter
Outcome of Induced Atypical Atrial Flutter
Background: Atypical atrial flutter (AAF) is an increasingly relevant clinical problem. Despite advancements in mapping and ablation techniques, the general management of these patients remain challenging especially when mapping…
- Conditions
- Tachyarrhythmia, Atypical Atrial Flutter, Induction of Arryhthmia, Clinical Outcome
- Trial name
- NCT06323499
- Testing
- Induction of atypical atrial flutter
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- University Hospital, Essen
Tachyarrhythmias, Syncope
Study of New Implantable Loop Recorder
The goal of this IDE clinical study is to evaluate the quality of the cardiac signal recordings obtained by the St. Jude Medical (SJM) Confirm Implantable Cardiac Monitor (device).
- Trial name
- NCT00746564
- Testing
- SJM Confirm
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- Abbott Medical Devices
Atrial Tachyarrhythmia, Atrial Fibrillation
The REACT-ICD Trial
Recent advancements with implantable cardiac device technology include extensive diagnostic and therapeutic algorithms for prevention as well as termination of atrial tachyarrhythmias (ATA).
- Trial name
- REACT-ICD (NCT02439424)
- Testing
- Reactive ATP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Hartford Hospital
Tachyarrhythmia
APART: Prevention and Automatic Therapy of Atrial Arrhythmias in Patients With Paroxysmal Supraventricular Tachycardias
The goal of APART is the assessment of the therapeutic and preventive stimulation algorithms of the Medtronic AT500 and following devices in patients with atrial tachyarrhythmias and an indication for cardiac pacing according to…
- Trial name
- NCT00170274
- Testing
- Activation of preventive and therapeutic algorithms for treatment of AF, AF Prevention and Therapy Algorithms On
- Where
- 6 sites in Germany
- Volunteers
- 156 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Cardiovascular Diseases
Management of Device Detected AT and Impact of Device Treatment Algorithms on Atrial Fibrillation
The MANDATE-AF study was designed to address evidence needs in India for device-based management of AF using AT/AF (Atrial Tachycardia/Atrial fibrillation) diagnostic features and therapies such as Reactive Atrial anti…
- Trial name
- MANDATE-AF (NCT04172883)
- Testing
- Treatment arm
- Where
- 11 sites in India
- Volunteers
- 79 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Ventricular Tachycardia, Ventricular Fibrillation
The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock
The RAPTURE Study will determine whether dual chamber defibrillators with atrial prevention and termination therapies, minimized ventricular pacing, and remote monitoring will reduce the rate of inappropriate shocks and improve…
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Atrial Fibrillation, Supraventricular Tachycardia
- Trial name
- RAPTURE (NCT00787800)
- Testing
- Dual Chamber ICD, Single Chamber ICD
- Where
- 4 sites in United States, Israel
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation, Alcohol
The HOLIDAY (HOw ALcohol InDuces Atrial TachYarrhythmias) Study
Atrial fibrillation (AF) is the most common sustained arrhythmia in the United States and it has been associated with ethanol use.
- Trial name
- HOLIDAY (NCT01996943)
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Atrial Fibrillation, Atrial Tachyarrhythmia
The Dynamics of Human Atrial Fibrillation
The study is conducted in patients with atrial fibrillation undergoing clinically prescribed ablation. The study hypothesis is that ablation at specific sites that are identified to 'drive' the atrial fibrillation may improve the…
- Trial name
- NCT01008722
- Where
- 2 sites in United States
- Volunteers
- 98 people
- Sponsor
- University of California, San Diego
Atrial Fibrillation
Non-Invasive Median Nerve Stimulation to Attenuate Atrial Tachyarrhythmias After Catheter Ablation for Atrial Fibrillation
Determine the role of vagal/median nerve stimulation using the CardiaCare RR2 home care wearable neuromodulation system on suppressing atrial arrhythmias and related symptoms in patients who have undergone AF ablation.
- Trial name
- NEUROPULSE (NCT06748157)
- Testing
- CardiaCare RR2
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Tachyarrhythmia, Atrial Fibrillation (AF)
Master Study of the BIOMONITOR III and Incision and Insertion Tool (FIT OneStep)
This study is a post-market clinical follow-up (PMCF) study to identify and evaluate residual risks associated with the use of the BIOMONITOR III and BIOMONITOR IIIm that are discovered or remain even after risk analysis, risk…
- Conditions
- Tachyarrhythmia, Atrial Fibrillation (AF), Syncope, Cryptogenic Stroke
- Trial name
- NCT04025710
- Testing
- BIOMONITOR III and BIOMONITOR IIIm
- Where
- 27 sites in Australia, Austria and 4 more
- Volunteers
- 167 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Fibrillation
Evaluation of Conventional Ablation With or Without Focal Impulse and Rotor Modulation to Eliminate Human AF
This prospective randomized study will assess the safety and efficacy of FIRM-guided ablation (FIRM+PVI) compared to pulmonary vein isolation (PVI) without FIRM, for the treatment of symptomatic atrial fibrillation.
- Trial name
- RECONFIRM (NCT02456233)
- Testing
- Conventional AF Ablation with PVI, FIRM-guided ablation plus PVI
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- Stanford University
Shock
Vasoactive Drugs in Intensive Care Unit
The investigators hypothesis is that for ICU patients with shock, the use of the vasoactive drugs phenylephrine and vasopressin will reduce tachydysrhythmias when compared to norepinephrine and epinephrine.
- Trial name
- NCT02118467
- Testing
- Norepinephrine, Epinephrine, Phenylephrine
- Where
- United States
- Volunteers
- 836 people
- Sponsor
- University of Chicago
Atrial Fibrillation
RATE Registry - Registry of Atrial Tachyarrhythmia/Atrial Fibrillation (AT/AF) Episodes in the Cardiac Rhythm Management (CRM) Device Population
The purpose of this registry is to produce a prospective, outcome-oriented registry to document the prevalence of AT/AF in the CRM population by using the Advanced AT/AF Diagnostics in select SJM devices.
- Trial name
- RATE (NCT00837798)
- Testing
- CRM Device
- Where
- United States
- Volunteers
- 5,379 people
- Sponsor
- Abbott Medical Devices
Heart Failure
MODULA Modul 5 BEAT-HF
Detektion and Registration of Atrial Tachyarrhythmias at Patients with Heart Failure; What proportion of patients with CRT-therapy are affected at least temporarily by Atrial Arrhythmia?
- Trial name
- NCT00273091
- Testing
- ICD with CRT therapy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation
Substrate Versus Trigger Ablation for Paroxysmal Atrial Fibrillation
This is a prospective randomized study to assess the safety and efficacy of FIRM (Focal Impulse and Rotor Modulation)-guided ablation for the treatment of symptomatic atrial fibrillation (AF).
- Trial name
- SUBSTRATE (NCT02169037)
- Testing
- FIRM Ablation, Conventional AF ablation with PVI
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Atrial Fibrillation, Atrial Flutter
Impact of Catheter Ablation on ABC Risk Scores
The aim of this prospective, monocentric, non-randomized trial is to investigate the impact of catheter ablation of atrial tachyarrhythmias on the ABC-stroke and ABC-bleeding risk scores.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Stroke, Bleeding
- Trial name
- CathonABC (NCT05635864)
- Testing
- Catheter ablation
- Where
- Germany
- Volunteers
- 167 people
- Sponsor
- Hannover Medical School
Ventricular Tachycardia, Coronary Artery Disease
Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia
This study aims to compare antiarrhythmic drug therapy with catheter ablation using the SmartTOUCH catheter (Biosense Webster Inc.) as treatment for patients with ventricular tachycardia and coronary artery disease
- Trial name
- VeTAMed (NCT01798277)
- Testing
- Catheter Ablation, Medical therapy (sotalol or amiodarone)
- Sponsor
- Newmarket Electrophysiology Research Group Inc