Clinical trials: Back; Instability
Low Back Pain, Spondylolisthesis
Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain
Lumbar spinal fusion was introduced approximately 70 years ago and has evolved as a treatment option for symptomatic spinal instability, spinal stenosis, spondylolisthesis, and degenerative scoliosis.
- Conditions
- Low Back Pain, Spondylolisthesis, Spondylosis, Spinal Instability
- Trial name
- NCT01918943
- Testing
- PLIF and Aspen (spinous process fixation device)
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- American British Cowdray Medical Center
Segmental Instability Post-laminectomy
Safety and Efficacy in Pain Reduction of CT-Guided Screw Fixation for Post-laminectomy Surgery Segment Spinal Instability: A Monocentric Study of 24 Patients (2023-2026)
Segmental instability of the spine following laminectomy or surgical arthrodesis is a common complication that often requires additional surgical intervention.
- Trial name
- NCT07443267
- Testing
- No intervention
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Spinal Instability
Comparative Study of Arthrodeses by "Single Posterior Approach" and by "Double Anterior and Posterior Approach"
Extended arthrodesis of the spine is indicated in the treatment of deformities. The principle of the intervention is to correct the spinal imbalance and to obtain a fusion of the vertebral segment operated in order to guarantee…
- Trial name
- ARBORD (NCT03876275)
- Where
- France
- Volunteers
- 193 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Lumbar Spine Instability
Effects of Core Stabilization Exercise on Balance
Recent studies indicate that patients with chronic low back pain (LBP) present problems in balance. Alterations in proprioception are the possible causes of alteration of postural balance in LBP.
- Trial name
- NCT02200913
- Testing
- core stabilization exercise, general trunk strengthening exercise
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Degenerative Spondylolisthesis or Retrolisthesis, Spinal Stenosis
A Clinical Study of the Dynesys(R) Spinal System
This non-inferiority study will compare the clinical outcomes of subjects implanted with the Dynesys Spinal System versus the clinical outcomes of subjects implanted with an instrumented posterior lateral spinal fusion.
- Conditions
- Degenerative Spondylolisthesis or Retrolisthesis, Spinal Stenosis, Stenosing Lesion.
- Trial name
- NCT00759057
- Testing
- Posterior Pedicle Screw System
- Where
- 26 sites in United States
- Volunteers
- 399 people
- Sponsor
- Zimmer Biomet
Instability; Back
Neuromuscular Electrical Stimulation and Motor Control
Phase I, this study aims to:- 1. Establish intra- and inter-rater reliability and minimal detectable change of ultrasound imaging measurement 2.
- Trial name
- NCT03786627
- Testing
- Combined NMES and motor control
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Central Spinal Cord Syndrome
Comparing Surgical Decompression Versus Conservative Treatment in Incomplete Spinal Cord Injury
Traumatic Central Cord Syndrome (TCCS) was until recent recognized as a separate clinical entity. The most characteristic feature is the disproportionate more motor impairment of the arms and especially the hands than the legs…
- Trial name
- COSMIC (NCT01367405)
- Testing
- Surgical decompression, Conservative treatment
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- Radboud University Medical Center
Scapular Dyskinesis, Posterior Shoulder Instability
Shoulder Pacemaker for Scapular Dyskinesia
The investigators purpose of this study is to determine patients-reported outcomes (VAS pain scores) in patients with Scapular Dyskinesis or Posterior Shoulder Instability who undergo rehabilitation with a shoulder pacemaker.
- Trial name
- NCT05116722
- Testing
- Shoulder Pacemaker
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
SPINAL Fracture, Burst Fracture
Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture
Treatment for acute traumatic thoracolumbar burst fractures differs significantly across the world in patients without neurological impairments and without damage to the posterior column of the spine.
- Conditions
- SPINAL Fracture, Burst Fracture, Spinal Instability of Thoracolumbar Region
- Trial name
- A34RCT (NCT05769114)
- Testing
- Surgical stabilization
- Where
- 2 sites in Switzerland
- Volunteers
- 52 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Shoulder Posterior Instability, Shoulder Anterior Instability
Evaluating Upper Limb Movement Precision With AuReha in People With One-Sided Motor Impairment
The clinical investigation is designed as a controlled, two-arm, intra-patient, non-randomized interventional study aimed at assessing the capabilities of the AuReha system in detecting upper limb movement precision in patients…
- Conditions
- Shoulder Posterior Instability, Shoulder Anterior Instability, Shoulder Anterior Latarjet Instability, Adhesive Capsulitis, Shoulder
- Trial name
- NCT07133100
- Testing
- Upper limb rehabilitation wearable device
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- DigitalRehab
Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLM
Asymmetric Lack of Knee Flexion as a Symptom of DLM in Children
Highlighted during the clinical examination of a knee flexion asymmetry, and related to the intraoperative meniscal observations on DLM. Search for a link between asymmetric bending defect and posterior shift in MCA-type DLM.
- Trial name
- NCT04741269
- Testing
- Find a link between lack of knee flexion and meniscal posterior luxation fixed
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Hospices Civils de Lyon
Spinal Instability
The Rehabilitation Outcome of Patients With Lumbar Spondylolisthesis. A Prospective Randomized Study
Patients with degenerative lumbar spondylolisthesis usually are present with low back pain, muscle spasm and weakness, radicular symptoms, intermittent claudication, insomnia, even urine or stool incontinence.
- Trial name
- NCT02435485
- Testing
- Biodex balance training, Rehabilitation including core spinal stabilization exercise
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Cervical Radiculopathy
Treatment of One and/or Two Level Cervical Degenerative Disc Disease
The objective of this study is to collect clinical and radiographic outcomes using the CONDUIT™ Interbody Cervical System with supplemental fixation using a DePuy Synthes Cervical Plating System.
- Trial name
- NCT05812092
- Testing
- CONDUIT Interbody Cervical System with DePuy Synthes Cervical Plating System
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Research Source
Sacroiliac; Fusion, Sacroiliac
Prospective SPINE Registry
This study is a prospective, multi-center, open label registry designed to collect real-world data on performance and safety data on RTI's spine products.
- Conditions
- Sacroiliac; Fusion, Sacroiliac, Joint Diseases, Musculoskeletal Diseases
- Trial name
- SPINE (NCT04176562)
- Testing
- RTI Spine products
- Where
- 12 sites in United States, Germany and 1 more
- Volunteers
- 5,000 people
- Sponsor
- Xtant Medical
Microsatellite Unstable Colorectal Cancer, Microsatellite Stable Colorectal Cancer
A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread
The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in meaningful tumor size reduction, in participants with colon cancer that has come back or has…
- Conditions
- Microsatellite Unstable Colorectal Cancer, Microsatellite Stable Colorectal Cancer, Mismatch Repair Proficient Colorectal Cancer, Mismatch Repair Deficient Colorectal Cancer
- Trial name
- CheckMate142 (NCT02060188)
- Testing
- Ipilimumab, Nivolumab, Cobimetinib
- Where
- 32 sites in United States, Australia and 6 more
- Volunteers
- 385 people
- Sponsor
- Bristol-Myers Squibb
Degenerative Disc Disease, Spondylolisthesis
Quintex® Follow-up After One Year Minimum
Prospective study, not randomised, non-interventional, monocentric, investigating an intended patient cohort of 60 patients already operated on the cervical spine due to degenerative disc disease of the cervical spine down to the…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Trauma, Spinal Stenosis
- Trial name
- Quintex (NCT04489394)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Low Back Pain
Recurrent Low Back Pain:Linking Mechanisms to Outcomes
The purpose of this study is to determine if trunk neuromuscular control strategies are changed by therapeutic exercises emphasizing core stabilization.
- Trial name
- NCT01085604
- Testing
- Core Stabilization
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Drexel University
SPINAL Fracture
Minimally Invasive Surgical Management of Traumatic Spinopelvic Instability
the main aim of this study is to evaluate the results of performing minimally invasive surgical management for cases with traumatic spinopelvic instability and spinopelvic dissociation.
- Trial name
- NCT05321186
- Testing
- minimally invasive spinopelvic fixation
- Volunteers
- 20 people
- Sponsor
- Assiut University
Degenerative Disc Disease, Cervical Spinal Instability
Cervical Interbody Implant Study
The primary objective of this study is to evaluate the safety and performance of cervical spine surgery using interbody implants as measured by reported complications, radiographic outcomes, and patient-reported outcomes (PROs).
- Trial name
- NCT04689854
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- NuVasive
Degenerative Osteoarthritis, Rheumatoid Arthritis
All Polyethylene Tibia-VEGA Kiel
Obligatory Post-Marketing Clinical Follow-up (PMCF) as part of the post marketing surveillance plan for the product under investigation For this PMCF only CE-marked medical devices will be used within their intended purpose and…
- Conditions
- Degenerative Osteoarthritis, Rheumatoid Arthritis, Post-traumatic; Arthrosis, Other Instability, Knee
- Trial name
- APT-VEGA_KI (NCT02756702)
- Testing
- All-Poly
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Aesculap AG