Clinical trials: Back Pain Lower Back
Low Back Pain, Neck Pain
Electrical Impedance Myography of Neck and Low Back Pain
The purpose of this study is to assess neck and low back pain using Electrical Impedance Myography (EIM) in order to develop an algorithm to aid primary care providers (PCPs) in the diagnosis of neck/back pain.
- Trial name
- EIM (NCT02159677)
- Testing
- EIM Measurements
- Where
- 2 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Skulpt, Inc.
Low Back Pain
Safety And Efficacy Of Celecoxib Versus Sodium Diclofenac In The Treatment Of Acute Low Back Pain
To evaluate the safety and efficacy of celecoxib versus sodium diclofenac in subjects with acute low back pain
- Trial name
- NCT00640432
- Testing
- Diclofenac, Celecoxib
- Where
- 9 sites in Brazil
- Volunteers
- 244 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Low Back Pain
A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
The primary objective is to assess the efficacy of oxycodone/naloxone controlled-release tablets (OXN) for the management of opioid-induced constipation (OIC) compared with oxycodone controlled-release tablets (OXY) in subjects…
- Trial name
- NCT01427283
- Testing
- Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release
- Where
- 149 sites in United States
- Volunteers
- 450 people
- Sponsor
- Purdue Pharma LP
Lower Back Pain
Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back
The purpose of this study is to determine if two sustained released formulations of carisoprodol are more effective than placebo.
- Trial name
- NCT00671879
- Testing
- Carisoprodol SR 700 mg, Carisoprodol SR 500 mg
- Where
- 73 sites in United States
- Volunteers
- 830 people
- Sponsor
- Meda Pharmaceuticals
Low Back Pain
Safety, Effectiveness, and Impact on Quality of Life on Long-Term Administration of OROS Hydromorphone Slow-Release in Patients With Chronic Low Back Pain
The purpose of this open-label, extension study is to characterize the safety, effectiveness, and impact on quality of life measures of long-term repeated dosing of OROS hydromorphone slow release (8, 16, 32 and 64 mg tablets) in…
- Trial name
- NCT00411268
- Testing
- OROS hydromorphone HCI SR (slow release)
- Volunteers
- 207 people
- Sponsor
- Alza Corporation, DE, USA
Chronic Low Back Pain
Cytochrome P450 Pharmacokinetic DDIs Among Patients With Chronic Low Back Pain Taking Opioids
Using a retrospective analysis of a large commercial claims database and a Medicare database, the investigators evaluated DDEs that have the potential to cause DDIs among chronic low back pain (cLBP) patients on long-term opioid…
- Trial name
- NCT01177241
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- NEMA Research, Inc.
Chronic Low Back Pain
A Double Blind Placebo Study to Determine the Effectiveness of Theramine on the Management of Chronic Back Pain
This research protocol will compare Theramine to a non-steroidal anti-inflammatory drug (NSAID) in the treatment of chronic back pain.
- Trial name
- NCT01490905
- Testing
- Theramine (A medical food), Theraprofen, Ibuprofen
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Targeted Medical Pharma
Low Back Pain
Assessing the Impact of the Axomove Therapy Medical Device on Low Back Pain Patients
An evaluation study of the impact of the Axomove Therapy® medical device on subacute or chronic low back pain patients leaving rehabilitation centres to facilitate self-rehabilitation.
- Trial name
- AVA-PREPA (NCT05910463)
- Testing
- AXOMOVE Therapy Medical Device
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Axomove
Chronic Low-back Pain
Personalized Auricular Vagus Nerve Stimulation in Intractable Chronic Low Back Pain
One in five people in the general adult population suffer from chronic pain, a figure that is higher than heart disease, cancer, and diabetes combined. A majority of these patients is suffering from chronic back pain.
- Trial name
- AuriMod (NCT04753528)
- Testing
- AuriMod CT01_A, AuriMod CT01_B, AuriMod CT01_C
- Where
- 2 sites in Austria, Switzerland
- Volunteers
- 43 people
- Sponsor
- Aurimod GmbH
Low Back Pain
A Trial Comparing Three Orthobiologic Therapies on Atrophied Multifidus Muscles in Patients With Low Back Pain
To evaluate and compare the effectiveness of 3 different injection treatments on multifidus atrophy and lower back pain.
- Trial name
- NCT03618979
- Testing
- PPP treatment, PRP treatment, PRP and PL Combo treatment
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Regenexx, LLC
Chronic Non-specific Low Back Pain
Comparison of VER-01 to Opioids in Patients With Chronic Non-specific Low Back Pain
Randomized, open-label, parallel-group phase III trial to prove an additional benefit of the full-spectrum cannabis extract VER-01 over opioids in patients with chronic non-specific low back pain for whom drug treatment is…
- Trial name
- ELEVATE (NCT05610813)
- Testing
- VER-01, Opioid therapy
- Where
- 2 sites in Germany
- Volunteers
- 384 people
- Sponsor
- Vertanical GmbH
Low Back Pain
Efficacy and Safety of ARTRA (Glucosamine Plus Chondroitin Sulfate Combination) in Treatment of Chronic Low Back Pain
To study the safety and efficacy of ARTRA (glucosamine chondroitin sulfate) in the treatment of non-specific low-back pain of lumbosacral localization in ambulatory care.
- Trial name
- NCT01990729
- Testing
- ARTRA
- Where
- Russia
- Volunteers
- 10,000 people
- Sponsor
- Unipharm, Inc.
Low Back Pain, Shoulder Pain
An Efficacy and Safety Study of Tramadol Hydrochloride-Paracetamol in Treatment of Moderate to Severe Acute Neck-Shoulder Pain and Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of tramadol hydrochloride-paracetamol tablets in treatment of moderate (medium level of seriousness) to severe (very serious) acute neck, shoulder and low back pain…
- Conditions
- Low Back Pain, Shoulder Pain, Neck Pain
- Trial name
- NCT01843660
- Testing
- Tramadol HCl-Paracetamol
- Volunteers
- 1,059 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Chronic Low Back Pain
Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
The primary purpose of the study was to test the efficacy of 2 tablets (twice daily) of ABT-712, compared to placebo, administered over a 4-week period in participants with moderate to severe mechanical chronic low back pain…
- Trial name
- NCT00761150
- Testing
- ABT-712
- Where
- 32 sites in United States
- Volunteers
- 308 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Lumbar Degenerative Disc Disease, Lower Back Pain
Human Autograft Mesenchymal Stem Cell Mediated Stabilization of The Degenerative Lumbar Spine
Investigate the potential of tissue grafting that includes human mesenchymal stem cells in the repair and potential stabilization of the degenerative Lumbar disk and facet joint denovo and at the time of surgical reconstruction.
- Conditions
- Lumbar Degenerative Disc Disease, Lower Back Pain, Chronic Lower Back Pain
- Trial name
- NCT02529566
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Foundation for Spinal Research, Education and Humanitarian Care, Inc.
Low Back Pain
Effects of Programming Parameters on Back Pain Relief in Subthreshold Spinal Cord Stimulation
The purpose of this study is to investigate the effects of varying programming parameters in subthreshold spinal cord stimulation therapy for pain relief.
- Trial name
- NCT01550562
- Testing
- Boston Scientific Precision Plus spinal cord stimulation therapy
- Where
- Australia
- Volunteers
- 1 people
- Sponsor
- Boston Scientific Corporation
Discogenic Pain
Study Investigating STA363 Compared to Placebo in Patients With Chronic Discogenic Low Back Pain
This is a phase IIb, prospective, multi-country, multicenter, randomized, double-blind, placebo-controlled, parallel group study to investigate the efficacy, safety and transformation of NP following single intradiscal injection…
- Trial name
- STA-02 (NCT04673461)
- Testing
- STA363 containing 90 mg (60 mg/mL) lactic acid, STA363 containing 180 mg (120 mg/mL) lactic acid
- Where
- 17 sites in Netherlands, Russia and 1 more
- Volunteers
- 110 people
- Sponsor
- Stayble Therapeutics
Low Back Pain
A Study on Efficacy (Effectiveness), Safety, and Impact on Quality of Life Measures of Dilaudid CR (Controlled Release);, Hydromorphone HCl in Patients With Chronic Low Back Pain
The purpose of the study was to characterize the safety, effectiveness, and impact on quality of life (QOL) measures of OROS® hydromorphone HCL in patients with chronic low back pain.
- Trial name
- NCT00398788
- Testing
- OROS® hydromorphone HCL; Dilaudid CR (controlled release); Dilaudid IR (immediate release) as rescue medicine
- Volunteers
- 207 people
- Sponsor
- Alza Corporation, DE, USA
Chronic Low-back Pain, Degenerative Disc Disease
Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain
The brief purpose of this research study is to learn about the safety, tolerability, and efficacy of paraspinal intramuscular injection of CELZ-201-DDT in patients with chronic lower back pain.
- Trial name
- ADAPT (NCT06053242)
- Testing
- CELZ-201-DDT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Creative Medical Technology Holdings Inc
Low Back Pain
dorsaVi Back Pain and Movement Registry
This study will compare patients with low back pain (LBP) to age and gender matched controls to determine if there are differences between the two groups related to: range of movement, secondary outcomes (level of disability…
- Trial name
- BPAM (NCT03001037)
- Where
- 3 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- dorsaVi Ltd