Clinical trials: Autoimmune Pancreatitis
Autoimmune Pancreatitis
Diagnostic Yield of FNA Needle and FNB Needle for Autoimmune Pancreatitis
The aim of this study is to compare the diagnostic accuracy of two EUS-guided tissue acquisition devices; the 19G Echotip Ultra Fine Needle Aspiration (FNA) device and the 20G Echotip ProCore Fine Needle Biopsy (FNB) device for…
- Trial name
- NCT03753815
- Testing
- 19G FNA needle, 20G FNB needle
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Peking Union Medical College Hospital
Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease
Treatment of IgG4-Related Disease With Revlimid and Rituximab
Among persons with Immunoglobulin G subclass 4 Related Disease (IgG4)-related disease who have persistent or recurrent disease despite standard therapies, does combination therapy with rituximab and revlimid cause a sustained…
- Conditions
- Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease, Autoimmune Pancreatitis, IgG4-related Sclerosing Cholangitis
- Trial name
- TIGR2 (NCT02705638)
- Testing
- Rituximab, Lenalidomide
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic
Artificial Intelligence in EUS for Diagnosing Pancreatic Solid Lesions
We aim to develop an EUS-AI model which can facilitate clinical diagnosis by analyzing EUS pictures and clinical parameters of patients.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic, Pancreatic Neuroendocrine Tumor, Autoimmune Pancreatitis
- Trial name
- NCT05476978
- Testing
- EUS-AI model
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology
Pancreatitis
Genetic Analysis for Predicting of Relapse During Steroid Treatment for Autoimmune Pancreatitis (AIP)
To determine whether certain alleles or haplotypes of major histocompatibility complex gene are associated with AIP in Korean population, we undertook this study with high-resolution typing for HLA (sequence-based typing).
- Trial name
- NCT00444444
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Pancreatic Cancer, Pancreatitis
Validation of Joint-AI in Diagnosing Pancreatic Solid Lesions
This clinical trial aims to learn if a multimodal artificial intelligence (AI) model can enhance the diagnosis of pancreatic solid lesions. The main questions it aims to answer are: 1.
- Conditions
- Pancreatic Cancer, Pancreatitis, Pancreatic Neuroendocine Neoplasms (pNETs), Autoimmune Pancreatitis
- Trial name
- NCT06753318
- Testing
- The assistance of the Joint-AI model, The assistance of the interpretable Joint-AI model
- Where
- China
- Volunteers
- 716 people
- Sponsor
- Huazhong University of Science and Technology
Autoimmune Pancreatitis, IgG4-Related Diseases
Validation of the Odesa Criteria 2026 for Autoimmune Pancreatitis
This ambispective observational study aims to validate the Odesa Criteria 2026 (OC26), a flexible domain-based point scoring system for diagnosing autoimmune pancreatitis.
- Conditions
- Autoimmune Pancreatitis, IgG4-Related Diseases, Pancreatic Cancer, Chronic Pancreatitis
- Trial name
- ОС26 (NCT07536841)
- Testing
- No intervention (observational study)
- Where
- 2 sites in Ukraine
- Volunteers
- 82 people
- Sponsor
- Military Medical Clinical Center of the Southern Region, Ukraine
Type 1 AIP
Inebilizumab for the Treatment of Patients With Type 1 Autoimmune Pancreatitis
Autoimmune pancreatitis (AIP) is an immune-related inflammatory disease of the pancreas. Relapse can occur after treatment, and long-term treatment with glucocorticoids and conventional immunosuppressants can cause significant…
- Trial name
- NCT07862075
- Testing
- Inebilizumab
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruijin Hospital
Pancreatic Ductal Adenocarcinoma, Chronic Pancreatitis
CT Pancreas Perfusion
1. Pancreatic CT perfusion with a biofeedback breathing belt worn by the participant, and using novel post-processing techniques, is a reliable method which can be used to differentiate between pancreatic cancer, chronic…
- Conditions
- Pancreatic Ductal Adenocarcinoma, Chronic Pancreatitis, Autoimmune Pancreatitis
- Trial name
- NCT00588367
- Testing
- Mayo Interactive Breath Hold Monitor
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Chronic Liver Disease
An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis
Hepatic steatosis may cause inflammation and fibrosis within the liver potentially leading to end-stage liver disease cirrhosis, liver failure and death.
- Trial name
- FALL (NCT05335603)
- Where
- Denmark
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Type 1 Diabetes (T1D), Diabetes Secondary to Pancreatitis
Digital Mindfulness for Young Adults With Type 1 Diabetes
The purpose of this research study is to test a mindfulness app called Calm Health among young adults with type 1 diabetes or other absolute insulin deficiency diabetes.
- Trial name
- NCT07062887
- Testing
- Mindfulness app
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Type 1 Diabetes (T1D), Latent Autoimmune Diabetes in Adult (LADA)
Building and Sustaining Exercise Habits for Adults With Type 1 Diabetes
The challenges of living with type 1 diabetes often stand in the way of getting enough exercise. Continuous blood sugar monitoring has revolutionized type 1 diabetes care but remains underutilized to sustainably support exercise…
- Conditions
- Type 1 Diabetes (T1D), Latent Autoimmune Diabetes in Adult (LADA), Pancreatitis
- Trial name
- NCT06967701
- Testing
- Exercise program, Self-monitoring
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Oral Microbiota, Pancreatitis
The Characteristics of Oral Microbiota in Chronic Pancreatitis and Autoimmune Pancreatitis
There are more than 700 different bacteria colonized in human oral cavity, which are collectively referred to as oral microbiota.
- Conditions
- Oral Microbiota, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT07015580
- Testing
- 16S rRNA sequencing
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Autoimmune Pancreatitis
Evaluation of EUS-guided FNA for Diagnosing Autoimmune Pancreatitis
The aim is to evaluate EUS-FNA efficacy for AIP diagnosis using a 22-gauge (G) needle.
- Trial name
- NCT03241797
- Testing
- EUS-FNA
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Bin Cheng
Autoimmune Pancreatitis
Prospective Study on the Role of Eus-fnb in the Diagnosis of Autoimmune Pancreatitis
According to the reported histological procurement yield of the end-cutting needles, the investigators supposed that the use of EUS-FNB in probable AIP patients, generally aimed only to rule-out malignancy, could provide…
- Trial name
- BIO_AIP (NCT04397731)
- Where
- 2 sites in Italy, Japan
- Volunteers
- 52 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pancreatitis, Inflammatory Bowel Diseases
Thiopurine Induced Pancreatitis in IBD Patients
Azathioprine (AZA) and its metabolite 6-mercaptopurine (6-MP) were developed over 50 years ago by Gertrude Elion and George Hitchings and were initially used clinically in the management of childhood leukemia and organ…
- Trial name
- NCT02281799
- Testing
- Azathioprine
- Where
- Israel
- Sponsor
- Shaare Zedek Medical Center
Retroperitoneal Fibrosis, Autoimmune Pancreatitis
Rituximab in IgG4-RD: A Phase 1-2 Trial
The primary objective of this study is to evaluate the safety and effectiveness of rituximab in IgG4-RD.
- Conditions
- Retroperitoneal Fibrosis, Autoimmune Pancreatitis, Sialadenitis, Pseudotumor
- Trial name
- NCT01584388
- Testing
- Rituximab
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Mesenchymal Tumor, Autoimmune Pancreatitis
Evaluation of a New EUS Guided Biopsy Needle (SharkCore) Comparing to Standard EUS Needle (ProCore)
Diagnosis of lesions of pancreas, the upper gastrointestinal tract, as well as adjacent structures, such as lymph nodes, is still showing advancements especially with the increased use of endoscopic ultrasound.
- Conditions
- Mesenchymal Tumor, Autoimmune Pancreatitis, Lymphoma, Solid Tumors
- Trial name
- NCT02766842
- Testing
- EUS-FNB with ProCore needle, EUS-FNB with SharkCore needle, ProCore needle
- Where
- United States
- Sponsor
- Johns Hopkins University
Type 1 AIP
A Trial on the Remission Rates of Type I Autoimmune Pancreatits With High-risk of Recurrence
Autoimmune pancreatitis (AIP) is an autoimmune disease with low incidence rate and involving the pancreas. In China, type I AIP is predominant. Glucocorticoids (GC) have a significant therapeutic effect.
- Trial name
- AIP；MMF (NCT06468709)
- Testing
- Glucocorticoids, Glucocorticoids+MMF
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Ruijin Hospital
Type1diabetes
Assay for the Pancreatic Polypeptide: an Help for Clinical Practice Guidelines in Classification of the Diabetes
The purpose of this study is to evaluate global endocrine function within type 1 and type 3c diabetic patients, helping pancreatic polypeptide measurement.
- Trial name
- DIAPP (NCT03396146)
- Testing
- 12 ml total blood tubes volume, Fecal sample
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris