Clinical trials: Autofluorescence Imaging
Gastric Cancer
A Randomized Study Comparing Autofluorescence Imaging(AFI) Followed by Narrow Band Imaging(NBI) With Videoendoscopy for the Detection of High Risk Lesions of Stomach
Videoendoscopy is the standard tool for examination of gastrointestinal tract. However, precancerous lesions and early gastric cancer can be easily missed by routine videoendoscopy.
- Trial name
- CAFBI (NCT01132534)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Sickle Cell Disease
Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease
To determine the retinal and choroidal thickness in patients with sickle cell disease compared to age, race matched population without sickle cell disease to allow a better understanding of the clinical manifestations of sickle…
- Trial name
- NCT01123369
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Colonic Polyp, Colonic Diseases
Optical Polyp Testing for In Vivo Classification
Small growths detected in the colon (polyps) during a colonoscopy may or may not have the potential to develop into cancer. However, since visual inspection alone cannot separate all potentially harmful polyps from harmless ones…
- Conditions
- Colonic Polyp, Colonic Diseases, Colonic Neoplasms, Colonic Adenoma
- Trial name
- OPTIC (NCT03139942)
- Testing
- Optical spectral reflectance and autofluorescence imaging
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Gastroesophageal Reflux Disease
Narrow-band Imaging, Autofluorescence Imaging and Gastroesophageal Reflux Disease
Aim of this study is to compare the efficacy of narrow band imaging (NBI) and autofluorescence imaging (AFI) to distinguish subtle mucosal change related to acid reflux that is not visible in standard white light imaging (WLI)…
- Trial name
- NCT01504971
- Testing
- symptom questionaire, pH monitoring, Tri-modal imaging endoscopy
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Cervical Cancer
Significance of Fluorescence Colposcopy With Autofluorescence Imaging for Cervical Cancer
Clinical Trial to access Significance of fluorescence colposcopy with autofluorescence imaging for the screening of cervical cancer
- Trial name
- NCT01854983
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Age-related Macular Degeneration
Fundus Autofluorescence Imaging in Age-related Macular Degeneration Using Confocal Scanning Laser Ophthalmoscopy
The purpose of this study is to define phenotypic variations in atrophic Age-Related Macular Degeneration (AMD) and to identify predictive factors for disease progression based on fundus autofluorescence imaging.
- Trial name
- NCT00393692
- Where
- 7 sites in Germany
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Age Related Macular Degeneration
A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)
This study proposes to use a new instrument (AO-OCT/AF: adaptive optics - optical coherence tomography/autofluorescence) combined with a data processing method to image the retinal pigment epithelium (RPE) of the eye in normal…
- Trial name
- NCT03963817
- Testing
- adaptive optics AO-OCT/AF instrument
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Retinal Disease, Retinal Degeneration
Performance of Long-wavelength Autofluorescence Imaging
Fundus autofluorescence imaging has become an important diagnostic tool in ophthalmology, guiding diagnosis and assessment of progression of retinal diseases.
- Conditions
- Retinal Disease, Retinal Degeneration, Retinal Dystrophies
- Trial name
- NCT03592017
- Testing
- Long-wavelength autofluorescence imaging
- Where
- United Kingdom
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Autofluorescence Imaging, Neuroimaging
Measurement of Retinal Auto Fluorescence With a Fluorescence Lifetime Imaging Ophthalmoscope
Fluorescent lifetime microscopy has emerged as a useful tool to study fluorescent lifetimes in vitro. Fluorescence lifetime represents the average amount of time a fluorophore remains in the excited state following excitation and…
- Trial name
- FLIO-Group (NCT01981148)
- Testing
- Fluorescence lifetime ophthalmoscope
- Where
- Switzerland
- Volunteers
- 892 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Medical Need for Fluorescein Angiography Imaging
Triton Fundus Autofluorescence and Fluorescein Angiography
Compare the image quality of the fundus autofluorescence and fluorescein angiography
- Trial name
- NCT03107104
- Testing
- Topcon DRI OCT Triton (plus), TRC-50DX retinal camera
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.