Clinical trials: Autonomous Nervous System
Parkinson's Disease
[11C]Donepezil PET For Imaging The Autonomous Nervous System In Parkinsons Disease
AIM: Investigate wether there are differences in the parasympathetic nervous system in Parkinsons patients compared to controls. MATERIALS AND METHODS: We use the tracer [11C]donepezil to image the parasympathetic nervous system.
- Trial name
- NCT02012595
- Testing
- [11C]donepezil PET
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Per Borghammer
Parkinson Disease
Parkinson Disease Before and After Medication and Rehabilitation Treatment
In this three-year project, our research teams are going to consecutively explore these important clinical, drug and physical rehabilitation treatment effects, noradrenergic network, autonomic dysfunction and microRNA signalling…
- Trial name
- NCT02672943
- Testing
- Rehabilitation treatment, non-rehabilitation treatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Heart Rate Variability
Short- and Long-term HRV Measurements After Osteopathic Myofascial Thoracic Manipulations
The adaptation of the heart to react to any stimulus is called heart rate variability (HRV). Moreover, HRV is now used as a health index.
- Trial name
- NCT04234958
- Testing
- Osteopathic manipulative treatment
- Where
- Canada
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Cerebral Hematoma, Traumatic, Intracerebral Hemorrhage, Traumatic
Interest of Real Time Measurement of Autonomous Nervous System for the Detection of Brain Death
Context: A major lack of organ donors is a serious public health problem. It determines a prolonged delay before a transplant can be performed and thus a significant number of deaths of patients waiting for transplantation.
- Conditions
- Cerebral Hematoma, Traumatic, Intracerebral Hemorrhage, Traumatic, Traumatic Brain Hemorrhage, Traumatic Brain Injury
- Trial name
- MEANS (NCT00918970)
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Post-traumatic Stress Disorder
Clinical Study About the Effects of Scuba Diving on Post Traumatic Stress Disorder (PTSD)
Post-traumatic stress disorder (PTSD) is a set of symptoms that can be developed as a result of exposure to a traumatic event or events that can range in prevalence from 25% to 75%.
- Trial name
- DIVE4NICE (NCT04343924)
- Testing
- Scuba diving activities, Virtual reality activities
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cranial Neurosurgery
Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial Neurosurgery
Patients undergoing cranial neurosurgery face a high-risk postoperative period, particularly during emergence from anesthesia and early recovery in the post-anesthesia care unit (PACU).
- Trial name
- HERO-PACU (NCT07443072)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Breast Surgery, Thoracic Paravertebral Block
Effect of Thoracic Paravertebral Block on Heart Rate Variability (HRV)
The Left thoracic paravertebral block have a different effect on heart's autonomic nervous system, as measured with Heart Rate Variability, compared to Right interscalene block
- Conditions
- Breast Surgery, Thoracic Paravertebral Block, HRV, Autonomic Nervous System
- Trial name
- NCT01755910
- Testing
- Left thoracic paravertebral block, Right thoracic paravertebral block
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Larissa University Hospital
Premature Birth
Assessment of Autonomic Regulation During the Listening of Mother Heart Beat in Newborns
Prematurity birth lead to an early breaking link with the in utero environment. A special attention is brought in the neonatal intensive care units to reduce noise and lighting surrounding aiming to protect the newborn.
- Trial name
- Cardio_Sound (NCT04821011)
- Testing
- electronic stethoscope, acoustic listening of mother's heartbeats, Recording of the newborn's heart rate
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Feeding and Eating Disorders
Improving Gastrointestinal Function In High-Risk Newborns By Stimulation Of The Enteric Nervous System
The goal of this therapeutical intervention trial is to investigate whether tactile-kinesthaetic and oral sensorimotor stimulation can improve gastrointestional function in preterm infants born before gestational age of 30 weeks…
- Trial name
- NeoHemoHapt (NCT06057415)
- Testing
- HAPTOS (Handling Adapted to Postnatal age with Tactile-kinaesthetic and Oral sensorimotor Stimulation
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Radboud University Medical Center
Postoperative Confusion, Postoperative Delirium
Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
The goal of this randomized, double blinded study is to examine in children whether postoperative agitation can be reduced. The main question it aims to answer is Will optimized, monitor guided analgesic treatment and…
- Conditions
- Postoperative Confusion, Postoperative Delirium, Postoperative Pain, Acute, Postoperative Complications
- Trial name
- ANNA (NCT05785689)
- Testing
- Dexmedetomidine
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Autonomic Nervous System Diseases
Sympathetic-parasympathetic Ratio of Our Gaze
ABSTRACT BACKGROUND The existence of the retinohypothalamic pathway suggests that light may influence autonomic outflow activity.
- Trial name
- NCT03322904
- Testing
- iris photography
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Cushing Syndrome
Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)
Cushing syndrome (CS) is an endocrine disorder caused by chronic exposure to glucocorticoid (GC) excess. Endogenous CS has an estimated incidence of 0.2 to 5.0 cases per million per year and prevalence of 39 to 79 cases per…
- Trial name
- NCT04543253
- Testing
- MUSE biofeedback
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Mayo Clinic
Congestive Heart Failure
Effect of Bi-ventricular Pacing on Autonomous Nervous System
Patients with congestive heart failure are often associated with delayed intraventricular depolarization which causing dyssynchrony and an inefficient pattern of left ventricular contraction.
- Trial name
- NCT00190138
- Testing
- Bi-ventricular pacing
- Sponsor
- Far Eastern Memorial Hospital
Shoulder Surgery, Interscalene Nerve Block
Effect of 0.5% vs 0.375% Ropivacaine on Autonomous Nervous System
It is established that the local anesthetic that is administered during an interscalene block affects the autonomic outflow to the heart.
- Conditions
- Shoulder Surgery, Interscalene Nerve Block, Ropivacaine
- Trial name
- NCT02125994
- Testing
- Interscalene nerve block
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Larissa University Hospital
Critical Illness, Pain
Pervasive Sensing and AI in Intelligent ICU
Important information related to the visual assessment of patients, such as facial expressions, head and extremity movements, posture, and mobility are captured sporadically by overburdened nurses, or are not captured at all.
- Conditions
- Critical Illness, Pain, Delirium, Confusion
- Trial name
- NCT05127265
- Testing
- Video Monitoring, Accelerometer Monitoring, Noise Level Monitoring
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Florida
Parkinson's Disease (PD)
A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease
The purpose of this research study is to examine the effects of a 3-month personalized community-based walking program using a digital music-based device designed for self-directed gait training in people with Parkinson disease…
- Trial name
- MyMusiQ (NCT07705373)
- Testing
- MR-005 (MedRhythms, Inc., Portland, ME)
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Boston University Charles River Campus
Fear Avoidance
Knowledge, Attitudes, and Beliefs About Musculoskeletal Pain Among Primary Care Health Professionals in Spain.
Pain is influenced by psychological and emotional factors, and healthcare professionals may unintentionally contribute to chronic disability by reinforcing fear and limiting normal activity.
- Trial name
- CACDAPES (NCT06900231)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Universitat de Lleida
Insomnia, Sleep Quality
The Effects of Autonomous Sensory Meridian Response (ASMR) on Sleep Quality Improvement in Adolescents
Background: This study explored the therapeutic impact of ASMR on sleep problems in high school students. Methods: The study involved sixty participants, divided evenly into four groups: three intervention groups (A, B, C) and…
- Trial name
- ASMR on sleep (NCT06597110)
- Testing
- listened to ASMR
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
CMT - Charcot-Marie-Tooth Disease, CMT1A
AUTONOMOUS DISORDERS IN CMT
Hereditary neuropathies are a phenotypically and genetically heterogeneous group of disorders. One of the most common forms is Charcot-Marie-Tooth neuropathy (CMT), which can be further divided into demyelinating (CMT1) and…
- Conditions
- CMT - Charcot-Marie-Tooth Disease, CMT1A, CMT (Charcot Marie Tooth Disease)
- Trial name
- CMT-autonom (NCT07570446)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Parkinson Disease
Driving Performance of People With Parkinson's Using Autonomous In-Vehicle Technologies
For drivers with Parkinson's Disease (PD), autonomous in-vehicle technologies may help mitigate functional deficits, improve driving performance, decrease driving errors and enhance their ability to stay on the road.
- Trial name
- NCT04660500
- Testing
- PD Drivers Using AV Technologies On-road
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Florida