Clinical trials: Atrioventricular Nodal Disease
Cardiac Arrhythmia, Atrial Fibrillation
Vektor vMap™ Clinical Validation Study
This is a retrospective, multi center clinical study collecting existing, de-identified subject data from medical records to be analyzed using an independent core laboratory to validate performance of a computational ECG mapping…
- Conditions
- Cardiac Arrhythmia, Atrial Fibrillation, Ventricular Arrythmia, Premature Ventricular Complexes Multiple
- Trial name
- NCT04559061
- Testing
- Cardiac ablation procedure
- Where
- 4 sites in United States
- Volunteers
- 225 people
- Sponsor
- Vektor Medical
Paroxysmal Supraventricular Tachycardia
Efficacy and Safety of Etripamil for the Termination of Spontaneous Paroxysmal Supraventricular Tachycardia (PSVT).
This was a three-part, multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of etripamil nasal spray (NS) self-administered by participants who experienced an episode of paroxysmal…
- Trial name
- NODE-301 (NCT03464019)
- Testing
- Etripamil, Etripamil Test Dose
- Where
- 161 sites in United States, Belgium and 7 more
- Volunteers
- 1,097 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Atrioventricular Nodal Reentry Tachycardia, Radiofrequency Ablation
Magnetically Navigated vs. Manually Guided Radiofrequency in Atrioventricular-node-reentry-tachycardia
The MAGMA-AVNRT study compares two different methods of handling the ablation catheters for av-node-reentry-tachycardia with regard to x-ray dose, safety and success: manually guided vs magnetically navigated RF-catheter.
- Trial name
- MAGMA-AVNRT (NCT00875914)
- Testing
- RF-ablation
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Deutsches Herzzentrum Muenchen
AtrioVentricular Nodal Reentrant Tachycardia, Supraventricular Tachycardia
Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia
ICY-AVNRT (Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia) is a prospective multi-center, nonrandomized, single arm, controlled, unblinded, investigational clinical study.
- Conditions
- AtrioVentricular Nodal Reentrant Tachycardia, Supraventricular Tachycardia, Heart Disease
- Trial name
- NCT01426425
- Testing
- Freezor Xtra Cryoablation Catheter
- Where
- 34 sites in United States, Canada
- Volunteers
- 572 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Atrioventricular Nodal Reentry Tachycardia
European Multicenter Study Radiofrequency (RF) Versus Cryo in Atrioventricular Nodal Reentry Tachycardia (AVNRT)
In this randomized study, two energy sources for the ablation of AV nodal reentry tachycardia are compared: The standard technique of radiofrequency energy delivery is compared with the new approach of cryo-energy application.
- Trial name
- NCT00196222
- Testing
- RF-ablation, cryo ablation
- Where
- 10 sites in Germany
- Volunteers
- 509 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Atrial Fibrillation (AF)
Atrioventricular Nodal Ablation Versus Pulmonary Vein Isolation - Patient Centred Decisions
The goal of this clinical trial is to compare two procedural approaches to managing atrial fibrillation. The main questions it aims to answer are: Is AF ablation or pacemaker implant and AV nodal ablation a more effective…
- Trial name
- AVENUE PACE (NCT07059208)
- Testing
- Atrioventricular nodal ablation, Pulmonary vein isolation
- Volunteers
- 172 people
- Sponsor
- Sunshine Coast Hospital and Health Service
Supraventricular Tachycardia (SVT), Atrioventricular Nodal Re Entrant Tachycardia
Adenosine vs. Diltiazem
In this Emergency Department (ED)-based study, the investigators evaluated a standardized modified Valsalva maneuver (MVM) as first-line therapy and compared intravenous (IV) adenosine with IV diltiazem among patients with…
- Trial name
- AVNRTstdy (NCT07456423)
- Testing
- Adenosine intravenous, Diltiazem intravenous
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Haseki Training and Research Hospital
Sinus Bradycardia, Atrioventricular Block
Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart
Heart transplants save the lives of nearly 500 children in heart failure per year. Columbia is one of the largest pediatric heart transplant centers in the world, averaging 25 transplants per year, and providing ongoing care to…
- Trial name
- NCT02462941
- Testing
- Adenosine, Cardiac catheterization
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Columbia University
Atrial Fibrillation
Microfidelity (MIFI) Ablation Technology Versus Standard Ablation Catheter for Atrioventricular Nodal Ablation
The aim of our study is to investigate the comparative efficacy of high fidelity multi electrode ablation catheters vs the standard bipolar configuration in success of AV nodal ablation This study will provide insights on the use…
- Trial name
- NCT03114124
- Testing
- MIFI Catheter, Standard Ablation Catheter
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Atrioventricular Nodal Re Entrant Tachycardia
Atrioventricular Nodal Reentrant Tachycardia Ablation With Irrigated Catheter and Three-dimensional Electroanatomic Mapping
The WATER ATTAC study aims at multicentric, longitudinal, perspective evaluation of safety and efficacy of atrioventricular nodal reentrant tachycardia (AVNRT) performed combining irrigated ablation catheter and three-dimensional…
- Trial name
- WATER ATTAC (NCT05109273)
- Testing
- Transcatheter ablation
- Where
- Italy
- Volunteers
- 289 people
- Sponsor
- University Hospital of Ferrara
Tachycardia, Atrioventricular Nodal Reentry, Re-entrant Atrioventricular Tachycardia
Patients' Perspective on Radiofrequency Catheter Ablation of AVRT and AVNRT
Atrioventricular nodal reciprocating tachycardia (AVNRT) and atrioventricular reciprocating tachycardia (AVRT) are two similar supraventricular re-entry tachycardias (SVT) emerging in relatively young age in patients without…
- Trial name
- PPRA (NCT01594814)
- Testing
- RFA
- Where
- Poland
- Volunteers
- 82 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Supraventricular Tachycardia, Atrioventricular Nodal Re Entrant Tachycardia
High-density Activation Mapping of the Slow Pathwayto Guide Catheter Ablation in Patients With Typical Atrioventricular Nodal Reentrant Tachycardia
Atrioventricular nodal reentrant tachycardia (AVNRT) is the most common supraventricular tachycardia inducible during an electrophysiological study.
- Trial name
- NCT05531903
- Testing
- Description of Slow pathway signals to facilitate ablation
- Where
- Spain
- Volunteers
- 119 people
- Sponsor
- Parc de Salut Mar
Tachycardia, Atrioventricular Nodal Reentry
CryoCath Freezor CryoAblation Catheter System (CRYOFACTS)
The purpose of this post approval study of heart block is to gather additional information regarding how often patients develop heart block (atrioventricular block) after having standard ablation procedure using cryotherapy with…
- Trial name
- PS-010 (NCT00621621)
- Testing
- Freezor® Cardiac Cryoablation Catheter CryoConsole System
- Where
- 4 sites in United States
- Volunteers
- 105 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Tachycardia, Atrioventricular Nodal Reentry
Typical and Atypical AVNRT High-resolution Mapping
This study is aimed at : 1. Identifying the exact location of the circuit of typical and atypical AVNRT by applying high-resolution electroanatomic mapping. 2.
- Trial name
- AVNRTmap (NCT04764123)
- Testing
- AVNRT mapping
- Volunteers
- 30 people
- Sponsor
- Cardiovascular Research Society, Greece
Atrioventricular Reentrant Tachycardia
Non-invasive Left-sided Cervical Vagus Nerve Stimulation for Atrioventricular Reentrant Tachycardia
The goal of this Interventional clinical trials in atrioventricular reentrant tachycardia patients. The main question it aims to answer whether non-invasive vagus nerve stimulation could be effective in restoring rhythm.
- Trial name
- NCT06219343
- Testing
- Non-invasive vagus nerve stimulation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Jingye Tai
Atrioventricular Nodal Disease
Left Bundle Branch Pacing Versus Conventional Pacing in Atrioventricular Block
Recently, the concept of physiological pacing has emerged in the clinical practice, in an attempt to prevent the deteriorating effects of right ventricular pacing in the long-term.
- Trial name
- NCT05129098
- Testing
- Left bundle branch pacing lead (Select Secure 3830 lead), Right ventricular active fixation lead
- Where
- Greece
- Volunteers
- 38 people
- Sponsor
- University Hospital of Patras
Arrhythmias, Cardiac, Atrial Fibrillation
enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening
This research will investigate the PPG signal morphology related to physiological and non- physiological changes in arrhythmia-related heart rate as well as the performance of the PPG-based features previously developed within…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter, Atrioventricular Block
- Trial name
- enHEART (NCT04884100)
- Testing
- Validating and improving PPG-based algorithms
- Where
- Switzerland
- Volunteers
- 95 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Tachycardia, Atrioventricular Nodal Reentry
AV Nodal Reentrant Tachycardia Study
The purpose of this study is to determine/identify what mechanisms/factors are involved with regard to AV nodal reentrant tachycardia.
- Trial name
- AVNRT (NCT00618683)
- Testing
- Cardiac Invasive Electrophysiological Study
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Oklahoma
Supraventricular Tachycardia
Treatment Study of AV Node Reentry Tachycardia
Compare the effectiveness and safety of two techniques for modification of slow AV nodal pathway conduction underlying AVNRT: 1) New Ablation Technique, low voltage and wave front collision mapping vs.
- Trial name
- AVNRT (NCT04232371)
- Testing
- New Ablation Technique, Standard Ablation Technique
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Jeffrey Moak
Supraventricular Tachycardia, Atrioventricular Nodal Reentrant Tachycardia
Comparative Study Between Cryoablation and Radiofrequency Ablation in the Treatment of Supraventricular Tachycardia
The purpose of this study is to compare the safety and effectiveness of cryoablation and radiofrequency ablation in the treatment of the commonest kind of supraventricular tachycardia, namely atrioventricular nodal reentrant…
- Trial name
- CRYOABLATE (NCT01584154)
- Testing
- cryoablation, radiofrequency ablation
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Princess Margaret Hospital, Hong Kong