Clinical trials: Bacterial Contamination
Nosocomial Infections
Potential Nosocomial Infection Prevention Via Modification of Anesthesia Intraoperative Aseptic Practice
We hypothesized that by improving hand hygiene compliance in the operative environment, we would reduce horizontal transmission of pathogenic bacteria to surgical patients.
- Trial name
- NCT00617006
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Bacterium-Related Malignant Neoplasm
Peritoneal Bacterial Contamination Following Resection With Closed or Open Rectal Stump for Left-sided Cancer
The purpose of this study is to check if there is a difference in peritoneal contamination in patients undergoing rectal resection with closed and open rectal stump prior to anastomosing.
- Trial name
- NCT02527382
- Testing
- Closed stump
- Volunteers
- 26 people
- Sponsor
- Florin Iordache
Cross Infection, Infection Control
A Randomized Trial Comparing Matt and Antimicrobial Cellomed Laminates
Sepsis contributes to nearly 20% of all hospital deaths and is the leading cause of death on non-coronary intensive care units. Contamination of the patient environment is common with organisms such as MRSA, VRE and C.difficile…
- Trial name
- NCT01245829
- Testing
- Swabbing of observation chart
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- County Durham and Darlington NHS Foundation Trust
Reduction in Bacterial Counts Through the Use of Mouthwash
Dental Implants and Mouth Rinse
The primary aim of this study is to evaluate and compare the efficacy of a 60 second rinse with chlorhexidine, essential oil-based mouthwash, cetylpyridinium chloride mouthwash, or saline solution on bacterial contamination in…
- Trial name
- NCT02002442
- Testing
- Mouthwash
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tufts University
Catheter Infection
Local Inflammation Does Not Correlate With Bacterial Colonization and Contamination of Perineural Catheters
The aim of this study was to investigate the influence of alcoholic skin disin-fection before PNC (perineural catheter)-removal on the detection of bacteria on the subcutaneous part of the PNC or on the tip.
- Trial name
- NCT02599181
- Testing
- propanol-biphenol: Kodan
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Bacterial Contamination of Healthcare Worker Uniforms
Bacterial Contamination of Healthcare Worker Uniforms
Healthcare worker uniforms are frequently contaminated with bacteria known to cause infections in humans. These bacteria are acquired during the workday.
- Trial name
- NCT01537835
- Testing
- Antimicrobial Scrubs
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Bacterial Contamination
Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols
This clinical trial evaluates the effectiveness of pre-procedural mouthwashes in reducing bacterial contamination in dental aerosols generated during ultrasonic scaling.
- Trial name
- NCT07880509
- Testing
- 0.09% CPC + Zinc Lactate Mouthwash, 0.2% Chlorhexidine Mouthwash, Water
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Contamination of the Handles, Quality of the Laryngoscopy
Comparison of Two Laryngoscopes: Single-use Device Laryngobloc ® (SU) Versus Reusable Handle With Disposable Metal Blade (R)
Reduce the risk of nosocomial transmission of germs related to the reusability of the laryngoscope handle. The alternative is to replace it with a disposable device, provided that it is as effective as the reference strategy at a…
- Trial name
- MUUR (NCT01632085)
- Testing
- The two groups SU and R are defined by the device with which intubation is performed after a first laryngoscopy done with the other device.
- Where
- France
- Volunteers
- 480 people
- Sponsor
- University Hospital, Strasbourg, France
Drug Contamination
Evaluation of Bacterial and Fungal Contamination During Propofol Continuous Infusion
The purpose of this study is to verify the existence of bacterial and/or fungal contamination during different technics of propofol with or without EDTA continuous infusion in patients undergoing general anesthesia.
- Trial name
- NCT00757458
- Testing
- EDTA without re-filling, Propofol syringe re-filling with propofol containing EDTA, Target controlled infusion of propofol without EDTA
- Where
- Brazil
- Volunteers
- 652 people
- Sponsor
- University of Sao Paulo
Surgical Site Infection (SSI), Spine Surgery
Investigation of the PREVENTIA® Irrigation Solution for Reducing Bacteria in Spinal Surgery With Implants - A Comparative Study
Spinal surgery carries a risk of surgical wound infections (i.e., the entry of bacteria). Despite various preventive measures, such infections continue to occur, particularly in operations involving implants.
- Conditions
- Surgical Site Infection (SSI), Spine Surgery, Surgical Site Infection Prevention
- Trial name
- PROTECT-SPINE (NCT07667036)
- Testing
- Preventia Surgical Solution, 0.9 % NaCl
- Where
- Switzerland
- Volunteers
- 114 people
- Sponsor
- Universität Luzern
Clostridium Difficile Infection
Does Fidaxomicin Therapy Reduce Spread of Clostridium Difficile?
This study evaluates whether patients with Clostridium difficile infection (CDI) who are treated with fidaxomicin have less contamination of their skin and surrounding environment with spores of C.
- Trial name
- NCT02461901
- Testing
- Environmental sampling, Skin swab sampling, Fecal sampling
- Where
- 3 sites in United Kingdom
- Volunteers
- 203 people
- Sponsor
- Professor Mark Wilcox
Bacteremia
Efficacy of 2% Chlorhexidine Gluconate in 70% Alcohol Compare 10% Povidone Iodine in Blood Culture in Children
To evaluate the efficacy of 2% chlorhexidine gluconate in 70% alcohol compared with 10% povidone iodine in reducing blood culture contamination in pediatric patients.
- Trial name
- NCT01919593
- Testing
- 2% chlorhexidine gluconate in 70% alcohol, 10%povidone iodine
- Where
- Thailand
- Volunteers
- 1,269 people
- Sponsor
- Thammasat University
to Evaluate Antimicrobial Effect of Eco-friendly Toothbrush
Evaluation of Bacterial Contamination and Antimicrobial Efficacy on Charcoal-Infused vs, Standard Nylon Toothbrush Bristles.
This study compares two types of toothbrushes to see which one stays cleaner after use. Researchers want to know if toothbrushes with charcoal-infused bristles have fewer bacteria than standard toothbrushes with nylon bristles.
- Trial name
- NCT07365748
- Testing
- Eco-friendly toothbrush for children, nylon bristles toothbrush in children, Nylon bristles toothbrush in adults
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MTI University
Health Care Workers, Including Physicians, Nurses, and Nursing Aids
Prevalence of Bacterial Contamination on Smart Cell Phone vs. Non-smart Phone
Using smartphone is increasing in hospital with various purpose and it has more extended surface than non-smart phone. Therefore investigators can consider the bacterial contamination rate of smartphone will be higher than that…
- Trial name
- NCT01347502
- Where
- 3 sites in South Korea
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Bacteremia
A Cluster-randomized Cross-over Trial Evaluating the Comparative Effectiveness of Three Skin Antiseptic Interventions
Background: Contaminated blood cultures result in unnecessary antibiotic use, increased length of stay, and additional laboratory tests, all of which increase healthcare costs.
- Trial name
- NCT01216761
- Testing
- Iodine tincture, Chlorhexidine gluconate, Povidone iodine
- Volunteers
- 3,879 people
- Sponsor
- University of Michigan
Efficacy of Hand Hygiene Protocols
Efficacy of Alcohol Hand-rubbing Covering All Hand Surfaces in Reducing Bacterial Hand Contamination of Healthcare Staff
This is a randomized controlled trial comparing the effectiveness of three hand hygiene protocols, during routine inpatient clinical care: Protocol 1: handrubbing with alcohol covering all hand surfaces in no particular order…
- Trial name
- B/07/310 (NCT01337856)
- Testing
- Hand hygiene protocol
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Infection, Bacterial, Wound Infection
DACC in the REduction of Surgical Site INfection
Surgical site infection is an infection at a place in the body where surgery has taken place, and has been reported in around 5% of people undergoing an operation. In vascular surgery, infection rates are as high as 30%.
- Conditions
- Infection, Bacterial, Wound Infection, Wound Infection, Surgical, Surgical Incision
- Trial name
- DRESSINg (NCT02992951)
- Testing
- DACC-Coated Post Operative Dressing
- Where
- United Kingdom
- Volunteers
- 722 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Antibiotic Resistance, Extended-spectrum Betalactamase
Assessment of the Prevalence of Extended-Spectrum Betalactamase Producing Enterobacteriaceae Among ICU Staff
Evaluation of the prevalence of ESBL-Enterobacteriaceae colonization among ICU staff
- Conditions
- Antibiotic Resistance, Extended-spectrum Betalactamase, Enterobacteriaceae, Escherichia Coli
- Trial name
- REASSE (NCT02367339)
- Testing
- ESBL
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pressure Ulcers
Silk-Like Fabric for the Prevention of Pressure Sores in a Long Term Care Setting
The primary purpose of this research study is to evaluate if DermaTherapy® bedding will significantly reduce pressure ulcer incidence by decreasing maceration, friction, and shearing among residents of Nursing Homes.
- Trial name
- NCT01355666
- Testing
- DermaTherapy® Linen and underpads.
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Precision Fabrics Group, Inc.