Clinical trials: Autonomic Nervous System Disorders
Autonomic Nervous System
The Effect of Endovascular Thrombectomy on Autonomic Nervous System in Patients With Large-vessel Ischemic Stroke
The autonomic nervous system (ANS), regulating involuntary physiologic processes including heart rate and blood pressure, is affected by changes in the cerebral vessels like carotid artery stenosis, occlusion, carotid artery…
- Trial name
- AFFRICATE (NCT05099354)
- Testing
- autonomic nervous system testing
- Volunteers
- 20 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Diabetes Mellitus, Hypoglycemia
Mechanisms of Hypoglycemia Associated Autonomic Failure
Intensive glucose control in type 1 diabetes mellitus (T1DM) is associated with clear health benefits. However, despite development of insulin analogs, pump/multi-dose treatment and continuous glucose monitoring, maintaining…
- Conditions
- Diabetes Mellitus, Hypoglycemia, Autonomic Failure
- Trial name
- NCT00678145
- Testing
- naloxone, fructose, exercise
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Cluster Headache
An Open Label Study Using Consecutive Intravenous Depacon With Oral Depakote ER for the Treatment of Cluster Headaches.
The purpose of this study is to collect and evaluate information on the use of Depakote Extended Release (ER) and Depacon Intravenous (IV) in patients with cluster headaches.
- Trial name
- NCT00203242
- Testing
- Depacon IV and Depakote ER
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Thomas Jefferson University
Orthostatic Hypotension
State of Knowledge Among Nurses Regarding the Screening for Orthostatic Hypotension in Elderly Individuals in Acute Geriatric Medicine and Medical and Rehabilitation Services
Orthostatic hypotension is a common geriatric syndrome associated with an increased risk of falls, syncope, functional decline and mortality in older adults.
- Trial name
- HTO-IDE (NCT07738666)
- Testing
- Administration of questionnaires on nurses' knowledge of orthostatic hypotension, its measurement, diagnosis and management
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hôpital NOVO
Chronic Fatigue Syndrome
Hydrogen Water Intervention With Heart Rate Variability as an Outcome Biomarker in ME/CFS
The goal of this clinical trial is to learn if the OTC supplement, hydrogen water, works to treat the fatigue-related symptoms and functional limitations in adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- NCT07009691
- Testing
- Hydrogen water which is prepared from an OTC supplement.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stony Brook University
Parkinson's Disease, Multiple System Atrophy
Botulinum A Toxin in Patients With Parkinson's Disease
The researchers investigated the effectiveness and safety of BoNT/A injected into the detrusor muscle in patients with PD and MSA all of whom had detrusor muscle overactivity unresponsive to conventional medical therapy.
- Conditions
- Parkinson's Disease, Multiple System Atrophy, Detrusor Overactivity
- Trial name
- Botox-PD (NCT00822913)
- Testing
- Intravesical injection of Botulinum A toxin
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Cluster Headache
Physiotherapy Program for Cluster Headache
This study evaluates the effectiveness of physiotherapy program in the treatment of cluster headaches. Half of participants will receive a program of physiotherapy and usual drugs, while the other will receive an exercise program…
- Trial name
- PhyCH (NCT02460003)
- Testing
- Physiotherapy, Home exercise program
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- AG Clinic
Complex Regional Pain Syndrome Type I of the Upper Limb, Unilateral Limb Pain of Other Origin
Correlation Between 3 Phase Bone Scintigraphy and Pressure Pain Thresholds in Patients With Complex Regional Pain Syndrome (CRPS)
The aim of the study is to investigate the correlation between increased bone metabolism in the 3 phase bone scintigraphy (TPBS) and decreased pressure pain thresholds in patients with complex regional pain syndrome (CRPS) of the…
- Conditions
- Complex Regional Pain Syndrome Type I of the Upper Limb, Unilateral Limb Pain of Other Origin, Healthy Subjects
- Trial name
- NCT01623141
- Testing
- Pressure Pain measurement
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Pain, Chronic
Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults
This study is designed to test if the use of virtual reality (VR) can improve chronic pain related to CRPS. One way is to use virtual reality.
- Trial name
- NCT05888142
- Testing
- in clinic pain VR reduction exercises, In clinic VRpain reduction exercises + VR homeworks
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Washington
Restless Legs Syndrome
Autonomic Assessment in Patients With Restless Legs Syndrome
Restless legs syndrome (RLS) is a sensorimotor, sleep-related disorder characterized by urgency to move the legs during inactivity or resting state.
- Trial name
- NCT04906486
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Parkinson Disease, Multiple System Atrophy
Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis - Part 2
Parkinson's disease (PD) is the second most common neurodegenerative disease. Multiple system atrophy (MSA) is a relentlessly progressing rare neurodegenerative disease of unknown etiology.
- Trial name
- Voice4PD-MSA (NCT05807373)
- Testing
- voice recordings
- Where
- 2 sites in France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Symptomatic Bradycardia, Autonomic Nervous System Diseases
Basic and Clinical Study of Cardiac Ganglion Catheter Ablation for the Treatment of Significant Bradycardia
This study adopts a strategy combining basic research with clinical investigation to systematically explore the therapeutic value of cardioneuroablation in the treatment of vagally-mediated bradycardia.
- Trial name
- NCT07468383
- Testing
- Cardioneuroablation
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Beijing Anzhen Hospital
Parkinson Disease
Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D
The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D Main questions it aims to answer are: 1.
- Trial name
- NCT07084597
- Testing
- Vitamin D
- Where
- Bangladesh
- Volunteers
- 15 people
- Sponsor
- Bangladesh Medical University
COVID-19
Cardiovascular Assessment in Patient Recovered From COVID-19 and Recovery of Autonomic Nervous System in Association With the Severity of the Disease
The goal of the study is to assess autonomic nervous system and cardiovascular controll during orthostatic challenge in 90 patients recovered from COVID-19 and devided into three groups depend on severity of the morbidity.
- Trial name
- COVIDans (NCT05081362)
- Testing
- Non invasive cardiovascular monitoring with CNAP device of arterial pressure, ECG and respiratory activity
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- IRCCS Policlinico S. Donato
Complex Regional Pain Syndrome Type I of the Upper Limb
Contribution of Immersive Virtual Reality to a Standardized Rehabilitation Program for Upper Limb Chronic Pain: A Single-Case Experimental Design Study
Background: Chronic pain represents a significant public health concern, given its high prevalence and the substantial impact it has on the quality of life of many individuals affected.
- Trial name
- ReVIDoC (NCT06523361)
- Testing
- H'ability
- Where
- 2 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Angers
Complex Regional Pain Syndrome
Comparative Effects of Mirror Therapy and Standard Physiotherapy in Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a chronic pain condition characterized by persistent pain, sensory disturbances, motor dysfunction, and functional impairment, often following trauma or surgery.
- Trial name
- (CRPS) (NCT07332884)
- Testing
- Mirror Therapy, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- University of Lahore
Orthostatic Intolerance, Orthostatic Hypotension
Pathophysiologic Hemodynamics After Primary Unilateral Total Hip Arthroplasty in Patients Receiving ACEIs and ARBs
Incidence and pathophysiologic hemodynamics of postoperative orthostatic intolerance and orthostatic hypotension in patients receiving antihypertensives
- Trial name
- NCT04842058
- Testing
- Mobilisation procedure
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Hvidovre University Hospital
Complex Regional Pain Syndromes
Evoked Fields After Median and Ulnar Stimulation
In order to be able to study the effects of evoked fields with magnetoencephalography (MEG) in two groups of patients, comparison is made with a group of healthy volunteers.
- Trial name
- NCT00217243
- Testing
- Evoked fields before and after a local block (Xylocaine)
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical Center Alkmaar
Syncope, Vasovagal
Heart Rate Variation in Females Predicts Tilt Test Results
Head-up tilt test (HUTT) is widely used to evaluate patients with unexplained syncope, but data on clinical predictors of HUTT results are limited.
- Trial name
- NCT06496074
- Testing
- Head-up Tilt Test
- Where
- Brazil
- Volunteers
- 149 people
- Sponsor
- Federal University of Piaui
Parkinson's Disease, Multiple System Atrophy
Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease
The gut may be a portal of entry for agents that cause or contribute to the causes of Parkinson's disease (PD). The investigators are studying changes in the normal population of gut flora and in intestinal permeability and their…
- Trial name
- NCT01155492
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
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