Clinical trials: Autistic Spectrum Disorders
Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD)
L-theanine and Paraxanthine for Cognitive Improvement in Adults With ADHD and ASD
This pilot study will test whether combining L-theanine and paraxanthine improves sustained attention, inhibitory control, and overall cognition in adults with ADHD and ASD.
- Trial name
- NCT07189442
- Testing
- L-theanine and paraxanthine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Texas Tech University Health Sciences Center
Autism Spectrum Disorder
Movement-Based Digital Game Intervention for Children With Autism Spectrum Disorder
The goal of this study is to learn if movement-based digital games can help improve motor skills in children aged 6-10 years with Autism Spectrum Disorder (ASD).
- Trial name
- MBDG-ASD (NCT07779525)
- Testing
- Movement-Based Digital Games
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Autism Spectrum Disorder, Autism Spectrum Disorders
Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum Disorder
The goal of this clinical trial is to learn how prednisone affects adults with autism spectrum disorder (ASD). It will also learn about the safety of prednisone.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorders, Autistic Disorder, Autism
- Trial name
- PREDICT (NCT06934915)
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Christopher John McDougle, M.D.
Autism Spectrum Disorder (ASD, Autism
Assessing Outcomes of Three Different Museum-based Social Prescription Programs in Autistic Adults
This study will examine whether visiting the National Taiwan Museum can support the social and emotional well-being of autistic adults.
- Conditions
- Autism Spectrum Disorder (ASD, Autism, Autistic Spectrum Disorder (ASD)
- Trial name
- NCT07768332
- Testing
- Independent museum visit, Guided museum visits and group discussions, Museum visit with a friend
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Autism, Autism Spectrum Disorder
First CRUSH: Piloting the Preliminary Feasibility and Acceptability of the Competence in Romance and Understanding Sexual Health (CRUSH) Curriculum
The goal of this clinical trial is to learn about the feasibility and acceptability of a behavioral intervention in designed to provide sexual education and improve the behavioral skills of autistic adults for intimate…
- Trial name
- NCT05910658
- Testing
- Competence in Romance and Understanding Sexual Health (CRUSH)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Dance, Yoga, And Mindful Movement Training For ASD
The goal of this study is to learn if a dance, yoga, and mindful movement program can improve the lives of adults with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism
- Trial name
- NCT07758088
- Testing
- Yoga, dance and Mindful Movement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- USC Glorya Kaufman School of Dance
Autism Spectrum Disorder
Effects of Low Frequency Whole Body Vibrations on Motor Skills and Sensory Integration in Children With Autism
This randomized controlled trial aims to evaluate the efficacy of low-frequency Whole Body Vibration therapy on motor skills and sensory integration in children aged 5-9 years diagnosed with mild to moderate ASD.
- Trial name
- NCT07757035
- Testing
- whole body vibration, Routine physical therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Improving Social Communication in Individuals With ASD Using AI
The purpose of this study is to identify whether researched and commonly used face-to-face interventions can be effectively implemented through artificial intelligence (AI) using an application on the phone or computer.
- Trial name
- NCT05987774
- Testing
- AI Modules for Improving Social Communication
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- Stanford University
Autism Spectrum Disorder, Depressive Disorder
Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings
The goal of this clinical trial is to learn if Cognitive Behavioral Therapy for Depression in Autistic Youth (CBT-DAY) can improve depressive symptoms and related mechanisms in autistic youth aged 11-17 years with depression…
- Conditions
- Autism Spectrum Disorder, Depressive Disorder, Anxiety Disorders
- Trial name
- CBT-DAY (NCT07755137)
- Testing
- CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Children's Hospital Los Angeles
Autism Spectrum Disorder, Autistic Disorder
Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)
The primary objective of this research study is to improve outcomes involving core social-communication symptoms for young children with ASD or social communication delays by increasing access to clinically validated early…
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Active Autistic Disorder, Autism
- Trial name
- NCT05176808
- Testing
- Early Achievements- Parent Coaching Intervention
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism Spectrum Disorder
Combined Effects of Sensorimotor Integration and Post-facilitation Stretch in Autism Spectrum Disorder
To determine the effects of sensory motor integration and post facilitation stretch on toe walking and sensory processing behaviors using Foot Posture Index and Sensory Profile respectively.
- Trial name
- NCT07484347
- Testing
- Sensorimotor Integration and Post-Facilitation Stretch, Post-Facilitation Stretch
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder (ASD)
Promoting Physical Activity Among Young Children With Autism
Higher amounts of physical activity are linked to multiple health benefits including improved cognition, academic success, and classroom behavior for children.
- Trial name
- NCT07747129
- Testing
- Wellness Enhancing Physical Activity for Young Children (WE PLAY), Non-Physical Activity Online Training
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northeastern University
Autistic Disorders Spectrum
Targeting the Sensory Disturbance in Autism Spectrum Disorder
This study aims to establish a cognitive-behavior therapy (CBT) based virtual exposure (VR) exposure program to train ASD adults coping with everyday sensory scenarios.
- Trial name
- NCT05157477
- Testing
- CBT-based VR exporsure program
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit Disorder With Hyperactivity, Autistic Spectrum Disorder
Neurodevelopmental Disorders in Youth With Criminal Behaviors
1. Describe the prevalence of neurodevelopmental disorders among youth with criminal behaviors 2. Explore the relationship between specific neurodevelopmental disorders and the rates and types of crime 3.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Spectrum Disorder, Conduct Disorders in Adolescence
- Trial name
- NCT05875363
- Testing
- collect data
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder, Sleep Initiation and Maintenance Disorders
Sensory-Friendly Physical Activity for Sleep in Autistic Children
Sleep problems are very common in children on the autism spectrum and can worsen daytime behaviour, learning, and family stress. Many families have limited access to specialist sleep services.
- Trial name
- SFPAS (NCT07277101)
- Testing
- Sensory-Friendly Physical Activity Program (PAP), Conventional control group
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Xili Wen
Neurodevelopmental Disorders, Autism
Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
There are currently no approved medications for the treatment of anxiety in children and youth with neurodevelopmental disorders (NDDs), both common and rare.
- Conditions
- Neurodevelopmental Disorders, Autism, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- CALM (NCT06081348)
- Testing
- Sertraline
- Where
- 7 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Boosting Language Outcomes of Minimally Verbal Children With ASD (BLOOM)
In this project, the investigator will test the effect of augmenting an evidence based joint attention intervention (JASPER) with a motor-sound system intervention (PROMPT) compared to JASPER only on speech and language outcomes.
- Trial name
- BLOOM (NCT04218331)
- Testing
- JASPER, PROMPT
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)
ML-004-003 is a multi-center, open-label extension study that will enroll approximately 120 adolescent and adult subjects with ASD that have completed study ML-004-002.
- Trial name
- NCT05889273
- Testing
- ML-004 (IR)/(ER) tablet
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 120 people
- Sponsor
- MapLight Therapeutics
Autism Spectrum Disorder
DSM-5 Personality Disorders in Adults With Autism
Rationale: Self-report measures are frequently used for research and clinical assessments of adults with autism spectrum disorder (ASD).
- Trial name
- NCT06726187
- Testing
- Structured Clinical Interview for DSM-5 Screening Personality Questionnaire (SCID-5-SPQ).
- Where
- Netherlands
- Volunteers
- 102 people
- Sponsor
- Parnassia Groep
Autism Spectrum Disorder (ASD)
Exercise Efficacy on Autism Spectrum Disorder
The goal of this clinical trial is to learn if regular exercise intervention may improve the health status of the participants diagnosed with autism spectrum disorder, ages between 5-13 years old.
- Trial name
- NCT06831188
- Testing
- daily life exercise group, specific type exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University