Clinical trials: Bariatric Surgeries
Obesity, Obesity Recidivism
Financial Incentives and Weight Loss in Failed Bariatric Surgery
This national, prospective, multicenter, and randomized study seeks to evaluate the effect of financial incentives on weight loss in individuals who experience weight regain following bariatric surgery.
- Trial name
- BARIACADO (NCT06910735)
- Testing
- Control, Threshold financial incentive, Proportional financial incentive
- Where
- 12 sites in France
- Volunteers
- 264 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity
Chest Physiotherapy After Bariatric Aurgery - A Comparison Between Incentive Spirometry and Expiratory Positive Airway Pressure (Epap)
Objective: To compare the effects of the EPAP and the incentive spirometry flow-oriented in the pulmonary function after bariatric surgery.
- Trial name
- NCT00678678
- Testing
- Incentive Spirometry - RESPIRON, Kit Epap®:
- Where
- Brazil
- Sponsor
- Universidade Metodista de Piracicaba
Postoperative Pain Relief
Bilateral Thorathic Erector Spinae Plane Block in Laparoscopic Bariatic Surgeries
The study is to evaluate effectiveness of one-level versus two-level thoracic ESP block on intraoperative and postoperative analgesia in bariatric surgeries and to compare total opioid consumption of both groups.
- Trial name
- ESPBbariatrics (NCT06812364)
- Testing
- one level ESPB, two level ESPB
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Sleeve Gastrectomy
Crural Dissection in Sleeve Gastrectomy
The purpose of this study is to identify if there is a benefit in routine dissection of the diaphragmatic crura during sleeve gastrectomy.
- Trial name
- NCT04168060
- Testing
- Crura dissection, Sleeve gastrectomy, Hiatal hernia repair
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Miami
Obesity, Obesity (Disorder)
Quality of Recovery and Patient Satisfaction After Metabolic Surgery at a Tertiary Hospital in Gauteng (QoRPS-MS)
PURPOSE OF THE STUDY?This study aims to assess patients' quality of recovery and satisfaction after metabolic surgery at a tertiary hospital in South Africa using two validated questionnaires.
- Conditions
- Obesity, Obesity (Disorder), Metabolic Disease
- Trial name
- QoRPS-MS (NCT07804290)
- Where
- South Africa
- Volunteers
- 84 people
- Sponsor
- Sefako Makgatho Health Sciences University
Postoperative Nausea and Vomiting
Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting
The investigators want to test if it is indicated to associate dexamethasone and ondansetron in obese patients having bariatric surgery under total intra-venous closed-loop anesthesia.
- Trial name
- Loop-NVPO (NCT01876290)
- Testing
- Dexamethasone and Ondansetron
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Hopital Foch
Obesity
Metabolic Impact of Dietary Protein Supplementation in Surgical Weight Loss
The obesity epidemic has grown rapidly in the United States, and is associated with increased morbidity and mortality rates. Bariatric surgery (BS) has emerged as the most effective treatment for severe obesity.
- Trial name
- MIPS (NCT02269410)
- Testing
- GBP-SPS, GBP-HPS, VSG-SPS
- Volunteers
- 6 people
- Sponsor
- Columbia University
Bariatric Surgery, Abdominoplasty
Effect of a Preoperative Oral Collagen-Based Formulation on Dermal Collagen Content, Wound Outcomes, and Scar Quality
This single-center, randomized, placebo-controlled trial evaluated whether approximately 8 weeks of preoperative supplementation with a 10-g daily collagen-based oral formulation affected dermal collagen content and postoperative…
- Conditions
- Bariatric Surgery, Abdominoplasty, Collagen Synthesis, Skin Physiology
- Trial name
- COLLAGEN (NCT06787924)
- Testing
- Collagen hydrolyzed peptides, Starch
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Obesity
Resolution of Comorbidities, Safety and Efficacy of Greater Curvature Plication in Obese Patients.
Various gastric restrictive procedures have evolved over the years but abandoned due to poor long term weight loss, food intolerance or severe gastroesophageal reflux.
- Trial name
- LGCP (NCT01512940)
- Testing
- Laparoscopic Greater Curvature Plication
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Singh, Kuldeep, M.D., P.A.
Autonomic Dysfunction, Orthostatic Intolerance
Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study
Observational two phase, retrospective and prospective registry study to assess the prevalence of and characterize outcomes of autonomic dysfunction (AD) in patients who undergo bariatric surgery (BS) and to better define the…
- Trial name
- NCT06289413
- Testing
- Development of AD/OI after BS
- Where
- 8 sites in United States
- Volunteers
- 400 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Bariatric Surgery
Effects of Physical Training on Health Markers of Post-bariatric Patients
The purpose of this clinical trial is to study the effects of resistance training program on physical-functional fitness, muscle mass and strength, endothelial function, blood pressure, biochemical markers of cardiovascular risk…
- Trial name
- Obesity (NCT04193397)
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Rio de Janeiro State University
Obesity, Metabolic Syndrome
The Predictive Role of Preoperative Pentraxin-3 (PTX3) in Metabolic and Inflammatory Outcomes After Roux-en-Y Gastric Bypass
This study evaluated the prognostic value of preoperative pentraxin-3 (PTX3) levels in predicting weight loss, inflammatory resolution (CRP, IL-6), and metabolic improvements (HOMA-IR) following Roux-en-Y gastric bypass in…
- Conditions
- Obesity, Metabolic Syndrome, Insulin Resistance, Inflammation
- Trial name
- PTX3-BYPASS (NCT07241741)
- Testing
- Biomarker Stratification by PTX3
- Volunteers
- 23 people
- Sponsor
- Istanbul University
Type 2 Diabetes Mellitus, Bariatric Surgery
Prospective Controlled Trial on Surgical Treatment of Type 2 Diabetes Patients With BMI 25-30 by Means of Biliopancreatic Diversion
A previous prospective study of BPD effect on type 2 diabetes patients with BMI 25-35 (DIA-CHIR) showed that T2DM is less sensitive to BPD beneficial effect in the simply overweight patients.
- Conditions
- Type 2 Diabetes Mellitus, Bariatric Surgery, Biliopancreatic Diversion
- Trial name
- DIA-BPD 25-30 (NCT01046994)
- Testing
- biliopancreatic diversion, antidiabetics
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Pain, Postoperative
Pre-emptive Quadratus Lumborum Block for Laparoscopic Bariatric Surgery
The purpose of this study was to determine the effectiveness of pre-emptive Quadratus lumborum block on intra, postoperative pain assessment and opioid requirements in laparoscopic bariatric procedures.
- Trial name
- NCT04294329
- Testing
- US-guided Quadratus lumborum block., Bupivacaine, Saline
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypoglycemia
Mechanisms of Post-Bariatric Hypoglycemia
Post-bariatric hypoglycemia (PBH) is an increasingly recognized syndrome that is incompletely understood. The purpose of this study is to increase our level of understanding by investigating mechanisms contributing to this…
- Trial name
- NCT04428866
- Testing
- Continuous Glucose Monitoring, activity monitor, Mixed meal tolerance test
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Obesity, Morbid
Glycemic Variability After SASI Versus Roux-en-Y Gastric Bypass
The GLUBARI trial is a prospective, randomized, single-center clinical study comparing two bariatric surgical procedures in adults with morbid obesity: Single Anastomosis Sleeve Ileal Bypass (SASI) and Roux-en-Y Gastric Bypass…
- Trial name
- GLUBARI (NCT07872397)
- Testing
- Single Anastomosis Sleeve Ileal Bypass, Roux-en-Y Gastric Bypass
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Obesity
Assessment of Outcomes Following Bariatric Surgery for Mississippi State Employees
Objective: to assess the health and economic outcomes (weight lost, change in control of chronic diseases such as diabetes, quality of life, work productivity, health care cost, etc) associated with bariatric (weight-loss)…
- Trial name
- NCT01162668
- Where
- 4 sites in United States
- Volunteers
- 165 people
- Sponsor
- University of Mississippi Medical Center
Non-Alcoholic Fatty Liver Disease
The Effect of Bariatric Surgery on Hepatic Metabolism in Non-Alcoholic Fatty Liver Disease
The purpose of this study is to investigate the mechanisms underlying bariatric surgery-induced resolution of non-alcoholic fatty liver disease.
- Trial name
- BASIC (NCT05551559)
- Testing
- bariatric surgery
- Where
- Finland
- Volunteers
- 180 people
- Sponsor
- Helsinki University Central Hospital
Obesity, Type 2 Diabetes
Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes
The purpose of this study is to determine the effects of bariatric surgery on blood sugar control and underlying mechanisms that contribute to type 2 diabetes in men and women with a BMI between 27 and 42.
- Trial name
- STAMPEDEII (NCT01278823)
- Testing
- laparoscopic roux en y gastric bypass operation, medical management
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The Cleveland Clinic
Bariatric Surgery
Monitoring Changes in Endotracheal Tube Cuff Pressure During Laparoscopic Bariatric Surgery
This prospective observational cohort study was designed to assess the relationship between ETT cuff pressures and airway pressures in obese patients undergoing laparoscopic bariatric surgery.
- Trial name
- NCT06738875
- Testing
- manometre
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital