Clinical trials: Augmentation, open to volunteers
Horizontal Ridge Deficiency
Radiographic Assessment of Guided Cortical Shell Technique for Horizontal Ridge Augmentation
The protocol outlines a randomized clinical trial comparing two surgical techniques for horizontal ridge augmentation in the anterior mandible: Computer-Guided Autogenous Cortical Shell Technique (using a patient-specific guide…
- Trial name
- NCT06942013
- Testing
- Computer-Guided Autogenous Cortical Shell Technique (Study Group), Free-Hand Autogenous Cortical Shell Technique (Control group)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adrenoleukodystrophy, Batten Disease
UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells
The primary objective of the study is to determine the safety and feasibility of intrathecal administration of DUOC-01 in patients who are undergoing standard treatment with umbilical cord blood transplant (UCBT) for inborn…
- Conditions
- Adrenoleukodystrophy, Batten Disease, Mucopolysaccharidosis II, Leukodystrophy, Globoid Cell
- Trial name
- DUOC-01 (NCT02254863)
- Testing
- DUOC-01
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Joanne Kurtzberg, MD
Dental Implantation, Peri-Implant Soft Tissue Deficiency
Volume-Stable Collagen Matrix vs. Connective Tissue Graft for Peri-Implant Soft Tissue Defects
Peri-implant soft-tissue defects will be treated with either a volume-stable collagen matrix (VCMX; test group) or an autogenous connective tissue graft (CTG; control group) following implant placement in patients with a single…
- Conditions
- Dental Implantation, Peri-Implant Soft Tissue Deficiency, Soft Tissue Augmentation
- Trial name
- NCT07782125
- Testing
- Connective tissue graft, Volume-stable collagen matrix
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ankara University
Horizontal Alveolar Ridge Deficiency
Comparison of Two Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
This pilot randomized controlled clinical study will evaluate horizontal bone gain in patients with deficient alveolar ridges requiring horizontal ridge augmentation.
- Trial name
- NCT07865624
- Testing
- 50:50 Autogenous Bone-Xenograft, 75:25 Autogenous Bone-Xenograft
- Volunteers
- 30 people
- Sponsor
- Eslam hisham mohamed
Rotator Cuff Tear Surgical Repair
Clinical Trial to Compare Clinical and Functional Results of the Augmentation of Supraspinatus Tears With the Long Head of the Biceps Brachii Tendon
The goal of this clinical trial is to reduce the risk for re-tear in rotator cuff surgeries and improve clinical results in a working age population.
- Trial name
- NCT07657689
- Testing
- Augmented supraspinatus repair, Convencional Supraspinatus tear repair
- Volunteers
- 90 people
- Sponsor
- HOSPITAL FRATERNIDAD MUPRESPA HABANA
Peri-implant Bone and Soft Tissues
Sandwich vs. Mixed Bone Augmentation for Implant Placement
This study is being done to see which of two common grafting techniques-mixing two different grafting materials or layering two grafting materials-works better to augment bone volume next to participant's dental implant(s).
- Trial name
- NCT07832565
- Testing
- Sandwich bone augmentation, Mixed bone augmentation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Spine Injury, Cord Injury, Spinal
The Outcome of Injured Cervical Spinal Cord With Uncontrolled Swelling Under Duraplasty
Overall Objective: To assess whether incorporating duraplasty alongside bony decompression enhances motor function outcomes in individuals following Traumatic Spinal Cord Injury (TSCI).
- Conditions
- Spine Injury, Cord Injury, Spinal, Cord Infarction Spinal, Incomplete Spinal Cord Injury
- Trial name
- NCT06552507
- Testing
- Duroplasty
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Peri-Implant Health, Peri-Implant Tissues
Volumetric Analysis of Peri-Implant Soft Tissue Changes Between Polyethereketone(PEEK) Anatomic Healing Abutments and Standard Healing Abutments in Posterior Single Implant Restorations
This prospective randomized clinical trial will evaluate the clinical outcomes of the implant crown fabricated with standard scan body (control) and polyetheretherketone (PEEK) anatomic healing abutment (test).
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Soft Tissue Augmentation at Dental Implants
- Trial name
- anatomic (NCT07624331)
- Testing
- AHA PEEK, standard healing abutment
- Where
- Malaysia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- DR NUR HAFIZAH KAMAR AFFENDI
Bone Augmentation, Badly Broken Maxillary Premolars Indicated for Extraction
Comparison of Immediate Implant Placement With Titanium Mesh Versus Collagen Membrane in Type II Socket:
Statement of the problem: Immediate implant placement is faced with several problems. One of the most important issues is dealing with defects in the buccal plate of bone in the esthetic zone.
- Trial name
- NCT06875830
- Testing
- collagen membrane, titanium mesh
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Misr International University
Device Safety
Adaptive Study to Assess the Safety and Functioning of Motiva Devices on Minimally Invasive Gluteal Augmentation
The objective of this clinical trial is to assess the initial performance and safety of Motiva® Ergonomix2® Diamond®, Motiva Injector®, Motiva® Inflatable Balloon, Motiva® Reusable Channel Dissector, and Motiva® GEM Channel…
- Trial name
- GEM (NCT07135011)
- Testing
- Primary gluteal enhancement
- Where
- Costa Rica
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Establishment Labs
Anterior Maxilla Alveolar Bone Deficiency
Conventional Flap Versus Vestibular Flap in Bone Augmentation
two groups of patients both have alveolar bone deficiency in anterior maxilla, one group will be subjected to khoury bone augmentation with conventional flap the other with vestibular shifted flap
- Trial name
- (RCT) (NCT07664098)
- Testing
- vestibular shifted flap for bone augmentation, conventional flap
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Augmentation and Breast Reconstruction, Mammaplasty
Clinical Study on Tissue Preservation in Breast Augmentation and Reconstruction
This clinical study aims to evaluate the safety and effectiveness of advanced, minimally invasive techniques for breast augmentation and reconstruction.
- Conditions
- Breast Augmentation and Breast Reconstruction, Mammaplasty, Breast Augmentation, Tissue Preservation
- Trial name
- NCT07623564
- Testing
- Mia Harmonization, Mia Scarless Lift, Mia Reconstruction
- Where
- Costa Rica
- Volunteers
- 60 people
- Sponsor
- Establishment Labs
Internal Sinus Lifting
Efficacy of Adjunctive Theravex Tissue Care® With Xenograft in Internal Sinus Lifting
The purpose of this clinical study is to evaluate the clinical and radiographic efficacy of Theravex Tissue Care Plus (Bone Bioactive Liquid) as an adjunct to a xenograft in crestal maxillary sinus elevation with simultaneous…
- Trial name
- NCT07627633
- Testing
- Internal Sinus lifting using Theravex-Xenpgraft mixture, Internal Sinus lifting using Xenpgraft alone
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Horizontal Ridge Deficiency, Deficient Alveolar Bone
Evaluation of Horizontal Bone Gain of Ridge Augmentation Using Customized Porous Zirconia Shell.
Khoury technique, which employs autogenous bone blocks harvested from the patient, has been widely used for horizontal and vertical ridge augmentation.
- Trial name
- NCT07056920
- Testing
- Zirconia shell technique
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Ahmed Shawky
Treatment Resistant Psychosis, Psychosis
Stratification and Treatment in Early Psychosis Study -ASSIST
The purpose of this trial is: To investigate whether the response to clozapine treatment can be enhanced by adding cannabidiol (CBD), compared to placebo, in treatment resistant psychosis patients.
- Trial name
- STEP-ASSIST (NCT07326124)
- Testing
- CBD 100 mg/mL Oral Solution, Placeb
- Where
- 15 sites in Germany, Greece and 6 more
- Volunteers
- 250 people
- Sponsor
- University of Oxford
Bone Augmentation
Reconstruction of Deficient Maxillary Ridges Using Retromolar Blocks With and Without Collagen Membrane
Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in…
- Trial name
- NCT06900933
- Testing
- Onlay bone block covered with collagen membrane, Onlay bone block without collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Major Depressive Disorder
5-HTP and Creatine for Depression R33 Phase
This is a three-armed clinical trial examining the effect of 5-hydroxytryptophan and creatine monohydrate as augmenting agents for the treatment of depression.
- Trial name
- NCT05895747
- Testing
- Low Dose 5-hydroxytryptophan, High Dose 5-hydroxytryptophan, Low Dose Creatine Monohydrate
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Utah
Negative Symptoms in Schizophrenia, Cognition Function
tACS to Improve Negative Symptoms & Cognition in Long-term Hospitalized Schizophrenia Patients.
This study aims to evaluate the efficacy of transcranial alternating current stimulation (tACS) on negative symptoms and cognitive function in long-term hospitalized patients with schizophrenia.
- Trial name
- NCT07074704
- Testing
- Hi-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tongji University
Implant Failure, Bone Augmentation
Effect of Bone Augmentation Simultaneous to Implant Removal on the Prognosis of Reimplantation at the Same Site
The aim of this study was to investigate the effect of bone augmentation simultaneous to implant removal on the prognosis of reimplantation at the same sites, providing recommendations for management strategies after failed…
- Conditions
- Implant Failure, Bone Augmentation, Prognosis
- Trial name
- NCT07078890
- Testing
- bone augmentation simultaneous to implant removal
- Where
- 3 sites in China
- Volunteers
- 40 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Meniscus Tear Caused by a Traumatic Event, Fibrin Clot Augmentation
A Comparative Prospective Study of the Arthroscopic Meniscal Repair Methods
Performing arthroscopic meniscus repair following a traumatic meniscus tear as an alternative to a meniscectomy is now an acceptable choice.
- Conditions
- Meniscus Tear Caused by a Traumatic Event, Fibrin Clot Augmentation, Meniscal Repair
- Trial name
- NCT06176183
- Testing
- Arthroscopic meniscus repair
- Where
- 2 sites in Lithuania
- Volunteers
- 100 people
- Sponsor
- Vilnius University