Clinical trials: Axillary Lymph Nodes Dissection
Postoperative Pain, Breast Cancer
Erector Spinae Plane Block Versus Serratus Plane Block for Breast Surgery
Serratus plane block (SPB) was first described in 2013 by Blanco and designed to primarily block the thoracic intercostal nerves.
- Trial name
- NCT03538483
- Testing
- Bupivacaine Hcl 0.25% Inj, Bupivacaine HCl Inj 0.25%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Lymphedema, Breast Cancer
Arm Circumference Measurement With or Without Bioimpedance Spectroscopy in Finding Lymphedema Early in Patients With Stage I-III Breast Cancer
This randomized pilot clinical trial studies arm circumference measurement with or without bioimpedance spectroscopy in finding extra lymph node fluid build up in the arm (lymphedema) early in patients with stage I-III breast…
- Trial name
- NCT03648983
- Testing
- arm circumference measurement, Bioimpedance spectroscopy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Albert Einstein College of Medicine
Lymphedema
Lymphedema Following Hand/Wrist Surgery in Women Post Axillary Node Dissection
This is a prospective, randomized, equivalence trial designed to evaluate postoperative complications following hand surgery with a brachial tourniquet and without a tourniquet in patients that have previously had a mastectomy…
- Trial name
- NCT00984269
- Testing
- Tourniquet Use
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Breast Cancer Lymphedema
ILR to Prevent BRCL_MCC 23608
The goal of this clinical trial is to evaluate the effectiveness of Immediate Lymphatic Reconstruction (ILR) in preventing breast cancer-related lymphedema (BCRL) in high-risk patients.
- Trial name
- NCT07127003
- Testing
- Immediate Lymphatic Reconstruction
- Where
- 3 sites in United States
- Volunteers
- 98 people
- Sponsor
- University of South Florida
Node-positive Breast Cancer
Axillary Node Dissection w or w/o LVB in Node Positive Breast Cancer Patients
Lymphedema is a devastating complication of breast cancer surgery that decreases the quality of life of up to 40% of breast cancer survivors.
- Trial name
- NCT05970107
- Testing
- Axillary Lymph Node Dissection, Axillary Reverse Mapping, Lymphaticovenous Bypass
- Volunteers
- 400 people
- Sponsor
- Case Comprehensive Cancer Center
Lymph Node Dissection, Lymphoedema
A Study for Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Radical Lymph Node Dissection
Patients undergoing groin or axillary Radical lymph node dissection (RLND) or completion lymph node dissection (CLND, after positive sentinel lymph node biopsy (SLNB) for melanoma or breast cancer were randomized in a controlled…
- Conditions
- Lymph Node Dissection, Lymphoedema, Lymphocoele
- Trial name
- NCT02476357
- Testing
- Harmonic scalpel
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Lausanne Hospitals
Breast Cancer Related Lymphedema
Identification and Preservation of Arm Lymphatics
Controversy in axillary reverse mapping in axillary lymph node dissection (ALND) possibly results from incomplete recognition of the arm lymphatic system (ALS) and its compromise to oncological safety.
- Trial name
- DEPART (NCT04446494)
- Testing
- Identification and preservation of arm lymphatics (DEPART)
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Wuhan University
Breast Cancer
Breast Lymph Node Mapping
The purpose of this study is to map the arm lymphatic drainage system in the axilla with blue dye and the breast drainage system with a radioactive material.
- Trial name
- NCT01038908
- Testing
- Isosulfan Blue (Patent Blue Dye V)
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Axillary Lymph Node Dissection, ALND
Evaluating Hemopatch in Reducing Seroma Related Complications Following Axillary Lymph Node Dissection: a Pilot Study
To evaluate if the use of Hemopatch in axillary lymph node dissection shows potential in reducing clinically significant seroma and seroma related complications, which might serve as a basis for a randomized controlled trial.
- Conditions
- Axillary Lymph Node Dissection, ALND, Axillary Clearance, Seroma
- Trial name
- HEIDI (NCT04185480)
- Testing
- Hemopatch
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Zuyderland Medisch Centrum
Breast Cancer, Axillary Lymph Nodes Dissection
Audit of Targeted Sentinel Node Biopsy (TSNB) in Patients With Limited Nodal Disease Undergoing Primary Surgery
Axillary ultrasound scan (AUS) is routinely employed in the UK for preoperative axillary staging and can diagnose approximately 50 - 80% of node positive patients when combined with percutaneous needle biopsy techniques (either…
- Conditions
- Breast Cancer, Axillary Lymph Nodes Dissection, Axillary Metastases, Sentinel Lymph Node Biopsy (SLNB)
- Trial name
- NodeSMART (NCT07085442)
- Testing
- Targeted Sentinel Node Biopsy (TSNB)
- Where
- 14 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Breast Cancer, Breast Neoplasms
Augmented-Reality ICG Fluorescence Second-Look for Residual Nodal Disease After Axillary Dissection in Breast Cancer
This study tests whether special imaging goggles can help surgeons find lymph nodes that may be left behind during breast cancer surgery.
- Conditions
- Breast Cancer, Breast Neoplasms, Sentinel Lymph Node, Lymphatic Metastasis
- Trial name
- AR4SLN (NCT07696754)
- Testing
- Augmented-reality ICG fluorescence second-look imaging
- Where
- North Macedonia
- Volunteers
- 30 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Breast Cancer
Selective Axillary Lymph Node Dissection Vs Complete Axillary Dissection: A Randomised Clinical Trial to Assess the Prevention of Lymphedema in Breast Cancer Treatment
This is a pilot study at the National Cancer Institute (INT) of Milan evaluated the feasibility of selective axillary dissection (SAD) which preserved the lymphatic drainage of the arm.
- Trial name
- NCT03083314
- Testing
- SELECTIVE AXILLARY LYMPH NODE DISSECTION (SAD), COMPLETE AXILLARY DISSECTION (ALND)
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Breast Cancer
Lymph Node Removal in Treating Women Who Have Stage I or Stage IIA Breast Cancer
RATIONALE: Surgery to remove lymph nodes in the armpit may remove cancer cells that have spread from tumors in the breast. PURPOSE: Randomized phase III trial to determine the effectiveness of removing lymph nodes in the armpit…
- Trial name
- NCT00003855
- Testing
- axillary lymph node dissection, whole breast irradiation
- Where
- 156 sites in United States, Australia and 2 more
- Volunteers
- 605 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Breast Cancer
POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer
POSNOC is a pragmatic, randomised, multicentre, non-inferiority trial. Aim For women with early stage breast cancer and one or two sentinel node macrometastases, to assess whether adjuvant therapy alone is no worse than adjuvant…
- Trial name
- POSNOC (NCT02401685)
- Testing
- Adjuvant therapy, Axillary treatment
- Where
- 50 sites in Australia, New Zealand and 1 more
- Volunteers
- 1,900 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Breast Cancer
T1-T2 Breast Cancer: Comparison Between Removal and Preservation of Axillary Lymph Nodes (SINODAR ONE)
Italian Multicentric non inferiority two-arm randomized clinical trial to verify that the experimental treatment (omission of axillary lymph node intervention) in the presence of sentinel lymph node metastases does not lead to a…
- Trial name
- SINODAR ONE (NCT05160324)
- Testing
- Removal of axillary lymph nodes., Preservation of axillary lymph nodes
- Volunteers
- 889 people
- Sponsor
- Fondazione Humanitas per la Ricerca
Melanoma
Fibrin Melanoma Axillary Node Study in Patients With Melanoma
Primary Objective: To determine whether the use of a fibrin sealant applied to axillary soft tissues following node dissection can result in earlier drain removal.
- Trial name
- NCT00504582
- Testing
- Fibrin Sealant
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Neoplasms
Study of Fluorodeoxyglucose (FluGlucoScan) in Patients With Breast Cancer: Correlation With Histologic Findings of Sentinel Node Biopsies and Axillary Dissection
Breast cancer affects many women. One of the places to which it can spread is the lymph glands under the arm. The type of treatment offered to patients often will depend on whether those lymph glands have cancer in them or not.
- Trial name
- NCT00123799
- Testing
- Positron Emission Tomography Imaging
- Where
- Canada
- Volunteers
- 199 people
- Sponsor
- AHS Cancer Control Alberta
Breast Carcinoma, Breast Carcinoma Metastatic in Lymph Node
Magseed and Magtrace Localization for Breast Cancer
The aim of this study is to compare the efficacy of the Sentimag localization system and its tracer Magtrace, superparamagnetic iron oxide nanoparticles, as a tracer in sentinel node biopsy in breast cancer with Tc99 in a…
- Trial name
- NCT05161507
- Testing
- Magseed, Magtrace, Axillary lymph node metastasis - needle biopsy
- Where
- Czechia
- Volunteers
- 70 people
- Sponsor
- University Hospital Ostrava
Breastcancer, Mastectomy
Study Evaluating the Efficacy of Loco-regional Anaesthesia PECS on Chronic Pain of a Mastectomy
A non-randomized, mono-centric, prospective interventional study that will assess the efficacy of the loco-regional anesthesia PECS on the rate of chronic pain, 6 month after a patient will have either received a mastectomy or a…
- Trial name
- PECS (NCT03023007)
- Testing
- Loco-regional anaesthesia
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Oscar Lambret
Breast Cancer, Muscle Strength
Effectiveness of PNF Training for Improving for Muscle Strength, Function, and Pain After Axillary Lymph Node Dissection
Breast cancer is the most common type of cancer affecting women of all ages worldwide. Advanced and comprehensive treatment options have increased survival rate and life expectancy, necessitating a focus on the complications of…
- Trial name
- NCT05288036
- Testing
- Proprioceptive Neuromuscular Rehabilitation group, Progressive Resistance Exercise Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital