Clinical trials: Back Pain
Low Back Pain, Leg Pain
Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis
The purpose of this multi-center, randomized, clinical study is to establish the safety and effectiveness of the TOPS™ System, used following decompression, in the treatment of lower back and leg pain with, or without spinal…
- Conditions
- Low Back Pain, Leg Pain, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT00405691
- Testing
- "TOPS System" - Total Posterior Arthroplasty Implant
- Where
- 16 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Impliant, Ltd.
Low Back Pain
Non-Specific Chronic Back Pain; Insight From Spatial Aspects of Lumbar Spinal Muscle Activation
There is evidence for altered muscle activity patterns in individuals with non-specific chronic back pain (NSCBP). It is unknown why these alterations in activation pattern occur and how they may be linked to pain experience and…
- Trial name
- NCT01214213
- Where
- Norway
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Groin Strain
Effects of Active Tissue Release Techniques on Groin Pain in 2nd Trimester of Pregnancy
The study will focus on the effects of active tissue release techniques on groin pain, hip range of motion, and functional disability in 2nd trimester of pregnancy.
- Trial name
- NCT06340126
- Testing
- Active release techniques, Relaxation exercises
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Low Back Pain
Comparison of Spinal Kinematics Between Asymptomatic Subjects and Patients With Low Back Pain
Low back pain (LBP) is a complex and common problem with major societal repercussions. Clinical evaluations, and especially functional assessments, are necessary for proper diagnosis and decisions on the most appropriate…
- Trial name
- NCT02278549
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Haute Ecole de Santé Vaud
Low Back Pain
Effects of Kinesiotaping and Electrical Muscle Stimulation on Low Back Pain and Disability
To compare the effects of kinesiotaping and electrical muscle stimulation on low back pain and disability associated with diastasis recti.
- Trial name
- NCT05834153
- Testing
- kinesiotaping, electrical muscle stimulation
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Pain, Low Back Pain
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
The purpose of this study is to investigate, in two phases: (1) the feasibility and safety of Virtual Embodiment Therapy in treating chronic pain of lower back and upper limbs and (2) the efficacy of Virtual Embodiment Therapy on…
- Conditions
- Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction
- Trial name
- NCT04060875
- Testing
- Karuna Labs Virtual Reality Software
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Low Back Pain
Effectiveness of the SelfBack-App in Preventing and Treating Low Back Pain Versus no Intervention: a Non-randomized Clinical Trial
Low back pain (LBP) is the leading cause of disability worldwide and represents a major burden for both individuals and healthcare systems.
- Trial name
- NCT07785804
- Testing
- Selfback app, No Interventions
- Where
- Belgium
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Low Back Pain
Pain Sensory Profile Changes Following Treatment of Chronic Low Back Pain
Several cross-sectional studies have demonstrated that patients with chronic low back pain have higher levels of pain sensitivity (local and widespread) when compared to controls.
- Trial name
- LBP (NCT03748849)
- Testing
- Physiotherapy
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Chronic Low-back Pain
Swimming Versus Standard Physiotherapy Care as Rehabilitation Modalities for Persistent Low Back Pain: Feasibility Study
Study four: A small scale RCT will be conducted to pilot the swimming lessons developed in study three, to compare the lessons to standard physiotherapy care and to assess the feasibility of conducting a large RCT in the future.
- Trial name
- NCT06423755
- Testing
- Swimming programme, Standard Physiotherapy care
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Post Herpetic Neuralgia, Pain
A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.
This study is a 3-part, Double-blind, Randomized, Placebo-controlled, Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics/Pharmacodynamic properties of iN1011-N17 after Oral Administration in Healthy…
- Conditions
- Post Herpetic Neuralgia, Pain, Osteoarthritis, Neuropathic Pain
- Trial name
- NCT06218784
- Testing
- iN1011-N17 HCl Suspension (Part 1), iN1011-N17 HCl Capsule (Part 1), iN1011-N17 HCl Capsule (Part 2)
- Where
- Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- iN Therapeutics Co., Ltd.
Pain, Back
Effects of Global Postural Re-education Versus Laser-guided Exercise in Non-specific Chronic Low Back Pain
Effects of Global Postural Re-education Versus Laser-guided Supervised Exercise in Individuals With Non-specific Chronic Low Back Pain
- Trial name
- NCT06430255
- Testing
- Global Postural Re-education, Laser-guided Supervised Exercise
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taif University
Pain, Pain, Chronic
Transitioning to a Valve -Gated Intrathecal Drug Delivery System
This study is designed to explore if the valve-gated pump requires less drug to manage subject pain than the prior standard peristaltic pump in the same subject.
- Conditions
- Pain, Pain, Chronic, Pain, Intractable, Pain, Back
- Trial name
- TRANSIT (NCT04312685)
- Testing
- Prometra II Programmable Pump system - Flowonix Medical
- Where
- 8 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bux, Anjum, MD
Back Pain
the Hypoalgesic Effect of Spinal Manual Therapy
To study the immediate effect of spinal manual therapy on pain perception in normal subjects
- Trial name
- NCT01869140
- Testing
- spinal manual therapy
- Where
- Australia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institut Franco Europeen de Chiropratique
Back Pain
Cytology Study of Cells From Patients With Low Back Pain
The investigators are doing this study to learn more about the cause of back pain with or without pain shooting down one or both legs.
- Trial name
- NCT01089478
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Low Back Pain, Pelvic Pain
Generalized Versus Core Stabilization Antenatal Exercises For Lumbopelvic Pain
Core stability training has gained popularity as a fitness trend and is now being used in rehabilitation programs as well the patient adherence to this intervention has been low due to its complex nature, particularly pregnant…
- Trial name
- NCT06303258
- Testing
- Core Stabalization Exercises, Generalized Antenatal Exercises
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Musculoskeletal Disorders, Neck Pain
Evaluation of Ergonomic Risks and the Effect of Patient Education on Musculoskeletal Complaints, Posture and Breathing Awareness in Bank Employees
This study aims to evaluate ergonomic risks among bank office employees and to investigate the effects of patient education and breathing exercises on musculoskeletal complaints, posture, ergonomic awareness and breathing…
- Conditions
- Musculoskeletal Disorders, Neck Pain, Low Back Pain, Postural Problems
- Trial name
- NCT07481838
- Testing
- Ergonomic Education
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Chronic Pain, Low Back Pain
Embodiment in Virtual Reality as a Telemedicine Digital Therapeutic for the Treatment of Chronic Shoulder Pain
Chronic shoulder pain is a common musculoskeletal pain condition that can have a profound impact on a sufferer's life and a large socioeconomic healthcare burden to society.
- Conditions
- Chronic Pain, Low Back Pain, Shoulder Pain
- Trial name
- NCT05375500
- Testing
- telemedicine digital therapeutic
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Intervertebral Disc Degeneration, Back Pain
Tissue Collection for Understanding Intervertebral Disc Degeneration and Back Pain
The purpose of the research is to collect and examine spinal disc and ligament tissues to see if there are any biological markers that can be correlated with MRI images to help us learn more about causes of back pain.
- Trial name
- NCT01633034
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Low Back Pain
Evaluating Acupuncture Relationship With the Catecholaminergic Pathway
Activation of the sympathetic nervous system attenuates inflammation via catecholamines, recent advances in electroacupuncture allow activating critical neuronal networks with the release of catecholamines the aim of this…
- Trial name
- NCT02876432
- Testing
- Electroacupuncture, Diclofenac sodium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Low Back Pain
Predicting Patients' Response to Spinal Manipulation
The purpose of this study is to compare the clinical effectiveness of two types of chiropractic spinal manipulation to conservative medical care for patients at least 55 years old with sub-acute or chronic LBP.
- Trial name
- NCT00285649
- Testing
- HVLA-SM, LVVA-SM, Usual Medical Care
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Palmer College of Chiropractic