Clinical trials: Back Pain Lower Back
Degenerative Disc Disease, Intervertebral Disc Disease
Treatment of Degenerative Disc Disease With Allogenic Mesenchymal Stem Cells (MSV)
In this study we want to evaluate the clinical use of allogenic mesenchymal stem cells (MSC), obtained from bone marrow of healthy donors, for treatment of Degenerative Disc Disease (DDD).
- Conditions
- Degenerative Disc Disease, Intervertebral Disc Disease, Low Back Pain
- Trial name
- Disc_allo (NCT01860417)
- Testing
- Allogenic Mesenchymal Stromal Cells, Mepivacaine
- Where
- 2 sites in Spain
- Volunteers
- 24 people
- Sponsor
- Red de Terapia Celular
Low Back Pain
Wallis Stabilization System for Low Back Pain
The purpose of this study is to demonstrate that the Wallis System (interspinous process implant) is equivalent to total disc replacement (TDR) for the treatment of mild to moderate degenerative disc disease (DDD) of the lumbar…
- Trial name
- NCT00484458
- Testing
- Interspinous process and dynamic stabilization (Wallis System), Total Disc Replacement
- Where
- 11 sites in United States
- Volunteers
- 340 people
- Sponsor
- Zimmer Spine
Low-Back Pain
PROs in Chronic Low Back Pain Patients With Accompanying Lower Limb Pain (Neuropathic Component) Treated With Pregabalin
The purpose of this study is to evaluate the effect of pregabalin comparing with the conventional analgesic care in chronic low back pain patients with accompanying lower limb pain (neuropathic component) treated in primary care…
- Trial name
- PRO (NCT02273908)
- Testing
- No intervention
- Where
- 33 sites in Japan
- Volunteers
- 331 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Low Back Pain
Effect of the LumbaCure® Intervention on Elderly Patients Suffering From cLBP.
The goal of this investigation is to evaluate the safety and efficacy of the LumbaCure® device in elderly people suffering from low back pain.
- Trial name
- LumbaCure2303 (NCT06203886)
- Testing
- LumbaCure
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Odix
Acute Low-back Pain
Efficacy and Safety of Etoricoxib/Cyanocobalamin Versus Etoricoxib for Acute Low Back Pain
Phase III longitudinal, multicenter, randomized, double-blind clinical trial. The aim of this study is to evaluate the efficacy and safety of the Fixed-Dose Combination of Etoricoxib/Cyanocobalamin Versus Etoricoxib in Patients…
- Trial name
- NCT06517823
- Testing
- Etoricoxib + Cyanocobalamin fixed dose, Etoricoxib fixed dose
- Where
- Mexico
- Volunteers
- 190 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Chronic Lower Back Pain (CLBP), SIJ Arthropathy
Endoscopic Electrothermic Procedure of the Sacroiliac Joint
1. Determine the rate and incidence of peri-operative \& post-operative adverse events (complications, infections, re-operations, re-admissions) in the endoscopic approach for the treatment of SIJ arthropathy and chronic lower…
- Trial name
- ESIJ (NCT03920345)
- Testing
- MultiZYTE
- Where
- 3 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- joimax, Inc.
Chronic Low Back Pain
The Effects of the MME Procedure on Chronic Low Back Pain
The purpose of this study is to test whether or not the Magnetic Molecular Energizer (MME) device provides a well tolerated and effective intervention to reduce pain, pain-related symptoms and improve ability to function in those…
- Trial name
- NCT00325377
- Testing
- MME Procedure
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Advanced Magnetic Research Institute International
Chronic Low Back Pain
Pilot Study of the Efficacy and Safety of Lidoderm Patch in the Treatment of Low Back Pain
Patients with moderate to severe chronic Low Back Pain (LBP) despite current analgesic treatment participated in a Phase IV clinical trial to evaluate the analgesic efficacy of the lidocaine patch 5% compared to placebo in…
- Trial name
- NCT00904475
- Testing
- Lidoderm®
- Where
- 6 sites in United States
- Volunteers
- 102 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Gastric Ulcer, Duodenal Ulcer
Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer
The purpose of this study is to assess the Safety and tolerability of D961H (Esomeprazole) 20 mg once daily for up to 52 weeks of treatment involving patients with a history of gastric and/or duodenal ulcers receiving daily…
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- NCT00595517
- Testing
- Esomeprazole 20 mg
- Where
- 3 sites in Japan
- Volunteers
- 395 people
- Sponsor
- AstraZeneca
Low Back Pain
Analgecine for Treatment of Low Back Pain
The study examines the efficacy and safety of Analgecine in the treatment of chronic pain in patients with low back pain for 3 months after surgical treatment.
- Trial name
- NCT02168010
- Testing
- Analgecine, Neurotropin
- Where
- 7 sites in China
- Volunteers
- 584 people
- Sponsor
- VanWorld Pharmaceutical (Rugao) Company Limited
Low Back Pain
Efficacy and Safety of Lymphdiaral Basistropfen (HDC) in the Treatment of Chronic Low-back Pain
To evaluate superiority of HDC in comparison to placebo in the treatment of chronic low-back pain in relation to pain, functional impairment, quality of life, and state of health during a 15-week treatment period.
- Trial name
- 144 (NCT01049373)
- Testing
- HDC
- Where
- Germany
- Volunteers
- 221 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Back Pain, Chronic Pain
Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode
The primary objective of this study is to evaluate the acute and chronic efficacy of spinal cord stimulation using the Precision implantable neurostimulation device with the Artisan paddle electrode in patients with Failed Back…
- Conditions
- Back Pain, Chronic Pain, Pain in Leg, Unspecified
- Trial name
- NCT00386724
- Testing
- Precision Spinal Cord Stimulation System, Artisan Surgical Lead
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Boston Scientific Corporation
Low Back Pain
Safety and Efficacy Study of an Etoricoxib and Tizanidine Fixed Dose Combination in Participants With Moderate to Severe Acute Low Back Pain (MK-0663B-164)
The primary objective of this study is to evaluate the safety and tolerability of MK-0663B (etoricoxib/tizanidine) among participants with moderate-to-severe acute low back pain.
- Trial name
- NCT01979510
- Testing
- MK-0663B, DOLOCAM PLUS®, Acetaminophen 500 mg
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Low Back Pain, Osteoarthritis
Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee
The primary objective of the study is to evaluate the efficacy of fasinumab in relieving Chronic low back pain (CLBP) as compared to placebo in participants with a clinical diagnosis of moderate-to-severe non-radicular CLBP and…
- Trial name
- FACT CLBP 1 (NCT03285646)
- Testing
- Fasinumab
- Where
- 56 sites in United States
- Volunteers
- 63 people
- Sponsor
- Regeneron Pharmaceuticals
Lower Back Pain
A Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back
The purpose of this study is to determine if two sustained released formulations of carisoprodol are more effective than placebo.
- Trial name
- NCT00671502
- Testing
- Carisoprodol SR
- Where
- 68 sites in United States
- Volunteers
- 840 people
- Sponsor
- Meda Pharmaceuticals
Chronic Osteoarthritis Pain, Chronic Low Back Pain
Study of PIPE-791 for Subjects With Chronic Osteoarthritis Pain or Chronic Low Back Pain
The primary goal of this clinical trial is to learn if PIPE-791 is safe and well-tolerated in adults with chronic osteoarthritis pain (COAP) or chronic low back pain (CLBP).
- Trial name
- NCT06810245
- Testing
- PIPE-791
- Where
- 5 sites in United States
- Volunteers
- 43 people
- Sponsor
- Contineum Therapeutics
Opioid Use, Low Back Pain
Impact of DuoTherm on Opioid Use and Low Back Pain
Evaluate the difference in opioid use, pain intensity and pain interference in patients with moderate to severe low back pain using DuoTherm multimodal harmonic mechanical stimulation (M-Stim) unit compared to Transcutaneous…
- Trial name
- NCT04491175
- Testing
- M-Stim, TENS
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- MMJ Labs LLC
Chronic Low Back Pain, Leg Pain
MIS MiLIF Versus Open
This study is being undertaken to compare the clinical outcomes of patients that have unilateral posterolateral lumbar interbody fusion using a traditional open approach versus the MiLIF procedure based on the MiCOR Precision…
- Trial name
- NCT00792129
- Testing
- The Atavi System
- Where
- 9 sites in United States
- Volunteers
- 113 people
- Sponsor
- Zimmer Biomet
Back Pain
Comparison of Intraspinal Nerve Root Stimulation With Dorsal Column Stimulation
This study will systematically evaluate the programming parameters of the Precision Spinal Cord Stimulation Device to optimally relieve pain while minimizing any uncomfortable side effects.
- Trial name
- NCT00370773
- Testing
- Precision Spinal Cord Stimulation System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Scientific Corporation
Low Back Pain
Efficacy Safety of a Combination Thiocolchicoside+Ketoprofen Compared to Thiocolchicoside Twice a Day for 7 Days in Patients Suffering From Acute Non Specific Low Back Pain
Primary Objective : To demonstrate the superiority of the oral fixed - combination of a muscle relaxant, thiocolchicoside (TCC) to a non steroidal anti-inflammatory drug, ketoprofen, over oral TCC, on average pain within the last…
- Trial name
- TIOKET (NCT00679146)
- Testing
- Thiocolchicoside+Ketoprofen, Thiocolchicoside
- Where
- 6 sites in Brazil, Colombia and 4 more
- Volunteers
- 334 people
- Sponsor
- Sanofi