Clinical trials: Atrophic Acne Scars
Acne Scars - Mixed Atrophic and Hypertrophic
enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm Nd:YAG picosecond pulse duration laser and an investigational micro-lens array (MLA)…
- Trial name
- NCT03284333
- Testing
- other
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Acne Scars - Mixed Atrophic and Hypertrophic
Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin
Patients who have completed have completed a cumulative dose of >=120miligram/kilogram oral isotretinoin within the last 30 days, and has mild to moderate acne scarring will be randomized, into a right-left comparison study using…
- Trial name
- NCT03514771
- Testing
- Fraxel DUAL 1550/1927, oral isotretinoin, oral valacyclovir
- Volunteers
- 15 people
- Sponsor
- David Smart
Acne Vulgaris, Isotretinoin
Investigation of the Effect of Oral Isotretinoin on Skin Thickness and Elasticity in Patients With Atrophic Acne Scar
Acne scar is a common complication of acne vulgaris (AV). Early and effective treatment of AV has a crucial role in managing both acne and acne scarring.
- Conditions
- Acne Vulgaris, Isotretinoin, Atrophic Acne Scar
- Trial name
- NCT05413200
- Testing
- Isotretinoin
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Training and Research Hospital
Atrophic, Scars
Efficacy of Saline Injection Therapy in Atrophic Acne Scars
The purpose of the study was to determine the efficacy of saline injection in post-acne atrophic scars on face. All patients with mild, moderate \& severe post-acne atrophic scars, above age of 15 years without any co-morbid…
- Trial name
- NCT04197245
- Testing
- saline injection therapy in post-acne atrophic scars
- Where
- Pakistan
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Post-acne Atrophic Scars
Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars
This study compares the outcome of two procedures for the treatment of atrophic acne scars.
- Trial name
- NCT06978361
- Testing
- Microneedling with autologous Platelet Rich Plasma, Microneedling with topical insulin
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Khyber Teaching Hospital
Atrophic Acne Scar
Straberi Microneedling For Atrophic Acne
This pilot study will expand knowledge and application needling using the Straberi microneedling device for the improvement of Atrophic Acne Scarring
- Trial name
- SAA (NCT04740268)
- Testing
- Straberi
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universal Skincare Institute
Acne Scars - Mixed Atrophic and Hypertrophic
Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT04827680
- Testing
- Venus Viva MD
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Atrophic Post Acne Scarring
Comparison Between Microneedling Daycare Procedure and Tazarotene 0.1% Gel Local Application in Acne Scarring
Post acne scarring is a common complication of acne. Cosmetic appearance of the post acne facial scarring can be improved by various methods. Among the procedural methods microneedling (1) is a novel and a promising option.
- Trial name
- NCT03170596
- Testing
- tazarotene gel 0.1%, Microneedling
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acne Scars - Mixed Atrophic and Hypertrophic, Wrinkle
Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles
The objective of this clinical study is to evaluate the efficacy of fractional RF for the treatment and reduction of acne scarring or facial wrinkles.
- Trial name
- NCT04057768
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Venus Concept
Atrophic Acne Scar
2940nm Er:YAG Laser and 1927nm Thulium Laser in Improving Atrophic Acne Scars
Fractional non-ablative laser (FNAL) has been widely used in improving acne scarring. However, there was only one study reported efficacy and safety of the fractional non-ablative 1927nm thulium laser (FTL) and no studies have…
- Trial name
- NCT04813419
- Testing
- 1927nm thulium laser, 2940nm Er:YAG laser
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acne Atrophica, PRP
Poly-L-Lactic Acid Threads Versus Platelet-Rich Plasma for Post-Traumatic Atrophic Scars
This study compares the efficacy and safety of poly-L-lactic acid (PLLA) threads versus platelet-rich plasma (PRP), both combined with subcision, in the treatment of post-traumatic atrophic scars.
- Trial name
- PLLA-PRP PTAS (NCT07775092)
- Testing
- subcision and PLLA threads' insertion, PRP and subcision (PRP-S)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Tanta University
Acne Vulgaris
Fractional CO2 Laser Delivery of Topical Insulin Versus Platelet Rich Plasma in Treatment of Atrophic Post Acne Scars
compare the efficacy and safety of treating atrophic post acne scars with topical insulin versus Platelet rich Plasma PRP combined with fractional ablative Co2 laser
- Trial name
- NCT06590909
- Testing
- Fractional CO2 laser assisted PDT
- Volunteers
- 22 people
- Sponsor
- Assiut University
Atrophic Acne Scars, Acne Vulgaris
Microneedling With Glycolic Acid or Trichloroacetic Acid for Atrophic Acne Scars
Atrophic acne scars are depressed scars that can remain after acne has healed. Microneedling is a procedure that uses very small needles to create controlled micro-injuries in the skin, which may stimulate collagen production and…
- Trial name
- NCT07797517
- Testing
- Microneedling only, Microneedling with Glycolic Acid 35% Peel, Microneedling with Trichloroacetic Acid 15% Peel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Acne Scars
Lasers to Aid in Treatment of Acne Scars
To assess efficacy and safety of paired picosecond 755nm Alexandrite laser with focused lens array (PSAL; Picosure®, Cynosure, Westford, MA) and radiofrequency microneedling (RFM; Potenza™, Cynosure, Westford, MA) for treatment…
- Trial name
- NCT05579171
- Testing
- Picosecond 755nm Alexandrite Laser
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Acne Scars, Atrophic Acne Scars
Ultherapy® for the Treatment of Acne Scars
This is a prospective, multi-site trial to be conducted at 2 clinical sites. Up to 20 subjects will receive study treatments. Following study treatments, follow-up visits will occur at 60, 90 and 180 days from each subject's last…
- Trial name
- NCT02145364
- Testing
- Ultherapy® treatment
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Ulthera, Inc
Atrophic Acne Scar
Combined Procedures in the Treatment of Severe Acne Scars
Many methods utilize for acne scar treatment including laser, cosmetic filler, microneedling, local tumescent, Subcision and chemical peels. These procedures can be used individually or as a combination therapy.
- Trial name
- NCT06227481
- Testing
- Scar subcision, Platelet rich plasma injection, Polydioxanone mono threads insertion
- Volunteers
- 48 people
- Sponsor
- Al-Azhar University
Atrophic Acne Scar
Simultaneous Versus Sequential Fractional CO2 Laser and Subcision Combination for Post-acne Atrophic Scars: A Split-face Comparative Study.
Acne vulgaris, a disease of the pilosebaceous unit, is estimated to afflict 9.4% of the global population, making it the eighth most prevalent and third most significant disease according to the global burden of disease.
- Trial name
- NCT05688202
- Testing
- Simultaneous combination of fractional CO2 laser and subcision, Sequential combination of fractional CO2 laser and subcision, Fractional CO2 laser
- Where
- Vietnam
- Volunteers
- 34 people
- Sponsor
- Ho Chi Minh City Hospital of Dermato-Venereology
Acne, Atrophic Scar
Comparison of Picosecond Lasers vs. Ablative Fractional Er:YAG Lasers in Treating Atrophic Scar
The 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array (P-MLA) was a promising therapy for skin resurfacing. However, no studies have compared P-MLA with ablative fractional 2940-nm Er:YAG lasers (AF-Er) in…
- Trial name
- NCT05686603
- Testing
- a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece, a ablative fractional 2940-nm Er:YAG laser
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acne Vulgaris, Scars
Erbium-YAG Laser Versus Platelet Rich Plasma in the Treatment of Atrophic Acne Scars
This study aim to assess the efficacy of Er-YAG laser 2940nm and PRP as a single line of treatment in comparison with combined treatment in atrophic post acne scars.
- Trial name
- NCT03933033
- Testing
- Fractional Erbium Yağ Laser, Platelet Rich Plasma
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Aswan University Hospital